Abstract: The present invention is related to a flexible substrate structure for microneedle arrays and its manufacturing method, whose structure mainly comprising: tapered shape objects and flexible substrate. Wherein, structure of the tapered shape object is composed of a tip, sidewalls, and a base. Meanwhile, the flexible substrate winds tightly around sidewalls of tapered shape objects and is set up on, yet covers the base surface of tapered shape object which faces the tip of tapered shape object. Because the structure applies a flexible substrate along with tapered shape objects, hence, the fit-to-body capability is increased and allows thereof more appropriate for backside drug delivery, as well as sufficiently bring the characteristic of large-area manufacturing into full play.

Abstract: A micro-filter for filtering blood cells has a plurality of filtering channel structures, each having a first through hole and a first concave portion connecting to each other, and a plurality of through channel structures respectively connect to the filtering channel structures. Each defines a second through hole opposite the first concave portion, whereby the filtering channel structures are respectively attached to the through channel structures to provide more than two filtering effects.

Abstract: A micro-filter for filtering blood cells has a plurality of filtering channel structures, each having a first through hole and a first concave portion connecting to each other, and a plurality of through channel structures respectively connect to the filtering channel structures. Each defines a second through hole opposite the first concave portion, whereby the filtering channel structures are respectively attached to the through channel structures to provide more than two filtering effects.

Abstract: An apparatus for adjusting the biological clock of a traveler is constructed to has a body, which can be made in the form of an article of clothing for wear by a user or a footstool for resting the user's legs, and a light source installed in the body and used to emit light of a wavelength within about 400 nm-700 nm to irradiate a part of the body of the traveler having many blood vessels relatively close to the surface, a location at which light interacts with photoactive substances in the blood.

Abstract: The present invention is related to a flexible substrate structure for microneedle arrays and its manufacturing method, whose structure mainly comprising: tapered shape objects and flexible substrate. Wherein, structure of the tapered shape object is composed of a tip, sidewalls, and a base. Meanwhile, the flexible substrate winds tightly around sidewalls of tapered shape objects and is set up on, yet covers the base surface of tapered shape object which faces the tip of tapered shape object. Because the structure applies a flexible substrate along with tapered shape objects, hence, the fit-to-body capability is increased and allows thereof more appropriate for backside drug delivery, as well as sufficiently bring the characteristic of large-area manufacturing into full play.

Abstract: A clutching mechanism includes at least one elastic layer with a deformable area in which at least two micro/nano pins are erected. A driving mechanism is utilized to deform the deformable area in a way that those micro/nano pins move closer to each other. The distance between the tips of those micro/nano pins, namely, the clutching points, is thereby reduced, so as to grasp a micro/nano object. Further, to fit in with the shape of a micro/nano object, those micro/nano pins can be made into various shapes. It is a further effect that, when the driving mechanism is a vacuum pump or a pneumatic pump, the clutching force exerted on a micro/nano object can be adjusted by varying the pressure difference produced by the pump.