Abstract: The invention relates to a double-microenvironment three-layer bionic hydrogel scaffold and a preparation method and application thereof, which are characterized in that includes a cartilage layer GL-HPKGN, an intermediate layer GL-GMA, and a bone layer GL-HP/GMAAT; by an enzymatic crosslinking reaction based on hydroxyphenylpropionic acid (HPA), kartogenin (KGN) is grafted onto gelatin to form a cartilage-specific microenvironment in GL-HPKGN; Based on hydroxyphenylpropionic acid (HPA), a dual crosslinking network was formed by enzyme crosslinking reaction and methacryloyl-glycidyl dimethicone (GMA) photo-crosslinking reaction, which was used to graft atorvastatin (AT) onto gelatin, forming GL-HP/GMAAT with bone-specific microenvironment; the intermediate layer GL-GMA was beneficial for forming a clear and defined cartilage-bone integrated structure. The introduction of the tide-line intermediate layer GL-GMA facilitated the formation of well-defined chondro-bone integrated structures.

Abstract: A vapor chamber structure includes: a first plate body and a second plate body, which are mechanically processed and thinned, the first plate body having a first side, a second side and an opening, the second plate body having a third side and a fourth side, the first and second plate bodies being correspondingly mated with each other to define an airtight chamber, a working liquid being filled in the airtight chamber; a heat conduction block disposed at the opening, the heat conduction block having a first face and a second face; a first capillary structure layer disposed on the first side of the first plate body; and a second capillary structure layer formed on the second face of the heat conduction block. In case the first and second plate bodies are thinned to cause insufficient structural strength and planarity, the heat conduction block can reinforce the vapor chamber structure.