Patents by Inventor Guangzhong Yang

Guangzhong Yang has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 7112605
    Abstract: The invention relates to sulfonyl-containing 3,4-diaryl-3-pyrrolin-2-ones compounds having formula (I) wherein R1 is selected from the group consisting of 4-methylsulfonyl, 4-aminosulfonyl, hydrogen, 2-, 3-, or 4-halogen, C1–C6-alkyl, cyclopentyl, cyclohexyl, C1–C4-alkoxy, hydroxy, cyano, nitro, amino or trifluoromethyl; R2 is selected from the group consisting of 4-methylsulfonyl, 4-aminosulfonyl, hydrogen, 2-, 3-, or 4-halogen, C1–C6-alkyl, cyclopentyl, cyclohexyl, C1–C4-alkoxy, hydroxy, cyano, nitro, amino or trifluoromethyl; and R3 is selected from the group consisting of hydrogen, methyl, ethyl, n-propyl, i-propyl, c-propyl, n-butyl, isobutyl; provided that when R1 is a methylsulfonyl or aminosulfonyl group, R2 is any group as defined above except a methylsulfonyl or aminosulfonyl group; and when R2 is a methylsulfonyl or aminosulfonyl group, R1 is any group as defined above except a methylsulfonyl or aminosulfonyl group, also to processes for the preparation of such compounds, to pharmaceutical co
    Type: Grant
    Filed: May 14, 2003
    Date of Patent: September 26, 2006
    Assignees: Research Institute of Materia Medica Chinese Acadamy of Medical Sciences, Jiangsu Hengrui Medicine Company Ltd.
    Inventors: Zongru Guo, Guifang Cheng, Fengming Chu, Ai Ping Bai, Wen Hui Hu, Fang Shen, Guangzhong Yang, Boling Xu
  • Patent number: 6689808
    Abstract: The invention relates to compounds of formula (I): wherein R1 represents alkyl or ureido, R2 represents alkyl or hydrogen, or R1 and R2 together form a 5- or 6-membered ring, R3 represents CN, NO2, NRaR′a, NRaSO2R′a, NRaCZR5 or CZNRaR′a, R4 represents hydrogen or R3, and medicinal products containing the same which are useful in treating or preventing epilepsy and neurodegenerative diseases.
    Type: Grant
    Filed: December 26, 2002
    Date of Patent: February 10, 2004
    Assignee: Les Laboratoires Servier
    Inventors: Zongru Guo, Fengming Chu, Juntian Zhang, Guangzhong Yang, Bailing Xu, Xinyi Niu, Zhihong Ren, Pierre Lestage, Pierre Renard
  • Publication number: 20030220393
    Abstract: The invention relates to compounds of formula (I): wherein R1 represents an alkyl or ureido group, R2 represents an alkyl group or a hydrogen atom, or R1 and R2 together form a 5- or 6-membered ring, R3 represents a group CN, NO2, NRaR′a, NRaSO2,R′aCZR5 or CZNRaR′a, R4 represents a hydrogen atom or a group R3.
    Type: Application
    Filed: December 26, 2002
    Publication date: November 27, 2003
    Inventors: Zongru Guo, Fengming Chu, Juntian Zhang, Guangzhong Yang, Bailing Xu, Xinyi Niu, Zhihong Ren, Pierre Lestage, Pierre Renard