Abstract: A method for improving resistance of a fusion reactor inner wall to plasma irradiation by using lamination structure comprises: making a material for facing plasma into multiple metal sheets, laminating the multiple metal sheets together according to a direction perpendicular to a wall surface, and combining the laminated multiple metal sheets with a copper substrate. The method relates to the field of nuclear applications, and is applicable to a plasma-facing surface on an inner wall of an apparatus for conducting a fusion reaction by using hydrogen isotopes. Not only does the method reduce aggregation of hydrogen, helium, and isotopes thereof, and the like, under a surface layer of a tungsten-based material, greatly reducing a blistering phenomenon on a surface thereof, but also reduces thermal fatigue cracking damages.