Patents by Inventor Guangfei Li
Guangfei Li has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Patent number: 11389101Abstract: The present application discloses a method for identifying arrhythmia, a device for identifying arrhythmia, and a computer readable medium. The method includes: acquiring a type of arrhythmia to be identified; acquiring an ECG signal collected by an ECG acquisition device; detecting feature wave information in the ECG signal according to the type of arrhythmia to be identified; extracting a feature parameter from the denoised ECG signal and the feature wave information according to the type of arrhythmia to be identified; and identifying, by a classifier, an occurrence of the type of arrhythmia to be identified according to the feature parameter.Type: GrantFiled: June 21, 2019Date of Patent: July 19, 2022Assignee: BOE TECHNOLOGY GROUP CO., LTD.Inventors: Guangfei Li, Yang Han
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Patent number: 11375906Abstract: A method for detecting fetal blood oxygen saturation, including: using at least two detection light of different wavelengths, to irradiate a fetus in an examined pregnant woman's abdomen in a time-sharing manner and acquiring first photoplethysmography signals corresponding to the abdomen under irradiation of the respective wavelengths of detection light, and to irradiate a detection site except the examined pregnant woman's abdomen in a time-sharing manner and acquiring second photoplethysmography signals corresponding to the detection site under irradiation of the respective wavelengths of the detection light; determining a target photoplethysmography signal of the fetus that corresponds to the detection light of each wavelength, according to the first photoplethysmography signals and the second photoplethysmography signals that correspond to the detection light of each wavelength; and determining the fetal blood oxygen saturation, according to respective target photoplethysmography signals determined.Type: GrantFiled: December 25, 2019Date of Patent: July 5, 2022Assignee: BOE Technology Group Co., Ltd.Inventors: Xun Zhang, Yang Han, Guangfei Li, Hui Du, Siyang Liang
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Patent number: 11259721Abstract: Disclosed are a method and device for detecting the concentration of total hemoglobin in blood. A differential path factor corresponding to a subject is determined according to a physiological parameter of the subject and a predetermined table of a corresponding relation between the physiological parameter and the differential path factor.Type: GrantFiled: June 12, 2019Date of Patent: March 1, 2022Assignee: BOE Technology Group Co., Ltd.Inventors: Xun Zhang, Guangfei Li
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Patent number: 11109794Abstract: A method for processing ECG signals includes: removing peak position information of any R wave of a plurality of R waves in a plurality of ECG signals if it is determined that a first RR interval is less than or equal to a first RR interval threshold, and an amplitude of the R wave is less than or equal to a first R wave amplitude threshold; and detecting at least one new R wave in a first RR interval if it is determined that the first RR interval is greater than or equal to a second RR interval threshold; obtaining peak position information of the at least one new R wave, and then storing peak position information of any new R wave if it is determined that an amplitude of the new R wave is greater than or equal to a second R wave amplitude threshold.Type: GrantFiled: May 16, 2019Date of Patent: September 7, 2021Assignee: BOE TECHNOLOGY GROUP CO., LTD.Inventors: Guangfei Li, Qi Yang, Xun Zhang
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Publication number: 20210204820Abstract: A method for detecting fetal blood oxygen saturation, including: using at least two detection light of different wavelengths, to irradiate a fetus in an examined pregnant woman's abdomen in a time-sharing manner and acquiring first photoplethysmography signals corresponding to the abdomen under irradiation of the respective wavelengths of detection light, and to irradiate a detection site except the examined pregnant woman's abdomen in a time-sharing manner and acquiring second photoplethysmography signals corresponding to the detection site under irradiation of the respective wavelengths of the detection light; determining a target photoplethysmography signal of the fetus that corresponds to the detection light of each wavelength, according to the first photoplethysmography signals and the second photoplethysmography signals that correspond to the detection light of each wavelength; and determining the fetal blood oxygen saturation, according to respective target photoplethysmography signals determined.Type: ApplicationFiled: December 25, 2019Publication date: July 8, 2021Applicant: BOE Technology Group Co., Ltd.Inventors: Xun Zhang, Yang Han, Guangfei Li, Hui Du, Siyang Liang
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Publication number: 20200093409Abstract: Disclosed are a method and device for detecting the concentration of total hemoglobin in blood. A differential path factor corresponding to a subject is determined according to a physiological parameter of the subject and a predetermined table of a corresponding relation between the physiological parameter and the differential path factor.Type: ApplicationFiled: June 12, 2019Publication date: March 26, 2020Inventors: Xun ZHANG, Guangfei LI
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Publication number: 20200015695Abstract: The present application discloses a method for identifying arrhythmia, a device for identifying arrhythmia, and a computer readable medium. The method includes: acquiring a type of arrhythmia to be identified; acquiring an ECG signal collected by an ECG acquisition device; detecting feature wave information in the ECG signal according to the type of arrhythmia to be identified; extracting a feature parameter from the denoised ECG signal and the feature wave information according to the type of arrhythmia to be identified; and identifying, by a classifier, an occurrence of the type of arrhythmia to be identified according to the feature parameter.Type: ApplicationFiled: June 21, 2019Publication date: January 16, 2020Inventors: Guangfei LI, Yang HAN
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Publication number: 20200015688Abstract: A blood pressure measurement method, a blood pressure measurement device, and a storage medium are provided. The method includes: acquiring a video of a part of a human body, and generating a PPGi signal based on the video; extracting feature information from the PPGi signal; fitting blood pressure models based on the feature information, and acquiring blood pressure data corresponding to each heartbeat, wherein the blood pressure models include a systolic blood pressure linear model and a diastolic blood pressure exponential model.Type: ApplicationFiled: July 10, 2019Publication date: January 16, 2020Applicant: BOE TECHNOLOGY GROUP CO., LTD.Inventors: Guangfei LI, Xun ZHANG, Hui DU
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Publication number: 20190365268Abstract: Provided is a method and an apparatus for processing ECG signals and an ECG machine, for improving a correct detection rate of R waves in the ECG signals recorded by a recorder.Type: ApplicationFiled: May 16, 2019Publication date: December 5, 2019Inventors: Guangfei LI, Qi YANG, Xun ZHANG
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Patent number: 10428107Abstract: A method for separating and purifying recombinant human serum albumin (rHSA) from transgenic rice grain, sequentially comprising the steps of: 1) subjecting crude extract of rHSA to cation exchange chromatography to obtain primary product I; 2) subjecting the primary product I to anion exchange chromatography to obtain secondary product II; 3) subjecting the secondary product II to hydrophobic chromatography to obtain purified rHSA. The method may further comprise a step of ceramic hydroxyapatite chromatography prior to the hydrophobic chromatography. The method has the advantages of low cost and easy operation. The resultant rHSA has a purity of about 99% by HPLC.Type: GrantFiled: March 9, 2018Date of Patent: October 1, 2019Assignee: Healthgen Biotechnology Co., Ltd.Inventors: Daichang Yang, Yang He, Guangfei Li, Jingru Liu
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Patent number: 10183984Abstract: A method for extracting recombinant human serum albumin (rHSA) from transgenic rice grain is provided, comprising the steps of: 1) grinding dehusked rice containing rHSA into milled rice grain with a fineness of 80˜120 mesh, which is mixed with a extraction buffer in a w/v ratio of 1:5, then extracting at 55˜60° C. for 1˜3 hours to obtain mixture I; said extraction buffer comprises 10˜30 mM phosphate buffer, 10˜20 mM sodium acetate, 15˜30 mM ammonium sulfate and 5˜20 mM sodium caprylate and has a pH of 6.5˜8; 2) adjusting the pH of mixture I to 4.0˜4.5, followed by precipitating at room temperature for 3˜12 hours to obtain mixture II; 3) filtering the mixture II and collecting the filtrate, to obtain a solution containing high concentration of rHSA. The concentration of rHSA in the resultant solution is 650˜660 ?g/mL, which increases by 1.15 times comparing to the extraction amount before improvement, and the amount of non-target protein is reduced by 2.46 times.Type: GrantFiled: January 14, 2016Date of Patent: January 22, 2019Assignee: Healthgen Biotechnology Corp.Inventors: Daichang Yang, Yang He, Guangfei Li
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Publication number: 20180194801Abstract: A method for separating and purifying recombinant human serum albumin (rHSA) from transgenic rice grain, sequentially comprising the steps of: 1) subjecting crude extract of rHSA to cation exchange chromatography to obtain primary product I; 2) subjecting the primary product I to anion exchange chromatography to obtain secondary product II; 3) subjecting the secondary product II to hydrophobic chromatography to obtain purified rHSA. The method may further comprise a step of ceramic hydroxyapatite chromatography prior to the hydrophobic chromatography. The method has the advantages of low cost and easy operation. The resultant rHSA has a purity of about 99% by HPLC.Type: ApplicationFiled: March 9, 2018Publication date: July 12, 2018Applicant: HEALTHGEN BIOTECHNOLOGY CO., LTD.Inventors: Daichang YANG, Yang HE, Guangfei LI, Jingru LIU
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Patent number: 9951100Abstract: A method for separating and purifying recombinant human serum albumin (rHSA) from transgenic rice grain, sequentially comprising the steps of: 1) subjecting crude extract of rHSA to cation exchange chromatography to obtain primary product I; 2) subjecting the primary product I to anion exchange chromatography to obtain secondary product II; 3) subjecting the secondary product II to hydrophobic chromatography to obtain purified rHSA. The method may further comprise a step of ceramic hydroxyapatite chromatography prior to the hydrophobic chromatography. The method has the advantages of low cost and easy operation. The resultant rHSA has a purity of about 99% by HPLC.Type: GrantFiled: April 1, 2015Date of Patent: April 24, 2018Assignee: HEALTHGEN BIOTECHNOLOGY CO., LTD.Inventors: Daichang Yang, Yang He, Guangfei Li, Jingru Liu
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Publication number: 20160122414Abstract: A method for extracting recombinant human serum albumin (rHSA) from transgenic rice grain is provided, comprising the steps of: 1) grinding dehusked rice containing rHSA into milled rice grain with a fineness of 80˜120 mesh, which is mixed with a extraction buffer in a wily ratio of 1:5, then extracting at 5560° C. for 1˜3 hours to obtain mixture 1; said extraction buffer comprises 10˜30 mM phosphate buffer, 10˜20 mM sodium acetate, 1530 mM ammonium sulfate and 5˜20 mM sodium caprylate and has a pH of 6.5˜8; 2) adjusting the pH of mixture I to 4.0˜4.5, followed by precipitating at room temperature for 3˜12 hours to obtain mixture 3) filtering the mixture 11 and collecting the filtrate, to obtain a solution containing high concentration of rHSA. The concentration of rHSA in the resultant solution is 650˜660 ?g/mL, which increases by 1.15 times comparing to the extraction amount before improvement, and the amount of non-target protein is reduced by 2.46 times.Type: ApplicationFiled: January 14, 2016Publication date: May 5, 2016Applicant: Healthgen Biotechnology Corp.Inventors: Daichang YANG, Yang He, Guangfei Li
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Patent number: 9255138Abstract: A method for extracting recombinant human serum albumin (rHSA) from transgenic rice grain is provided, comprising the steps of: 1) grinding dehusked rice containing rHSA into milled rice grain with a fineness of 80˜120 mesh, which is mixed with a extraction buffer in a w/v ratio of 1:5, then extracting at 55˜60° C. for 1˜3 hours to obtain mixture I; said extraction buffer comprises 10˜30 mM phosphate buffer, 10˜20 mM sodium acetate, 15˜30 mM ammonium sulfate and 5˜20 mM sodium caprylate and has a pH of 6.5˜8; 2) adjusting the pH of mixture I to 4.0˜4.5, followed by precipitating at room temperature for 3˜12 hours to obtain mixture II; 3) filtering the mixture II and collecting the filtrate, to obtain a solution containing high concentration of rHSA. The concentration of rHSA in the resultant solution is 650˜660 ?g/mL, which increases by 1.15 times comparing to the extraction amount before improvement, and the amount of non-target protein is reduced by 2.46 times.Type: GrantFiled: August 10, 2011Date of Patent: February 9, 2016Assignee: Healthgen Biotechnology Co., Ltd.Inventors: Daichang Yang, Yang He, Guangfei Li
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Publication number: 20150203530Abstract: A method for separating and purifying recombinant human serum albumin (rHSA) from transgenic rice grain, sequentially comprising the steps of: 1) subjecting crude extract of rHSA to cation exchange chromatography to obtain primary product I; 2) subjecting the primary product Ito anion exchange chromatography to obtain secondary product II; 3) subjecting the secondary product II to hydrophobic chromatography to obtain purified rHSA. The method may further comprise a step of ceramic hydroxyapatite chromatography prior to the hydrophobic chromatography. The method has the advantages of low cost and easy operation. The resultant rHSA has a purity of about 99% by HPLC.Type: ApplicationFiled: April 1, 2015Publication date: July 23, 2015Inventors: Daichang YANG, Yang He, Guangfei Li, Jingru Liu
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Patent number: 9023990Abstract: A method for separating and purifying recombinant human serum albumin (rHSA) from transgenic rice grain, sequentially comprising the steps of: 1) subjecting crude extract of rHSA to cation exchange chromatography to obtain primary product I; 2) subjecting the primary product I to anion exchange chromatography to obtain secondary product II; 3) subjecting the secondary product II to hydrophobic chromatography to obtain purified rHSA. The method may further comprise a step of ceramic hydroxyapatite chromatography prior to the hydrophobic chromatography. The method has the advantages of low cost and easy operation. The resultant rHSA has a purity of about 99% by HPLC.Type: GrantFiled: August 10, 2011Date of Patent: May 5, 2015Assignee: Healthgen Biotechnology Co., Ltd.Inventors: Daichang Yang, Yang He, Guangfei Li, Jingru Liu
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Publication number: 20120202973Abstract: A method for extracting recombinant human serum albumin (rHSA) from transgenic rice grain is provided, comprising the steps of: 1) grinding dehusked rice containing rHSA into milled rice grain with a fineness of 80˜120 mesh, which is mixed with a extraction buffer in a w/v ratio of 1:5, then extracting at 55˜60° C. for 1˜3 hours to obtain mixture I; said extraction buffer comprises 10˜30 mM phosphate buffer, 10˜20 mM sodium acetate, 15˜30 mM ammonium sulfate and 5˜20 mM sodium caprylate and has a pH of 6.5˜8; 2) adjusting the pH of mixture I to 4.0˜4.5, followed by precipitating at room temperature for 3˜12 hours to obtain mixture II; 3) filtering the mixture II and collecting the filtrate, to obtain a solution containing high concentration of rHSA. The concentration of rHSA in the resultant solution is 650˜660 ?g/mL, which increases by 1.15 times comparing to the extraction amount before improvement, and the amount of non-target protein is reduced by 2.46 times.Type: ApplicationFiled: August 10, 2011Publication date: August 9, 2012Applicant: Healthgen Biotechnology Co., Ltd.Inventors: Daichang Yang, Yang He, Guangfei Li
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Publication number: 20120165509Abstract: A method for separating and purifying recombinant human serum albumin (rHSA) from transgenic rice grain, sequentially comprising the steps of: 1) subjecting crude extract of rHSA to cation exchange chromatography to obtain primary product I; 2) subjecting the primary product I to anion exchange chromatography to obtain secondary product II; 3) subjecting the secondary product II to hydrophobic chromatography to obtain purified rHSA. The method may further comprise a step of ceramic hydroxyapatite chromatography prior to the hydrophobic chromatography. The method has the advantages of low cost and easy operation. The resultant rHSA has a purity of about 99% by HPLC.Type: ApplicationFiled: August 10, 2011Publication date: June 28, 2012Applicant: Healthgen Biotechnology Co., Ltd.Inventors: Daichang Yang, Yang He, Guangfei Li, Jingru Liu