Patents by Inventor Guanghui Li

Guanghui Li has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20250099586
    Abstract: Provided is a set of viral vectors, comprising: a first viral vector that carries a first nucleic acid molecule encoding an envelope protein, and a second viral vector that carries a second nucleic acid molecule encoding a fusion protein, the fusion protein comprising: a single-chain antibody capable of binding to CD28 or CD3, and a C-terminal domain, comprising a transmembrane region and an intracellular region, of the envelope protein. The C terminal of the single-chain antibody is connected to the N terminal of the C-terminal domain of the envelope protein, and the envelope protein and the fusion protein are in a non-fusion form. Also provided are a method for obtaining a lentivirus and an obtained lentivirus, a method for introducing a lentivirus into an unactivated T lymphocyte, a method for expressing a target gene, a method for obtaining a CAR-T cell and an obtained CAR-T cell, a pharmaceutical composition, and a use thereof.
    Type: Application
    Filed: January 16, 2023
    Publication date: March 27, 2025
    Applicant: SUNSHINE LAKE PHARMA CO., LTD.
    Inventors: Xiaodan YANG, Shiyou CHEN, Xiuqin ZHU, Linsheng LI, Junji DONG, Guanghui ZHAO, Lijia LI, Xiaofeng CHEN, Wenjia LI
  • Patent number: 12262165
    Abstract: Disclosed are a method and an apparatus for detecting a wearing state of an earphone, an earphone, and a storage medium. The method includes: obtaining a request for detecting the wearing state of the earphone; performing audio collection by a feedback microphone of the earphone to obtain a feedback audio signal; determining a frequency of the audio, and determining a target frequency with a power meeting a preset condition in the feedback audio signal based on the frequency and an audio collection parameter of the feedback microphone; performing a power spectrum analysis on the feedback audio signal to obtain a power spectrum of the feedback audio signal; determining target power information of the target frequency from the power spectrum; and in response to the target power information being not less than a maximum power threshold value set for the target frequency, determining that the wearing state is in-ear state.
    Type: Grant
    Filed: October 1, 2024
    Date of Patent: March 25, 2025
    Assignee: SHENZHEN TONLY SCIENCE AND TECHNOLOGY DEVELOPMENT CO., LTD
    Inventors: Liechao Huang, Yucheng Zhao, Guanghui Han, Jinhui Li, Hua Yan, Xinwen Chen
  • Publication number: 20250088310
    Abstract: Methods, apparatus, and systems that relate to rate matching scheme design for polar coding, PAC coding, or other pre-transformed polar coding are disclosed. In one example aspect, a method for digital communication includes determining, by a first node, an output bit sequence having E bits based on an input bit sequence c having K bits, wherein the output bit sequence is determined based on an output of a polar transform and an output of a repetition operation, and wherein the input of the repetition operation is a portion of a bit sequence before the polar transform. The method also includes transmitting, by the first node, a signal including the output bit sequence to a second node.
    Type: Application
    Filed: November 4, 2024
    Publication date: March 13, 2025
    Inventors: Chulong LIANG, Wei ZHAO, Jin XU, Liguang LI, Guanghui YU, Jian KANG, Qiang FU
  • Publication number: 20250087162
    Abstract: The present application provides a display panel and a display device, the display panel includes: N scan lines, the N is an integer greater than or equal to 1; and J sets of forward and reverse scan pull-down circuits, each set of the forward and reverse scan pull-down circuits includes N forward and reverse scan pull-down modules, at least a part of each of the forward and reverse scan pull-down modules is disposed in the display subarea, and the J is an integer greater than or equal to 1. In each set of the forward and reverse scan pull-down circuits, output terminals of the N forward and reverse scan pull-down modules are connected to the N scan lines in a one-to-one correspondence.
    Type: Application
    Filed: March 29, 2023
    Publication date: March 13, 2025
    Applicant: WUHAN CHINA STAR OPTOELECTRONICS TECHNOLOGY CO., LTD.
    Inventors: Mingyue LI, Chao TIAN, Yanqing GUAN, Fei AI, Guanghui LIU
  • Publication number: 20250089363
    Abstract: The present disclosure provides semiconductor devices. A first active layer is disposed on a substrate. A first insulation layer covers the first active layer and is provided with a first via hole. A second active layer is disposed on the first insulation layer. A third active layer is disposed in the first via hole and connects the first active layer and the second active layer, so that a channel length of the semiconductor device is determined by a thickness of the first insulation layer, and a channel width of the semiconductor device is determined by a circumference of the first via hole.
    Type: Application
    Filed: June 29, 2023
    Publication date: March 13, 2025
    Applicant: Wuhan China Star Optoelectronics Technology Co., Ltd.
    Inventors: Zhifu LI, Guanghui LIU, Fei AI, Chengzhi LUO
  • Publication number: 20250081522
    Abstract: The present application provides a thin film transistor and an electronic device thereof. An active layer of the thin film transistor includes: a first active layer, a channel layer and a second active layer that are stacked, the first active layer includes a first doped portion and a second doped portion, the first doped portion is connected to the channel layer and the second doped portion, and a concentration of dopant ions in the first doped portion is less than a concentration of dopant ions in the second doped portion. The leakage current is reduced, and the mobility in the “channel region” of the thin film transistor is improved.
    Type: Application
    Filed: June 29, 2023
    Publication date: March 6, 2025
    Applicant: WUHAN CHINA STAR OPTOELECTRONICS TECHNOLOGY CO., LTD.
    Inventors: Zhifu LI, Guanghui LIU, Fei AI, Dewei SONG, Chengzhi LUO
  • Publication number: 20250078728
    Abstract: An embodiment of the present disclosure is directed to a display panel. The display panel includes a plurality of scan lines and a plurality of forward and reverse scan pull-down circuit. The plurality of scan lines is located on the display area. Each of the forward and reverse scan pull-down circuits includes a forward scan control module, a reverse scan control module, and a pull-down module located on a display area. The pull-down module includes an output terminal and a control terminal coupled to an output terminal of the forward scan control module and an output terminal of the reverse scan control module.
    Type: Application
    Filed: February 8, 2023
    Publication date: March 6, 2025
    Applicant: WUHAN CHINA STAR OPTOELECTRONICS TECHNOLOGY CO., LTD.
    Inventors: Chao TIAN, Mingyue LI, Yanqing GUAN, Haiming CAO, Fei AI, Guanghui LIU
  • Publication number: 20250070912
    Abstract: Methods, apparatus, and systems that relate to rate matching scheme design for polar coding, PAC coding, or other pre-transformed polar coding are described. One example method includes determining, by a first node, an output bit sequence having E bits based on an input bit sequence having K bits, wherein the output bit sequence is determined by 1) performing a polar transform with H components and 2) performing either no pre-transform or at least two pre-transform operations; wherein the polar transform is based on H polar matrices G(N0), G(N1), . . . , G(NH?1), wherein H, K and E are integers greater than 1, wherein a polar matrix G(Ni) is of size Ni. The method also includes transmitting, by the first node, a signal including the output bit sequence to a second node.
    Type: Application
    Filed: November 1, 2024
    Publication date: February 27, 2025
    Inventors: Chulong LIANG, Wei ZHAO, Jin XU, Liguang LI, Guanghui YU, Jian KANG, Qiang FU
  • Publication number: 20250072093
    Abstract: A display panel is provided. The display panel includes a substrate and includes a first ohmic contact structure, a first boss, a second ohmic contact structure, a semiconductor structure, and a gate which are stacked on the substrate. The first boss includes at least one sidewall. By arranging the semiconductor structure on the sidewall of the first boss, a length of a channel can be shortened by using an existing technology, and a dimension of a thin film transistor can be reduced, so that an integration level of the thin film transistor in the display panel can be improved.
    Type: Application
    Filed: November 7, 2022
    Publication date: February 27, 2025
    Inventors: Zhifu LI, Guanghui LIU, Fei AI, Dewei SONG, Zhuang LI
  • Publication number: 20250062779
    Abstract: Methods, apparatus, and systems that relate to rate matching scheme design for polar coding, PAC coding, or other pre-transformed polar coding are disclosed. In one example aspect, a method for digital communication includes determining, by a first node, an output bit sequence having E bits based on an input bit sequence having K bits, wherein the output bit sequence is determined by performing a polar transform with H components and a pre-transform; wherein the polar transform is based on H polar matrices G(N0), G(N1), . . . , G(NH?0), wherein E, K, H are integers greater than 1, wherein a polar matrix G(N0) is of size Ni. The method also includes transmitting, by the first node, a signal including the output bit sequence to a second node.
    Type: Application
    Filed: October 31, 2024
    Publication date: February 20, 2025
    Inventors: Chulong LIANG, Wei ZHAO, Jin XU, Liguang LI, Guanghui YU, Jian KANG, Qiang FU
  • Patent number: 12225943
    Abstract: An atomizer, comprising: a housing, an e-liquid storage cavity being provided in the housing; an atomization assembly, provided in the housing and provided with an air exchange channel, the air exchange channel being communicated with the outside and the e-liquid storage cavity, and the e-liquid storage cavity being used for storing e-liquid supplied to the atomization assembly; and an e-liquid separation piece, having air permeability and used for blocking the air exchange channel to absorb the e-liquid from the e-liquid storage cavity. External air can enter the e-liquid storage cavity by means of the air exchange channel and the e-liquid separation piece.
    Type: Grant
    Filed: June 26, 2019
    Date of Patent: February 18, 2025
    Assignee: SHENZHEN SMOORE TECHNOLOGY LIMITED
    Inventors: Xiaoping Li, Guanghui Li
  • Publication number: 20250055595
    Abstract: Methods, apparatus, and systems that relate to Polarization-Adjusted Convolutional (PAC) coding with variable lengths are disclosed. In one example aspect, a method for digital communication includes determining, by a first node, an output bit sequence having E bits based on an input bit sequence having K bits. The output bit sequence is determined based on a transform that is applied prior to applying a Polar transform having a size of N. The transform is based on at least one index set that is a subset of a set of bit indices. The set of bit indices comprises all non-negative integers that are less than N and wherein K<N and K<E. The method also includes transmitting, by the first node, a signal including the output bit sequence to a second node.
    Type: Application
    Filed: October 24, 2024
    Publication date: February 13, 2025
    Inventors: Chulong LIANG, Jin XU, Wei ZHAO, Liguang LI, Guanghui YU, Jian KANG, Qiang FU
  • Patent number: 12171538
    Abstract: A three-dimensional (3D) magnetic particle imaging (MPI) method and system without rotating a field-free line (FFL) are disclosed. In accordance with the method, an FFL is generated such that magnetic particles in a region far from the FFL enter a magnetic saturation state. Further, a non-uniform mixed-frequency excitation magnetic field parallel to the FFL is applied to generate intermodulation response signals. In addition, the intermodulation response signals are acquired, amplified and filtered. Moreover, the intermodulation response signals are transmitted to a digital signal processing unit and an image reconstruction unit, and an encoding matrix is constructed. Additionally, a one-dimensional (1D) concentration distribution of the magnetic particles is reconstructed based on the encoding matrix and an actually measured voltage signal. The FFL is driven for line-by-line scanning along a vertical plane of the FFL, thereby achieving 3D imaging.
    Type: Grant
    Filed: July 3, 2024
    Date of Patent: December 24, 2024
    Assignee: Beihang University
    Inventors: Jie Tian, Yanjun Liu, Yu An, Guanghui Li
  • Publication number: 20240368264
    Abstract: An anti-TSLP nanobody and a use thereof are provided. A coding sequence encoding the anti-TSLP nanobody, corresponding expression vector and host cell capable of expressing the nanobody, and a method for producing the anti-TSLP nanobody are also provided. The anti-TSLP nanobody has a good TSLP/TSLPR blocking activity and is expressed using pichia pastoris. Its fermenter expression yield can reach 17-23 g/L.
    Type: Application
    Filed: May 16, 2022
    Publication date: November 7, 2024
    Inventors: Yakun WAN, Guanghui LI, Min ZHU, Junwei GAI, Xiaoning SHEN
  • Publication number: 20240349813
    Abstract: An atomizer includes: a liquid storage room for storing liquid aerosol generation substrate; an atomization main body having an atomization assembly, the atomization assembly including a liquid absorbing surface in liquid guide communication with the liquid storage room; and at least one vent channel having a vent tube provided on an inner wall surface of the liquid storage room, the vent tube including a vent opening that is away from the inner wall surface and/or the liquid absorbing surface.
    Type: Application
    Filed: June 28, 2024
    Publication date: October 24, 2024
    Inventors: Guanghui LI, Boxue GONG
  • Patent number: 12117473
    Abstract: A method and system for measuring broadband impedance of a renewable energy power generation device. A voltage disturbance is injected into the renewable energy power generation device by using a disturbance injection device, and three-phase voltage and three-phase current of each of preset measurement points are acquired. Relevant variables before the renewable energy power generation device is decoupled from a measurement device and impedance of a power grid, are calculated according to the three-phase voltage and the three-phase current of each of the preset measurement points. Impedance of the renewable energy power generation device after being decoupled from the measurement device and the impedance of the power grid, is calculated.
    Type: Grant
    Filed: June 12, 2024
    Date of Patent: October 15, 2024
    Assignee: CHINA ELECTRIC POWER RESEARCH INSTITUTE
    Inventors: Weisheng Wang, Guanghui Li, Guoqing He, Yuntao Xiao, Yu Lei, Zixuan Guo, Shuanglei Feng, Caiyun Gao, Junhua Ma, Keke Liu, Liping Gao, Ni Zhen, Yuye Li, Yuqi Duan, Fangfang Yu
  • Publication number: 20240316295
    Abstract: The present disclosure may provide an atomizer and an electronic atomization device. The atomizer may include a shell, a heating assembly, a lid, a base, and a first sealing component. The shell defines a liquid cavity and a smoke outlet. The heating assembly may heat and atomize the liquid into a smoke. The lid and the base may be provided to fix the heating assembly therebetween. The lid defines a liquid inlet communicating with the liquid cavity, and the liquid may flow through to reach the heating assembly. The atomizer may define an air entering hole, such that external air may enter the device through the hole to drive smoke to flow. The first sealing component may be engaged between the lid and the heating assembly, contacting both at the same time and defining air guiding channels to guide the air to flow into the liquid cavity.
    Type: Application
    Filed: June 4, 2024
    Publication date: September 26, 2024
    Inventors: Guanghui Li, Weidong Pan, Kui Li, Zhenyu Wu
  • Patent number: 12042601
    Abstract: The present disclosure may provide an atomizer and an electronic atomization device. The atomizer may include a shell, a heating assembly, a lid, a base, and a first sealing component. The shell defines a liquid cavity and a smoke outlet. The heating assembly may heat and atomize the liquid into a smoke. The lid and the base may be provided to fix the heating assembly therebetween. The lid defines a liquid inlet communicating with the liquid cavity, and the liquid may flow through to reach the heating assembly. The atomizer may define an air entering hole, such that external air may enter the device through the hole to drive smoke to flow. The first sealing component may be engaged between the lid and the heating assembly, contacting both at the same time and defining air guiding channels to guide the air to flow into the liquid cavity.
    Type: Grant
    Filed: September 6, 2022
    Date of Patent: July 23, 2024
    Assignee: Shenzhen Smoore Technology Limited
    Inventors: Guanghui Li, Weidong Pan, Kui Li, Zhenyu Wu
  • Publication number: 20240085303
    Abstract: A method for determining the pore size and pore size distribution of a filtration membrane comprises: selecting a group of fluorescent pellets having different diameters and emission wavelengths as a reference; plotting the standard curve between the concentration and fluorescence intensity for each fluorescent pellet at its emission wavelength; uniformly dispensing a group of fluorescent pellets as a reference substance in water to prepare a mixed suspension of which the mass concentration of each fluorescent pellet; using the filter membrane to be tested to perform one-time filtration on the mixed suspension prepared, then performing fluorescence detection on the obtained filtrate, calculating the concentration of each fluorescent pellet in the filtrate the retention rate of the filtration membrane to be tested for each fluorescent pellet; and calculating the pore size and pore size distribution of the filter membrane to be tested accordingly.
    Type: Application
    Filed: April 27, 2021
    Publication date: March 14, 2024
    Inventors: Jinjie WANG, Guanghui LI, Pinhua RAO, Jian GUO, Junwei ZHANG, Jiaying ZHU
  • Patent number: 11888342
    Abstract: An electric system has an input terminal to receive an input voltage, a system output terminal to provide a system voltage, and N charging units for charging N loads respectively. The electric system has an input switch coupled between the input terminal and a first terminal, a switching circuit coupled between the first terminal and the system output terminal. The switching circuit converts the a boost output voltage at the first terminal to the system voltage, or converts the system voltage to the boost output voltage. The electric system further has a voltage control module having N input terminals coupled to the N charging units respectively, the voltage control module senses N charging currents passing through the N charging units respectively, and adjusts the boost output voltage based on the N charging currents.
    Type: Grant
    Filed: December 29, 2020
    Date of Patent: January 30, 2024
    Assignee: Monolithic Power Systems, Inc.
    Inventors: Yuncong Jiang, Christian Sporck, Guanghui Li