Patents by Inventor Guangping Xia

Guangping Xia has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20230174608
    Abstract: The present invention provides a polypeptide derivative, or a modified derivative or salt thereof, and use of the polypeptide derivative, or the modified derivative or salt thereof. The polypeptide derivative, or the modified derivative or salt thereof comprises a polypeptide having the sequence of the following general formula I: general formula I: HX2QGTFTSDX10SKYLX15EX17X18AX20X21FX23AWLEX28X29X30, wherein the definitions of X2, X10, X15, X17, X18, X20, X21, X23, X28, X29, and X30 are consistent with those in the claims and description. The polypeptide derivatives of the present invention are dual agonists for GC/GLP-1 receptor, have a synergic effect on energy metabolism, can effectively reduce weight and improve a body fat level while reducing blood glucose, and have a potential application value in the field of treatment of metabolic diseases such as diabetes and obesity.
    Type: Application
    Filed: May 8, 2021
    Publication date: June 8, 2023
    Inventors: Yingmei Han, Wei Liu, Bingni Liu, Weiling Kong, Naxia Zhao, Guangping Xia, Qian Shang, Jing Jin, Xiaohua Kong, Yuquan Li, Songhui Wang
  • Patent number: 9989566
    Abstract: A method is disclosed for detecting power interruption duration of an electronic device. The method can include establishing a curve model of linearly synthesized values of temperature sensor readings versus time; after power-on, acquiring each of the initial temperature values by respective temperature sensors mounted on the electronic device, and transmitting the temperature initial values to a microprocessor; calculating a linearly synthesized value of the temperature sensor readings of the electronic device according to a power-on duration for this time and a stored curve model, and storing the linearly synthesized value of the temperature sensor readings as a basis for calculating the power interruption duration thereafter. When the electronic device is powered on again after power interruption, a linearly synthesized value of the temperature sensor readings according to the power-on time for this time can be calculated, and used for calculating the power interruption duration thereafter.
    Type: Grant
    Filed: October 24, 2014
    Date of Patent: June 5, 2018
    Assignees: METTLER TOLEDO (CHANGZHOU) PRECISION INSTRUMENT LTD., METTLER TOLEDO (CHANGZHOU) MEASUREMENT TECHNOLOGY LTD., METTLER TOLEDO (CHANGZHOU) SCALE & SYSTEM LTD.
    Inventors: Guojun Xie, Guangping Xia, Jingquan Yu
  • Publication number: 20150106048
    Abstract: A method is disclosed for detecting power interruption duration of an electronic device. The method can include establishing a curve model of linearly synthesized values of temperature sensor readings versus time; after power-on, acquiring each of the initial temperature values by respective temperature sensors mounted on the electronic device, and transmitting the temperature initial values to a microprocessor; calculating a linearly synthesized value of the temperature sensor readings of the electronic device according to a power-on duration for this time and a stored curve model, and storing the linearly synthesized value of the temperature sensor readings as a basis for calculating the power interruption duration thereafter. When the electronic device is powered on again after power interruption, a linearly synthesized value of the temperature sensor readings according to the power-on time for this time can be calculated, and used for calculating the power interruption duration thereafter.
    Type: Application
    Filed: October 24, 2014
    Publication date: April 16, 2015
    Inventors: Guojun XIE, Guangping Xia, Jingquan Yu
  • Patent number: 8835134
    Abstract: This invention provides a method for preparing cycloastragenol monoglucoside CMG (cycloastragenol-6-O-?-D-glucoside), comprising the steps of: a. using astragaloside IV or Astragali extracts prepared by a conventional method as raw materials and adding an appropriate solvent thereinto to form a raw material solution; b. adding hydrolase and allowing for hydrolysis at a constant temperature to obtain a hydrolysate; c. separating the hydrolysate with macroporous adsorption resin; and d. obtaining the product by purification and separation. The present invention further provides cycloastragenol-6-O-?-D-glucoside prepared according to the method of this invention as well as its use in the preparation of a medicament for treating cardiovascular diseases and pharmaceutical compositions comprising the same.
    Type: Grant
    Filed: September 8, 2008
    Date of Patent: September 16, 2014
    Assignee: Tianjin Institute of Pharmaceutical Research
    Inventors: Yingmei Han, Guangping Xia, Weiren Xu, Zhuanyou Zhao, Wulin Liu, Naxia Zhao, Peng Liu, Shijun Zhang, Xiaoli Fu, Yuli Wang, Weiting Wang, Lida Tang
  • Publication number: 20110218161
    Abstract: This invention provides a method for preparing cycloastragenol monoglucoside CMG (cycloastragenol-6-O-?-D-glucoside), comprising the steps of: a. using astragaloside IV or Astragali extracts prepared by a conventional method as raw materials and adding an appropriate solvent thereinto to form a raw material solution; b. adding hydrolase and allowing for hydrolysis at a constant temperature to obtain a hydrolysate; c. separating the hydrolysate with macroporous adsorption resin; and d. obtaining the product by purification and separation. The present invention further provides cycloastragenol-6-O-?-D-glucoside prepared according to the method of this invention as well as its use in the preparation of a medicament for treating cardiovascular diseases and pharmaceutical compositions comprising the same.
    Type: Application
    Filed: September 8, 2008
    Publication date: September 8, 2011
    Applicant: Tianjin Institute of Pharmaceutical Research
    Inventors: Yingmei Han, Guangping Xia, Weiren Xu, Zhuanyou Zhao, Wulin Liu, Naxia Zhao, Peng Liu, Shijun Zhang, Xiaoli Fu, Yuli Wang, Weiting Wang, Lida Tang