Abstract: The present invention provides a cochlear outer hair cell (OHC) regenerated by ectopic joint overexpression of Atoh1 and Ikzf2 and an application thereof. Specifically, the present invention provides an active ingredient combination capable of being used for regenerating a cochlear OHC, and a use thereof. The active ingredient combination comprises an Ikzf2 protein and an Atoh1 protein; and after the active ingredient combination is administered to a subject suffering from hearing impairment related to cochlear OHC degeneration and/or injury, hearing impairment can be alleviated by regenerating an OHC-like cell. A new method is provided for clinical treatment of hearing impairment.

Abstract: The present disclosure provides a gas analysis device and a method for detecting sample gas. The gas analysis device includes: an ion mobility spectrometer including an ion mobility tube, an ion gate, a plurality of electrodes, a suppression grid, and a Faraday plate sequentially disposed in the ion mobility tube, wherein the Faraday plate is configured to receive sample ions discharged from the suppression grid, and the Faraday plate is provided with a through hole; a mass spectrometer; a gate valve disposed between the Faraday plate and an ion inlet of the mass spectrometer; and a controller configured to control an opening or closing of the gate valve to allow the sample ions discharged from the suppression grid to flow into the mass spectrometer through the through hole of the Faraday plate when the gate valve is opened.

Abstract: Embodiments of the present disclosure provide a real-time calibration device, a real-time calibration method and a detection apparatus. The real-time calibration device is in fluid communication with a sample injection pipeline of the apparatus to be calibrated. The real-time calibration device is configured to release a trace amount of calibration agent molecules during a sample injection of the apparatus to be calibrated, so that the trace amount of calibration agent molecules and a sample entering the apparatus to be calibrated are mixed and together enter the apparatus to be calibrated, and information of the sample and the calibration agent is detected by the apparatus to be calibrated, thereby performing a calibration.

Abstract: Embodiments of the present disclosure provide an ion mobility spectrometer device. The ion mobility spectrometer device includes: an ion mobility tube, a sampling device, and a sampling and circulating gas path. The sampling device includes a solid sample desorption device and a gas sampling device. The solid sample desorption device is configured to process the solid sample into a first mixed gas containing the solid sample, and the gas sampling device is configured to process the gas sample into a second mixed gas containing the gas sample. The sampling and circulating gas path is configured to transfer the first mixed gas and/or the second mixed gas into the ion mobility tube for detection.

Abstract: Embodiments of the present disclosure provide a real-time calibration device, a real-time calibration method and a detection apparatus. The real-time calibration device is in fluid communication with a sample injection pipeline of the apparatus to be calibrated. The real-time calibration device is configured to release a trace amount of calibration agent molecules during a sample injection of the apparatus to be calibrated, so that the trace amount of calibration agent molecules and a sample entering the apparatus to be calibrated are mixed and together enter the apparatus to be calibrated, and information of the sample and the calibration agent is detected by the apparatus to be calibrated, thereby performing a calibration.

Abstract: Embodiments of the present disclosure provide an automatic calibration device for an ion migration spectrometer and an ion migration spectrometer. The automatic calibration device includes: a reservoir configured to store liquid calibration sample therein; and an automatic transfer portion communicated with the reservoir and configured to transfer the liquid calibration sample in the reservoir.

Abstract: Embodiments of the present disclosure provide an ion mobility spectrometer device. The ion mobility spectrometer device includes: an ion mobility tube, a sampling device, and a sampling and circulating gas path. The sampling device includes a solid sample desorption device and a gas sampling device. The solid sample desorption device is configured to process the solid sample into a first mixed gas containing the solid sample, and the gas sampling device is configured to process the gas sample into a second mixed gas containing the gas sample. The sampling and circulating gas path is configured to transfer the first mixed gas and/or the second mixed gas into the ion mobility tube for detection.

Abstract: Embodiments of the present disclosure provide an automatic calibration device for an ion migration spectrometer and an ion migration spectrometer. The automatic calibration device includes: a reservoir configured to store liquid calibration sample therein; and an automatic transfer portion communicated with the reservoir and configured to transfer the liquid calibration sample in the reservoir.