Patents by Inventor Guangwen Ren

Guangwen Ren has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Methods for inducing an immune response by administering activated mesenchymal stem cells
    Patent number: 11872250
    Abstract: The present invention provides methods or kits with inflammatory cytokines to pretreat 1-ISCs to augment their immune modulatory effect, in prevention and treatment of various diseases such as multiple sclerosis, arthritis, lupus, sepsis, hepatitis, cirrhosis, Parkinson's disease, chronic infections, and GvHD. The present invention relates to novel methods for enhancing the immunosuppressive or the immune stimulatory activities of mesenchymal stem cells (JvfSCs).
    Type: Grant
    Filed: January 15, 2021
    Date of Patent: January 16, 2024
    Assignee: RUTGERS, THE STATE UNIVERSITY OF NEW JERSEY
    Inventors: Yufang Shi, Guangwen Ren, Liying Zhang
  • METHODS FOR INDUCING AN IMMUNE RESPONSE
    Publication number: 20210236558
    Abstract: The present invention provides methods or kits with inflammatory cytokines to pretreat 1-ISCs to augment their immune modulatory effect, in prevention and treatment of various diseases such as multiple sclerosis, arthritis, lupus, sepsis, hepatitis, cirrhosis, Parkinson's disease, chronic infections, and GvHD. The present invention relates to novel methods for enhancing the immunosuppressive or the immune stimulatory activities of mesenchymal stem cells (JvfSCs).
    Type: Application
    Filed: January 15, 2021
    Publication date: August 5, 2021
    Applicant: Rutgers, The State University of New Jersey
    Inventors: Yufang Shi, Guangwen Ren, Liying Zhang
  • METHODS FOR ENHANCING IMMUNOSUPPRESSION
    Publication number: 20210213067
    Abstract: The present invention provides methods or kits with inflammatory cytokines to pretreat 1-ISCs to augment their immune modulatory effect, in prevention and treatment of various diseases such as multiple sclerosis, arthritis, lupus, sepsis, hepatitis, cirrhosis, Parkinson's disease, chronic infections, and GvHD. The present invention relates to novel methods for enhancing the immunosuppressive or the immune stimulatory activities of mesenchymal stem cells (JvfSCs).
    Type: Application
    Filed: January 15, 2021
    Publication date: July 15, 2021
    Applicant: Rutgers, The State University of New Jersey
    Inventors: Yufang Shi, Guangwen Ren, Liying Zhang
  • Methods of producing activated mesenchymal stem cells
    Patent number: 10898523
    Abstract: The present invention provides methods or kits with inflammatory cytokines to pretreat 1-ISCs to augment their immune modulatory effect, in prevention and treatment of various diseases such as multiple sclerosis, arthritis, lupus, sepsis, hepatitis, cirrhosis, Parkinson's disease, chronic infections, and GvHD. The present invention relates to novel methods for enhancing the immunosuppressive or the immune stimulatory activities of mesenchymal stem cells (JvfSCs).
    Type: Grant
    Filed: August 10, 2018
    Date of Patent: January 26, 2021
    Assignee: Rutgers, The State University of New Jersey
    Inventors: Yufang Shi, Guangwen Ren, Liying Zhang
  • METHODS OF PRODUCING ACTIVATED MESENCHYMAL STEM CELLS
    Publication number: 20190046577
    Abstract: The present invention provides methods or kits with inflammatory cytokines to pretreat 1-ISCs to augment their immune modulatory effect, in prevention and treatment of various diseases such as multiple sclerosis, arthritis, lupus, sepsis, hepatitis, cirrhosis, Parkinson's disease, chronic infections, and GvHD. The present invention relates to novel methods for enhancing the immunosuppressive or the immune stimulatory activities of mesenchymal stem cells (JvfSCs).
    Type: Application
    Filed: August 10, 2018
    Publication date: February 14, 2019
    Inventors: Yufang Shi, Guangwen Ren, Liying Zhang
  • Compositions for inducing or suppressing an immune response
    Patent number: 10046011
    Abstract: The present invention provides methods or kits with inflammatory cytokines to pretreat 1-ISCs to augment their immune modulatory effect, in prevention and treatment of various diseases such as multiple sclerosis, arthritis, lupus, sepsis, hepatitis, cirrhosis, Parkinson's disease, chronic infections, and GvHD. The present invention relates to novel methods for enhancing the immunosuppressive or the immune stimulatory activities of mesenchymal stem cells (JvfSCs).
    Type: Grant
    Filed: December 14, 2013
    Date of Patent: August 14, 2018
    Assignee: RUTGERS, THE STATE UNIVERSITY OF NEW JERSEY
    Inventors: Yufang Shi, Guangwen Ren, Liying Zhang
  • Method for attenuating immune response using mesenchymal stem cells and cytokines
    Patent number: 9301979
    Abstract: The present invention relates to a composition and methods of treatment for inflammation comprising of adult stem cells and inflammatory cytokines. The invention further relates to the treatment of inflammation associated with autoimmune disorders, allergies, sepsis, cancer as well as to preventing, reducing or treating transplant rejection and/or graft-versus-host disease (GvHD).
    Type: Grant
    Filed: February 6, 2014
    Date of Patent: April 5, 2016
    Assignee: RUTGERS, THE STATE UNIVERSITY OF NEW JERSEY
    Inventors: Yufang Shi, Liying Zhang, Guangwen Ren
  • METHODS MODULATING IMMUNOREGULATORY EFFECT OF STEM CELLS
    Publication number: 20150313946
    Abstract: The present invention provides methods or kits with inflammatory cytokines to pretreat 1-ISCs to augment their immune modulatory effect, in prevention and treatment of various diseases such as multiple sclerosis, arthritis, lupus, sepsis, hepatitis, cirrhosis, Parkinson's disease, chronic infections, and GvHD. The present invention relates to novel methods for enhancing the immunosuppressive or the immune stimulatory activities of mesenchymal stem cells (JvfSCs).
    Type: Application
    Filed: December 14, 2013
    Publication date: November 5, 2015
    Applicant: RUTGERS, THE STATE UNIVERSITY OF NEW JERSEY
    Inventors: Yufang SHI, Guangwen REN, Liying ZHANG
  • KIT CONTAINING STEM CELLS AND CYTOKINES FOR USE IN ATTENUATING IMMUNE RESPONSES
    Publication number: 20140154207
    Abstract: The present invention relates to a composition and methods of treatment for inflammation comprising of adult stem cells and inflammatory cytokines. The invention further relates to the treatment of inflammation associated with autoimmune disorders, allergies, sepsis, cancer as well as to preventing, reducing or treating transplant rejection and/or graft-versus-host disease (GvHD).
    Type: Application
    Filed: February 6, 2014
    Publication date: June 5, 2014
    Applicant: RUTGERS, THE STATE UNIVERSITY OF NEW JERSEY
    Inventors: Yufang Shi, Liying Zhang, Guangwen Ren
  • Kit containing stem cells and cytokines for use in attenuating immune responses
    Patent number: 8685728
    Abstract: The present invention relates to a composition and methods of treatment for inflammation comprising of adult stem cells and inflammatory cytokines. The invention further relates to the treatment of inflammation associated with autoimmune disorders, allergies, sepsis, cancer as well as to preventing, reducing or treating transplant rejection and/or graft-versus-host disease (GvHD).
    Type: Grant
    Filed: January 30, 2009
    Date of Patent: April 1, 2014
    Assignee: Rutgers The State University of New Jersey
    Inventors: Yufang Shi, Guangwen Ren, Liying Zhang
  • Method for modulating immune responses using stem cells and cytokines
    Publication number: 20090202479
    Abstract: The present invention relates to a composition and methods of treatment for inflammation comprising of adult stem cells and inflammatory cytokines. The invention further relates to the treatment of inflammation associated with autoimmune disorders, allergies, sepsis, cancer as well as to preventing, reducing or treating transplant rejection and/or graft-versus-host disease (GvHD).
    Type: Application
    Filed: January 30, 2009
    Publication date: August 13, 2009
    Inventors: Yufang Shi, Guangwen Ren, Liying Zhang