Patents by Inventor Guangchun BAI

Guangchun BAI has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Cyclic-di-AMP specific detection
    Patent number: 10048254
    Abstract: The present disclosure provides a simple yet fast, cost effective, reliable method for the detection and quantification of cyclic-di-adenosine monophosphate (c-di-AMP) by measuring c-di-AMP binding to a c-di-AMP-binding protein (CabP). A sample is contacted with CabP in the presence of biotin-labeled c-di-AMP. Once binding has reached equilibrium, unbound c-di-AMP is removed and the CabP-bound c-di-AMP is contacted with an enzyme-conjugated biotin-binding protein and a chromogenic substrate to generate a detectable signal. The signal generated correlates to the amount of unlabeled c-di-AMP in the sample.
    Type: Grant
    Filed: June 3, 2014
    Date of Patent: August 14, 2018
    Assignee: ALBANY MEDICAL COLLEGE
    Inventor: Guangchun Bai
  • CYCLIC-DI-AMP SPECIFIC DETECTION
    Publication number: 20160123966
    Abstract: The present disclosure provides a simple yet fast, cost effective, reliable method for the detection and quantification of cyclic-di-adenosine monophosphate (c-di-AMP) by measuring c-di-AMP binding to a c-di-AMP-binding protein (CabP). A sample is contacted with CabP in the presence of biotin-labeled c-di-AMP. Once binding has reached equilibrium, unbound c-di-AMP is removed and the CabP-bound c-di-AMP is contacted with an enzyme-conjugated biotin-binding protein and a chromogenic substrate to generate a detectable signal. The signal generated correlates to the amount of unlabeled c-di-AMP in the sample.
    Type: Application
    Filed: June 3, 2014
    Publication date: May 5, 2016
    Applicant: ALBANY MEDICAL COLLEGE
    Inventor: Guangchun BAI