Abstract: A polypeptide compound having a structure shown in formula I, or a stereoisomer, mixture or pharmaceutically acceptable salt thereof Experimental results show that the polypeptide compound can effectively exhibit high agonistic activity to GHSR-1a.

Abstract: The present invention discloses a method for manufacturing a low-carbon nitrogen-containing austenitic stainless steel bar, which sequentially includes the following steps: smelting, electroslag remelting and forging; in the electroslag remelting process, the steel ingot obtained in the smelting process is used as an electrode bar of an electroslag furnace, remelting with specific slag and crystallizing; in the forging process, forging the crystallized steel ingot into a material by a specific forging method; the specific slag comprises CaF2 (65-70%), Al2O3 (15-20%), CaO (5-10%) and MgO (2-5%) in percentage by weight; specific forging methods include upsetting-and-drawing and radial forging, wherein the upsetting-and-drawing includes: a pass deformation is less than 35%, a pass reduction is 50-80 mm, a pass heating temperature is 1130-1150° C., and a pass deformation method is ellipse-ellipse-circle.