Patents by Inventor Guanghuang Zhan

Guanghuang Zhan has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20230203545
    Abstract: A method for controlled production of glyceric acid includes, during the glyceric acid fermentation process, real-time online monitoring of at least one of the respiratory quotient and redox potential in the fermentation liquid as well as the fermentation process specific growth rate, and controlling their values within the following ranges: 0.1˜1.5 for respiratory quotient, ?300˜50 mV for redox potential, 0.05˜0.8 for specific growth rate. Process parameters for this method are controlled within predetermined ranges by online monitoring at least one of respiratory quotient (RQ) and redox potential as well as the specific growth rate in the fermentation process, thereby meeting the growth requirements of bacteria, effectively promoting the glycerol metabolism and synthesis and improving the conversion rate.
    Type: Application
    Filed: October 27, 2022
    Publication date: June 29, 2023
    Inventors: Zhichun Zhu, Guanghuang Zhan, Changhua Dai, Luming Xu, Huijuan Zheng, Biqin Chen, Dan Li
  • Publication number: 20230203544
    Abstract: Controlled coenzyme Q10 (CoQ10) fermentation production processes and methods for controlling the CoQ10 fermentation production processes are provided in the present disclosure. The processes may include growing a microbial culture of bacteria by providing a carbon source and an oxygen source for a predetermined period of time, thereby producing CoQ10-containing bacteria, carbon dioxide, and lactate in the bacterial culture. During various stages of the production process, the concentration of carbon dioxide may be maintained at predetermined levels, respectively. Alternatively or additionally, during various stages of the production process, the concentration of lactate may be maintained at predetermined levels, respectively.
    Type: Application
    Filed: February 20, 2023
    Publication date: June 29, 2023
    Applicants: INNER MONGOLIA KINGDOMWAY PHARMACEUTICAL CO., LTD., XIAMEN KINGDOMWAY GROUP COMPANY
    Inventors: Guanghuang ZHAN, Yi WU, Biqin CHEN, Zhichun ZHU, Dan LI
  • Publication number: 20230203543
    Abstract: Controlled coenzyme Q10 (CoQ10) fermentation production processes and methods for controlling the CoQ10 fermentation production processes are provided in the present disclosure. The processes may include growing a microbial culture of bacteria by providing a carbon source and an oxygen source for a predetermined period of time, thereby producing CoQ10-containing bacteria, carbon dioxide, and lactate in the bacterial culture. During various stages of the production process, the concentration of carbon dioxide may be maintained at predetermined levels, respectively. Alternatively or additionally, during various stages of the production process, the concentration of lactate may be maintained at predetermined levels, respectively.
    Type: Application
    Filed: February 20, 2023
    Publication date: June 29, 2023
    Applicants: INNER MONGOLIA KINGDOMWAY PHARMACEUTICAL CO., LTD., XIAMEN KINGDOMWAY GROUP COMPANY
    Inventors: Guanghuang ZHAN, Yi WU, Biqin CHEN, Zhichun ZHU, Dan LI
  • Patent number: 11584942
    Abstract: Controlled coenzyme Q10 (CoQ10) fermentation production processes and methods for controlling the CoQ10 fermentation production processes are provided in the present disclosure. The processes may include growing a microbial culture of bacteria by providing a carbon source and an oxygen source for a predetermined period of time, thereby producing CoQ10-containing bacteria, carbon dioxide, and lactate in the bacterial culture. During various stages of the production process, the concentration of carbon dioxide may be maintained at predetermined levels, respectively. Alternatively or additionally, during various stages of the production process, the concentration of lactate may be maintained at predetermined levels, respectively.
    Type: Grant
    Filed: October 11, 2019
    Date of Patent: February 21, 2023
    Assignees: INNER MONGOLIA KINGDOMWAY PHARMACEUTICAL CO., LTD., XIAMEN KINGDOMWAY GROUP COMPANY
    Inventors: Guanghuang Zhan, Yi Wu, Biqin Chen, Zhichun Zhu, Dan Li
  • Publication number: 20200354757
    Abstract: Controlled coenzyme Q10 (CoQ10) fermentation production processes and methods for controlling the CoQ10 fermentation production processes are provided in the present disclosure. The processes may include growing a microbial culture of bacteria by providing a carbon source and an oxygen source for a predetermined period of time, thereby producing CoQ10-containing bacteria, carbon dioxide, and lactate in the bacterial culture. During various stages of the production process, the concentration of carbon dioxide may be maintained at predetermined levels, respectively. Alternatively or additionally, during various stages of the production process, the concentration of lactate may be maintained at predetermined levels, respectively.
    Type: Application
    Filed: October 11, 2019
    Publication date: November 12, 2020
    Applicants: INNER MONGOLIA KINGDOMWAY PHARMACEUTICAL CO., LTD., XIAMEN KINGDOMWAY GROUP COMPANY
    Inventors: Guanghuang ZHAN, Yi WU, Biqin CHEN, Zhichun ZHU, Dan LI
  • Patent number: 9689008
    Abstract: A fermentation method for producing coenzyme Q10 is provided, including stepwisly culturing of microbial strains capable of producing coenzyme Q10, wherein key promoting factors are added in each stage of culture, and in the stage of culture in a fermentor, dissolved oxygen feedback-fed batch culture technique is adopted to realize the feedback regulation of the production of coenzyme Q10, so as to improve the yield of coenzyme Q10.
    Type: Grant
    Filed: August 10, 2011
    Date of Patent: June 27, 2017
    Assignees: Inner Mongolia Kingdomway Pharmaceutical Limited, Xiamen Kingdomway Group Company
    Inventors: Yi Wu, Biqin Chen, Guanghuang Zhan, Youpao Zhu