Patents by Inventor Guang-Rong Sun

Guang-Rong Sun has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Conserved T-cell receptor sequences
    Patent number: 6303750
    Abstract: Four unique transcripts have been isolated from the &bgr; chain of the T cell receptor in T cells in the synovial tissue of a patient with rheumatoid arthritis. Two of these transcripts were isolated from fresh synovial tissue and two were isolated from a T cell line derived from the synovial tissue. The sequences of the four transcripts are highly homologous, with a conserved amino acid sequence of IGQ_N in the highly diverse V-D junction. The &agr; chain and the antigenic specificity of the T cell line derived transcripts has also been characterized.
    Type: Grant
    Filed: April 6, 2000
    Date of Patent: October 16, 2001
    Assignee: New York Society for the Ruptured and Crippled Maintaining the Hopital for Special Surgery
    Inventors: Steven M. Friedman, Mary K. Crow, Yixin Li, Joseph R. Tumang, Guang-Rong Sun
  • DNA encoding conserved T-cell receptor sequences
    Patent number: 6084087
    Abstract: Four unique transcripts have been isolated from the .beta. chain of the T cell receptor in T cells in the synovial tissue of a patient with rheumatoid arthritis. Two of these transcripts were isolated from fresh synovial tissue and two were isolated from a T cell line derived from the synovial tissue. The sequences of the four transcripts are highly homologous, with a conserved amino acid sequence of IGQ.sub.-- N in the highly diverse V-D junction. The .alpha. chain and the antigenic specificity of the T cell line derived transcripts has also been characterized.
    Type: Grant
    Filed: October 28, 1997
    Date of Patent: July 4, 2000
    Assignee: New York Society For the Ruptured and Crippled Maintaing the Hospital for Special Surgery
    Inventors: Steven M. Friedman, Mary K. Crow, Yixin Li, Joseph R. Tumang, Guang-Rong Sun