Patents by Inventor Guanghui Li

Guanghui Li has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 12171538
    Abstract: A three-dimensional (3D) magnetic particle imaging (MPI) method and system without rotating a field-free line (FFL) are disclosed. In accordance with the method, an FFL is generated such that magnetic particles in a region far from the FFL enter a magnetic saturation state. Further, a non-uniform mixed-frequency excitation magnetic field parallel to the FFL is applied to generate intermodulation response signals. In addition, the intermodulation response signals are acquired, amplified and filtered. Moreover, the intermodulation response signals are transmitted to a digital signal processing unit and an image reconstruction unit, and an encoding matrix is constructed. Additionally, a one-dimensional (1D) concentration distribution of the magnetic particles is reconstructed based on the encoding matrix and an actually measured voltage signal. The FFL is driven for line-by-line scanning along a vertical plane of the FFL, thereby achieving 3D imaging.
    Type: Grant
    Filed: July 3, 2024
    Date of Patent: December 24, 2024
    Assignee: Beihang University
    Inventors: Jie Tian, Yanjun Liu, Yu An, Guanghui Li
  • Publication number: 20240368264
    Abstract: An anti-TSLP nanobody and a use thereof are provided. A coding sequence encoding the anti-TSLP nanobody, corresponding expression vector and host cell capable of expressing the nanobody, and a method for producing the anti-TSLP nanobody are also provided. The anti-TSLP nanobody has a good TSLP/TSLPR blocking activity and is expressed using pichia pastoris. Its fermenter expression yield can reach 17-23 g/L.
    Type: Application
    Filed: May 16, 2022
    Publication date: November 7, 2024
    Inventors: Yakun WAN, Guanghui LI, Min ZHU, Junwei GAI, Xiaoning SHEN
  • Publication number: 20240349813
    Abstract: An atomizer includes: a liquid storage room for storing liquid aerosol generation substrate; an atomization main body having an atomization assembly, the atomization assembly including a liquid absorbing surface in liquid guide communication with the liquid storage room; and at least one vent channel having a vent tube provided on an inner wall surface of the liquid storage room, the vent tube including a vent opening that is away from the inner wall surface and/or the liquid absorbing surface.
    Type: Application
    Filed: June 28, 2024
    Publication date: October 24, 2024
    Inventors: Guanghui LI, Boxue GONG
  • Patent number: 12117473
    Abstract: A method and system for measuring broadband impedance of a renewable energy power generation device. A voltage disturbance is injected into the renewable energy power generation device by using a disturbance injection device, and three-phase voltage and three-phase current of each of preset measurement points are acquired. Relevant variables before the renewable energy power generation device is decoupled from a measurement device and impedance of a power grid, are calculated according to the three-phase voltage and the three-phase current of each of the preset measurement points. Impedance of the renewable energy power generation device after being decoupled from the measurement device and the impedance of the power grid, is calculated.
    Type: Grant
    Filed: June 12, 2024
    Date of Patent: October 15, 2024
    Assignee: CHINA ELECTRIC POWER RESEARCH INSTITUTE
    Inventors: Weisheng Wang, Guanghui Li, Guoqing He, Yuntao Xiao, Yu Lei, Zixuan Guo, Shuanglei Feng, Caiyun Gao, Junhua Ma, Keke Liu, Liping Gao, Ni Zhen, Yuye Li, Yuqi Duan, Fangfang Yu
  • Publication number: 20240316295
    Abstract: The present disclosure may provide an atomizer and an electronic atomization device. The atomizer may include a shell, a heating assembly, a lid, a base, and a first sealing component. The shell defines a liquid cavity and a smoke outlet. The heating assembly may heat and atomize the liquid into a smoke. The lid and the base may be provided to fix the heating assembly therebetween. The lid defines a liquid inlet communicating with the liquid cavity, and the liquid may flow through to reach the heating assembly. The atomizer may define an air entering hole, such that external air may enter the device through the hole to drive smoke to flow. The first sealing component may be engaged between the lid and the heating assembly, contacting both at the same time and defining air guiding channels to guide the air to flow into the liquid cavity.
    Type: Application
    Filed: June 4, 2024
    Publication date: September 26, 2024
    Inventors: Guanghui Li, Weidong Pan, Kui Li, Zhenyu Wu
  • Patent number: 12042601
    Abstract: The present disclosure may provide an atomizer and an electronic atomization device. The atomizer may include a shell, a heating assembly, a lid, a base, and a first sealing component. The shell defines a liquid cavity and a smoke outlet. The heating assembly may heat and atomize the liquid into a smoke. The lid and the base may be provided to fix the heating assembly therebetween. The lid defines a liquid inlet communicating with the liquid cavity, and the liquid may flow through to reach the heating assembly. The atomizer may define an air entering hole, such that external air may enter the device through the hole to drive smoke to flow. The first sealing component may be engaged between the lid and the heating assembly, contacting both at the same time and defining air guiding channels to guide the air to flow into the liquid cavity.
    Type: Grant
    Filed: September 6, 2022
    Date of Patent: July 23, 2024
    Assignee: Shenzhen Smoore Technology Limited
    Inventors: Guanghui Li, Weidong Pan, Kui Li, Zhenyu Wu
  • Publication number: 20240085303
    Abstract: A method for determining the pore size and pore size distribution of a filtration membrane comprises: selecting a group of fluorescent pellets having different diameters and emission wavelengths as a reference; plotting the standard curve between the concentration and fluorescence intensity for each fluorescent pellet at its emission wavelength; uniformly dispensing a group of fluorescent pellets as a reference substance in water to prepare a mixed suspension of which the mass concentration of each fluorescent pellet; using the filter membrane to be tested to perform one-time filtration on the mixed suspension prepared, then performing fluorescence detection on the obtained filtrate, calculating the concentration of each fluorescent pellet in the filtrate the retention rate of the filtration membrane to be tested for each fluorescent pellet; and calculating the pore size and pore size distribution of the filter membrane to be tested accordingly.
    Type: Application
    Filed: April 27, 2021
    Publication date: March 14, 2024
    Inventors: Jinjie WANG, Guanghui LI, Pinhua RAO, Jian GUO, Junwei ZHANG, Jiaying ZHU
  • Patent number: 11888342
    Abstract: An electric system has an input terminal to receive an input voltage, a system output terminal to provide a system voltage, and N charging units for charging N loads respectively. The electric system has an input switch coupled between the input terminal and a first terminal, a switching circuit coupled between the first terminal and the system output terminal. The switching circuit converts the a boost output voltage at the first terminal to the system voltage, or converts the system voltage to the boost output voltage. The electric system further has a voltage control module having N input terminals coupled to the N charging units respectively, the voltage control module senses N charging currents passing through the N charging units respectively, and adjusts the boost output voltage based on the N charging currents.
    Type: Grant
    Filed: December 29, 2020
    Date of Patent: January 30, 2024
    Assignee: Monolithic Power Systems, Inc.
    Inventors: Yuncong Jiang, Christian Sporck, Guanghui Li
  • Publication number: 20230399395
    Abstract: An anti-IL5 nanoantibody, and a coding sequence for coding the anti-IL5 nanoantibody, a corresponding expression vector, a host cell capable of expressing the anti-IL5 nanoantibody, and a method for producing the anti-IL5 nanoantibody are provided. The nanoantibody can specifically recognize IL5 from humans and cynomolgus monkeys, does not recognize IL5 from mice, and has a good binding activity. The nanoantibody has a good IL5/IL5R blocking activity. The blocking activity is obviously superior to that of a control antibody Nucala. The nanoantibody can effectively inhibit the proliferation of TF-1 cells induced by IL5, and the inhibition activity thereof is superior to that of the control antibody Nucala. The expression yield of the nanoantibody in Pichia pastoris can reach 13 g/L, and the purity of target protein expressed in the supernatant is high.
    Type: Application
    Filed: September 23, 2021
    Publication date: December 14, 2023
    Inventors: Yakun WAN, Min ZHU, Junwei GAI, Guanghui LI, Xiaoning SHEN
  • Publication number: 20230380506
    Abstract: A vaporizer includes: a vaporization base; a rotary support; and a heating structure. The rotary support is located in the vaporization base and rotatable relative to the vaporization base. The vaporization base has a first liquid flowing hole and a first air outlet hole. The rotary support has a vaporization cavity and a second liquid flowing hole, a first air inlet hole, and a second air outlet hole that are all in communication with the vaporization cavity. The heating structure is fixed in the vaporization cavity. When the rotary support is located in a first orientation relative to the vaporization base, the first liquid flowing hole is in communication with the second liquid flowing hole to form a liquid flowing channel, the first air inlet hole is in communication with an outside, and the first air outlet hole is in communication with the second air outlet hole.
    Type: Application
    Filed: May 26, 2023
    Publication date: November 30, 2023
    Inventors: Xingxing YANG, Guanghui LI, Hu JIN
  • Publication number: 20230363455
    Abstract: A heating body for an electronic vaporization device having an aerosol-generation substrate is disclosed. The heating body comprises a dense substrate comprising a liquid absorbing surface and a vaporization surface arranged opposite to each other. The dense substrate further comprises a plurality of micropores arranged through the liquid absorbing surface and the vaporization surface. The vaporization surface is a wetting structure that is surface treated. The wetting structure is in communication with the plurality of micropores in a liquid guiding manner.
    Type: Application
    Filed: December 30, 2022
    Publication date: November 16, 2023
    Inventors: Yueyang ZHAO, Ming LV, Biao ZHANG, Wenyuan FAN, Guanghui LI
  • Publication number: 20230337748
    Abstract: A vaporizer includes: a vaporization sleeve having a liquid storage cavity and a mounting cavity; a mounting base arranged in the mounting cavity and forming a vaporization cavity, an air inlet channel and an air outlet channel being in communication with the vaporization cavity; a vaporization core mounted in the vaporization cavity; and a fine groove provided on an inner wall of the air inlet channel, the fine groove buffering liquid entering the air inlet channel.
    Type: Application
    Filed: June 28, 2023
    Publication date: October 26, 2023
    Inventors: Zhouwei CHEN, Chao ZHANG, Guanghui LI
  • Patent number: 11776174
    Abstract: A fluorescence molecular tomography reconstruction method includes: obtaining an MPI three-dimensional tomographic image, a body surface near-infrared fluorescence two-dimensional image, and a CT image; constructing an SIS capable of accommodating the ROI, and discretizing the SIS by using a finite element method; performing data mapping to obtain detected surface fluorescence signals, a prior of the anatomical structure of tissues and organs around the tumor and a prior of the tumor; performing forward model calculation to obtain a system matrix and constructing an objective function; iteratively solving the objective function based on the Laplacian regularization matrix to obtain a fluorescence molecular tomography reconstruction result; the present invention adopts MPI to guide the FMT, achieving complete morphology and structure, clear tissue edges, and high accuracy of spatial position.
    Type: Grant
    Filed: February 20, 2023
    Date of Patent: October 3, 2023
    Inventors: Jie Tian, Yu An, Guanghui Li, Yang Du, Daxiang Yan, Jiaqian Li
  • Publication number: 20230218008
    Abstract: A vaporization assembly includes: a vaporization sleeve having a liquid storage cavity for storing liquid; and a mounting base embedded in the vaporization sleeve, a first liquid flowing channel and a second liquid flowing channel being provided in the mounting base in a direction facing the liquid storage cavity. In the first liquid flowing channel and the second liquid flowing channel, a plurality of guide grooves are provided only on a wall surface of the first liquid flowing channel so as to cause the first liquid flowing channel and the second liquid flowing channel to be asymmetrical in structure.
    Type: Application
    Filed: February 27, 2023
    Publication date: July 13, 2023
    Inventors: Guilin LEI, Boxue GONG, Zhouwei CHEN, Guanghui LI
  • Publication number: 20230210175
    Abstract: A vaporizer includes: a liquid storage tank for storing liquid; a mounting base including a leaked liquid buffer structure having a capillary force; and a vaporization core including a porous substrate and a heating element, the porous substrate being in fluid communication with the liquid storage tank and absorbing liquid from the liquid storage tank through a capillary force, the heating element heating and vaporizing the liquid of the porous substrate. The vaporization core is located between the liquid storage tank and the leaked liquid buffer structure. The leaked liquid buffer structure abuts the porous substrate and receives the liquid overflowed from the porous substrate.
    Type: Application
    Filed: March 10, 2023
    Publication date: July 6, 2023
    Inventors: Guilin LEI, Boxue GONG, Zhouwei CHEN, Guanghui LI
  • Publication number: 20230210183
    Abstract: A heating assembly for a vaporizer is disclosed. The heating assembly includes a first substrate and a second substrate. The first substrate includes a first surface and a second surface arranged opposite to each other. The first surface is a liquid absorbing surface. The first substrate includes a plurality of first micropores configured to guide an aerosol-generation substrate from the liquid absorbing surface to the second surface. The second substrate includes a third surface and a fourth surface arranged opposite to each other. The fourth surface is a vaporization surface. The second surface and the third surface are arranged opposite to each other.
    Type: Application
    Filed: December 30, 2022
    Publication date: July 6, 2023
    Inventors: Yueyang ZHAO, Ming LV, Guanghui LI, Biao ZHANG
  • Publication number: 20230122358
    Abstract: A vaporizer for vaporizing e-liquid includes: a liquid storage cavity for storing the e-liquid; a mounting base including a housing and a partition plate arranged in the housing, the partition plate having a through hole, and the through hole being in communication with the liquid storage cavity; a vaporization core mounted in the mounting base to heat and vaporize the e-liquid; a seal member arranged between the separating plate and the vaporization core, the seal member including an opening that is in communication with the through hole for the e-liquid to enter the vaporization core through the opening; and at least one vent groove between the mounting base and the seal member, the at least one vent groove being in communication with the liquid storage cavity and external air.
    Type: Application
    Filed: November 11, 2022
    Publication date: April 20, 2023
    Inventors: Guanghui LI, Guilin LEI, Yajun XIE, Zhouwei CHEN
  • Patent number: 11564417
    Abstract: A heating assembly, an atomizer and an electronic atomizing device are disclosed. The heating assembly includes a chassis and a heating component. The chassis may include a first wall having a top surface and a bottom surface opposite to the top surface, the first wall defining an air vent extending through the bottom surface, an air entering plate being connected with the first wall and covering the air vent, the air entering plate defining at least one air entering hole communicating with the installation space and the air vent, wherein the first wall and the second wall define the installation space. A heating component may be disposed in the installation space, a length of the at least one air vent is greater than that of the air entering hole in a direction from the bottom surface to the top surface.
    Type: Grant
    Filed: July 8, 2019
    Date of Patent: January 31, 2023
    Assignee: SHENZHEN SMOORE TECHNOLOGY LIMITED
    Inventors: Guanghui Li, Weidong Pan
  • Publication number: 20220409832
    Abstract: The present disclosure may provide an atomizer and an electronic atomization device. The atomizer may include a shell, a heating assembly, a lid, a base, and a first sealing component. The shell defines a liquid cavity and a smoke outlet. The heating assembly may heat and atomize the liquid into a smoke. The lid and the base may be provided to fix the heating assembly therebetween. The lid defines a liquid inlet communicating with the liquid cavity, and the liquid may flow through to reach the heating assembly. The atomizer may define an air entering hole, such that external air may enter the device through the hole to drive smoke to flow. The first sealing component may be engaged between the lid and the heating assembly, contacting both at the same time and defining air guiding channels to guide the air to flow into the liquid cavity.
    Type: Application
    Filed: September 6, 2022
    Publication date: December 29, 2022
    Inventors: Guanghui Li, Weidong Pan, Kui Li, Zhenyu Wu
  • Patent number: 11471625
    Abstract: The present disclosure may provide an atomizer and an electronic atomization device. The atomizer may include a shell, a heating assembly, a lid, a base, and a first sealing component. The shell defines a liquid cavity and a smoke outlet. The heating assembly may heat and atomize the liquid into a smoke. The lid and the base may be provided to fix the heating assembly therebetween. The lid defines a liquid inlet communicating with the liquid cavity, and the liquid may flow through to reach the heating assembly. The atomizer may define an air entering hole, such that external air may enter the device through the hole to drive smoke to flow. The first sealing component may be engaged between the lid and the heating assembly, contacting both at the same time and defining air guiding channels to guide the air to flow into the liquid cavity.
    Type: Grant
    Filed: November 21, 2019
    Date of Patent: October 18, 2022
    Assignee: SHENZHEN SMOORE TECHNOLOGY LIMITED
    Inventors: Guanghui Li, Weidong Pan, Kui Li, Zhenyu Wu