Patents by Inventor Guansong Wu

Guansong Wu has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Huperzine A derivatives, their preparation and their use
    Patent number: 5929084
    Abstract: The present invention relates to novel huperzine A derivatives of formula (II), wherein Y is ##STR1## or R" and Y together form .dbd.CH; R is (C.sub.1 -C.sub.5) alkyl, ##STR2## wherein n is 0 or 1, X is H, (C.sub.1 -C.sub.5) alkyl; (C.sub.1 -C.sub.5) alkyloxy; nitro, halogen, carboxy, alkyloxycarbonyl, hydroxymethyl, hydroxy, amino substituted by bis-(C.sub.1 -C.sub.5) alkyl; --(CH.sub.2).sub.m COOZ, wherein m=0-5, Z is H or (C.sub.1 -C.sub.5) alkyl; --CH.dbd.CH--G, wherein G is phenyl, furanyl, carboxy, alkyloxycarbonyl; and dihydro- or tetrahydro-pyridyl substituted by (C.sub.1 -C.sub.5) alkyl at the nitrogen atom; R' is H, (C.sub.1 -C.sub.5) alkyl, pyridoyl, benzoyl substituted by (C.sub.1 -C.sub.5) alkyloxy; R" is H or (C.sub.1 -C.sub.5) alkyl; processes for their use as acetylcholinesterase inhibitor.
    Type: Grant
    Filed: June 27, 1997
    Date of Patent: July 27, 1999
    Assignee: Shangahi Institute of Materia Medica Chinese Academy of Sciences
    Inventors: Dayuan Zhu, Xican Tang, Jinlai Lin, Cheng Zhu, Jingkang Shen, Guansong Wu, Shanhao Jiang, Takuji Yamaguchi, Kazuhiro Tanaka, Takeshi Wakamatsu, Hiroaki Nishimura