Abstract: The present invention relates to a compound represented by general formula (I) or a stereoisomer, a tautomer, a deuterated substance, a solvate, a prodrug, a metabolite and a pharmaceutically acceptable salt or eutectic crystal thereof, an intermediate thereof, and a use of the compound in METTL3-related diseases such as cancer.

Abstract: Disclosed is a biped robot and multi-configuration robot capable of being spliced autonomously, and a control method of the multi-configuration robot. The biped robot comprises a torso, arms, legs, a tolerance docking sleeve, and a torso docking device. The arms are correspondingly arranged at the left and right sides of the torso, and two legs are arranged at the lower side of the torso. The tolerance docking sleeve is movably arranged at the rear side of the torso through a base, and the torso docking device is fixed to the front side of the torso. Single biped robots in the present disclosure can form a multi-configuration legged combined body in a self-organization and reconstruction mode so as to achieve bipedal, quadrupedal, hexapodal and other multi-legged configurations. The motion stability and the load capacity of the legged robot are improved through the splicing combination of the modular legged robots.

Abstract: A method for using a laser device includes: dividing laser devices into a first laser group and a second laser group, and turning on the laser device in the first laser group and processing the pole sheet; when any temperature value of a galvanometer and a field lens of the laser device in the first laser group reaches a set value, turning off the laser device in the first laser group, and turning on the laser device in the second laser group to continue processing the pole sheet; when any temperature value of the galvanometer and field lens of the laser device in the second laser group reaches the set value, turning off the laser device in the second laser group, and turning on the laser device in the first laser group to continue processing the pole sheet.

Abstract: Compounds having formula (I)-(IX), and enantiomers, and diastereomers, stereoisomers, pharmaceutically acceptable salts and prodrugs thereof, are useful as kinase modulators, including RIPK1 modulation. All the variables are as defined herein.

Abstract: The present disclosure provides an image processing method, apparatus and device, the method includes: acquiring a visible light image and a fluorescence image corresponding to a designated location inside a target object, where the designated location inside the target object includes diseased tissue and normal tissue; determining a to-be-cut boundary corresponding to the diseased tissue from a to-be-detected image, where the to-be-detected image is the fluorescence image or a fused image of the visible light image and the fluorescence image; and generating a target image, the target image includes the visible light image and the to-be-cut boundary.

Abstract: Compounds having formula (I), and enantiomers, and diastereomers, stereoisomers, pharmaceutically-acceptable salts thereof, are useful as kinase modulators, including RIPK1 modulation. All the variables are as defined herein.

Abstract: Compounds having formula (I), and enantiomers, and diastereomers, stereoisomers, pharmaceutically-acceptable salts thereof, (I) are useful as kinase modulators, including RIPK1 modulation. All the variables are as defined herein.

Abstract: Compounds having formula (I)-(IX), and enantiomers, and diastereomers, stereoisomers, pharmaceutically acceptable salts and prodrugs thereof, are useful as kinase modulators, including RIPK1 modulation. All the variables are as defined herein.

Abstract: A sensor control method includes: obtaining first indication information, where the first indication information indicates a first scenario; determining a configuration parameter of at least one sensor based on the first indication information, where the configuration parameter is corresponding to the first scenario; and sending the configuration parameter to the at least one sensor. The sensor control method may be applied to automatic driving or intelligent driving, and may be specifically applied to assisted driving or unmanned driving. The sensor can be flexibly controlled through configurable parameters of sensors such as radar or a camera.

Abstract: A multi-GPU-based image rendering method includes: acquiring a target image, and detecting first rendering durations for different number of available devices to render the target image, where the available devices are GPU devices for image rendering; comparing the first rendering durations corresponding to different number of available devices, and acquiring the available devices corresponding to a minimum one of the first rendering durations as target devices; dividing the target image according to the target devices and a second rendering duration to obtain second images, where the second rendering duration is a duration required for a single target device to render the target image; rendering the second images based on rendering tasks in the target devices to obtain second image results, and combining the second image results to obtain a rendering image of the target image, where the rendering tasks are configured to render the second images.

Abstract: Embodiments of the present disclosure provide a data transmission method and apparatus. The method includes: receiving, by user equipment UE, first synchronization source configuration information on a first carrier; determining, a first synchronization source based on the first synchronization source configuration information; determining that synchronization with the first synchronization source fails; determining a second synchronization source and a transmission resource; and transmitting data on a second carrier using the determined transmission resource and based on the second synchronization source, where the first synchronization source is used to provide the UE with a synchronization clock required for transmitting the data on the second carrier, and a frequency of the first carrier is different from a frequency of the second carrier.

Abstract: The present disclosure is generally directed to compounds which can inhibit AAK1 (adaptor associated kinase 1), compositions comprising such compounds, and methods for inhibiting AAK1.

Abstract: The disclosure belongs to a field of hydraulic equipment, and in particular to an anti-rolling damping device for floating wind turbines. The specific technical scheme: low ends of buoys are connected with an upper surface of a support plate through a damping assembly, and the damping assembly includes a piston cylinder fixedly arranged on the support plate, a piston plate is slidably arranged in the piston cylinder, a piston rod is arranged at one end of the piston plate far from the support plate, the piston rod extends out of the piston cylinder and is fixedly connected with the buoys, and a plurality of first through holes are arranged on a side wall of the piston cylinder near the lower part. The buoys sink with waves, and the piston plate slides downwards in the piston cylinder.

Abstract: Disclosed is a method for optimization design of an artificial reef structure. The method includes: arranging an artificial reef model to be tested on a test platform, testing a flow field to obtain flow field data and a pull force of an artificial reef, analyzing the flow field data to obtain a flow velocity reference point, and carrying out optimization analysis in combination with the flow field data and the pull force.

Abstract: Compounds having formula (I), and enantiomers, and diastereomers, stereoisomers, pharmaceutically-acceptable salts thereof, are useful as kinase modulators, including RIPK1 modulation. All the variables are as defined herein.

Abstract: A multi-GPU-based image rendering method and apparatus, and a readable storage medium are disclosed.

Abstract: The disclosure belongs to a field of hydraulic equipment, and in particular to an anti-rolling damping device for floating wind turbines. The specific technical scheme: low ends of buoys are connected with an upper surface of a support plate through a damping assembly, and the damping assembly includes a piston cylinder fixedly arranged on the support plate, a piston plate is slidably arranged in the piston cylinder, a piston rod is arranged at one end of the piston plate far from the support plate, the piston rod extends out of the piston cylinder and is fixedly connected with the buoys, and a plurality of first through holes are arranged on a side wall of the piston cylinder near the lower part. The buoys sink with waves, and the piston plate slides downwards in the piston cylinder.

Abstract: A sensor control method includes: obtaining first indication information, where the first indication information indicates a first scenario; determining a configuration parameter of at least one sensor based on the first indication information, where the configuration parameter is corresponding to the first scenario; and sending the configuration parameter to the at least one sensor. The sensor control method may be applied to automatic driving or intelligent driving, and may be specifically applied to assisted driving or unmanned driving. The sensor can be flexibly controlled through configurable parameters of sensors such as radar or a camera.

Abstract: The present disclosure is generally directed to compounds which can inhibit AAK1 (adaptor associated kinase 1), compositions comprising such compounds, and methods for inhibiting AAK1.

Abstract: Embodiments of the present disclosure provide a data transmission method and apparatus. The method includes: receiving, by user equipment UE, first synchronization source configuration information on a first carrier; determining, a first synchronization source based on the first synchronization source configuration information; determining that synchronization with the first synchronization source fails; determining a second synchronization source and a transmission resource; and transmitting data on a second carrier using the determined transmission resource and based on the second synchronization source, where the first synchronization source is used to provide the UE with a synchronization clock required for transmitting the data on the second carrier, and a frequency of the first carrier is different from a frequency of the second carrier.