Patents by Inventor Guangzhao Mao

Guangzhao Mao has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Electrochemical deposition of nanowires on nanoparticles, lithographical patterns and electronic devices and their use as chemical sensors
    Patent number: 10890556
    Abstract: Materials and methods for generating nanowires are described. Krogmann salt potassium tetracyanoplatinate sesquihydrate (K(def)TCP) nanowires are synthesized as interconnects on metal lithographic patterns in which the K(def)TCP nanowires grow across the metal lines. The chemical sensing capability of the K(def)TCP chips is demonstrated by impedance measurements.
    Type: Grant
    Filed: November 9, 2017
    Date of Patent: January 12, 2021
    Assignee: WAYNE STATE UNIVERSITY
    Inventor: Guangzhao Mao
  • Compositions and methods relating to RAD6 inhibition
    Patent number: 10588985
    Abstract: Pharmaceutical compositions, methods of treatment of proliferative diseases and commercial packages are provided according to aspects of the present invention which relate to a first therapeutic agent coupled to a nanoparticle, wherein the first therapeutic agent is SMI #8 or SMI #9 a pharmaceutically acceptable salt, ester, amide, stereoisomer, hydrate, or derivative of either thereof. According to particular aspects, the SMI #8 or SMI #9 is conjugated to gold nanoparticles.
    Type: Grant
    Filed: September 2, 2016
    Date of Patent: March 17, 2020
    Assignee: Wayne State University
    Inventors: Malathy Shekhar, Guangzhao Mao, Yanhua Zhang
  • COMPOSITIONS AND METHODS RELATING TO RAD6 INHIBITION
    Publication number: 20180280535
    Abstract: Pharmaceutical compositions, methods of treatment of proliferative diseases and commercial packages are provided according to aspects of the present invention which relate to a first therapeutic agent coupled to a nanoparticle, wherein the first therapeutic agent is SMI#8 or SMI#9 a pharmaceutically acceptable salt, ester, amide, stereoisomer, hydrate, or derivative of either thereof. According to particular aspects, the SMI#8 or SMI#9 is conjugated to gold nanoparticles.
    Type: Application
    Filed: September 2, 2016
    Publication date: October 4, 2018
    Inventors: Malathy Shekhar, Guangzhao Mao, Yanhua Zhang
  • ELECTROCHEMICAL DEPOSITION OF NANOWIRES ON NANOPARTICLES, LITHOGRAPHICAL PATTERNS AND ELECTRONIC DEVICES AND THEIR USE AS CHEMICAL SENSORS
    Publication number: 20180128776
    Abstract: Materials and methods for generating nanowires are described. Krogmann salt potassium tetracyanoplatinate sesquihydrate (K(def)TCP) nanowires are synthesized as interconnects on metal lithographic patterns in which the K(def)TCP nanowires grow across the metal lines. The chemical sensing capability of the K(def)TCP chips is demonstrated by impedance measurements.
    Type: Application
    Filed: November 9, 2017
    Publication date: May 10, 2018
    Inventor: Guangzhao Mao
  • Transporter protein-coupled nanodevices for targeted drug delivery
    Patent number: 9649381
    Abstract: A tripartite nanodevice comprising a targeting portion, a carrier portion, and at least one molecule to be delivered is provided. In particular, a gold nanoparticle linked to a targeting protein and capable of delivering a stimulant for the treatment of respiratory or disease is described. A method of making and a method of using a device of this nature are also described.
    Type: Grant
    Filed: November 6, 2014
    Date of Patent: May 16, 2017
    Assignee: WAYNE STATE UNIVERSITY
    Inventors: Harry Goshgarian, Guangzhao Mao, Yanhua Zhang
  • TRANSPORTER PROTEIN-COUPLED NANODEVICES FOR TARGETED DRUG DELIVERY
    Publication number: 20150125926
    Abstract: A tripartite nanodevice comprising a targeting portion, a carrier portion, and at least one molecule to be delivered is provided. In particular, a gold nanoparticle linked to a targeting protein and capable of delivering a stimulant for the treatment of respiratory or disease is described. A method of making and a method of using a device of this nature are also described.
    Type: Application
    Filed: November 6, 2014
    Publication date: May 7, 2015
    Inventors: Harry Goshgarian, Guangzhao Mao, Yanhua Zhang
  • FORMATION OF A SUPRA-MONOLAYER NANOPATTERN AND ITS USES
    Publication number: 20140349889
    Abstract: The present disclosure discloses a method to prepare a supra-monolayer nanopattern and its uses.
    Type: Application
    Filed: December 11, 2012
    Publication date: November 27, 2014
    Applicant: WAYNE STATE UNIVERSITY
    Inventors: Guangzhao Mao, Daniel J. Sobczynski, Sunxi Wang, Juxhin Xhahysa, Pedram Jahanian
  • Particle-rod nanostructures
    Patent number: 8206824
    Abstract: A particle-rod nanostructure is disclosed. The nanostructure comprises an inorganic nanoparticle coated with a capping agent and an organic crystalline rod nucleated on the capped inorganic nanoparticle in a one-dimensional growth pattern.
    Type: Grant
    Filed: March 18, 2010
    Date of Patent: June 26, 2012
    Assignee: Wayne State University
    Inventors: Guangzhao Mao, Stephanie L. Brock, Dongzhong Chen, Ruomiao Wang, Indika U. Arachchige
  • PARTICLE-ROD NANOSTRUCTURES
    Publication number: 20100183875
    Abstract: A particle-rod nanostructure is disclosed. The nanostructure comprises an inorganic nanoparticle coated with a capping agent and an organic crystalline rod nucleated on the capped inorganic nanoparticle in a one-dimensional growth pattern.
    Type: Application
    Filed: March 18, 2010
    Publication date: July 22, 2010
    Applicant: WAYNE STATE UNIVERSITY
    Inventors: GUANGZHAO MAO, STEPHANIE L. BROCK, DONGZHONG CHEN, RUOMIAO WANG, INDIKA U. ARACHCHIGE
  • Particle-rod nano structures and method of forming same by spin coating
    Patent number: 7709054
    Abstract: A method of forming a particle-rod nanostructure is disclosed. The method comprises preparing a mixture comprising an inorganic nanoparticle and an organic molecule in a solvent. The method further comprises spin-coating the mixture to nucleate a crystal growth of the organic molecule on the inorganic nanoparticle deposited on a substrate, yielding the particle-rod nanostructure.
    Type: Grant
    Filed: July 14, 2006
    Date of Patent: May 4, 2010
    Assignee: Wayne State University
    Inventors: Guangzhao Mao, Stephanie L. Brock, Dongzhong Chen, Ruomiao Wang, Indika U. Arachchige
  • PARTICLE-ROD NANO STRUCTURES AND METHOD OF FORMING SAME BY SPIN COATING
    Publication number: 20100080899
    Abstract: A method of forming a particle-rod nanostructure is disclosed. The method comprises preparing a mixture comprising an inorganic nanoparticle and an organic molecule in a solvent. The method further comprises spin-coating the mixture to nucleate a crystal growth of the organic molecule on the inorganic nanoparticle deposited on a substrate, yielding the particle-rod nanostructure.
    Type: Application
    Filed: July 14, 2006
    Publication date: April 1, 2010
    Inventors: Guangzhao Mao, Stephanie L. Brock, Dongzhong Chen, Ruomiao Wang, Indika U. Arachchige