Patents by Inventor Guanzhang LI

Guanzhang LI has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20240052014
    Abstract: The present disclosure relates to a truncated body of IL7R?. The amino acid sequence of the truncated body of IL7R? s a sequence shown in SEQ ID NO. 1. A T cell expressing a chimeric antigen receptor containing the truncated body of IL7R? can effectively kill a tumor cell.
    Type: Application
    Filed: July 30, 2021
    Publication date: February 15, 2024
    Applicant: Beijing Neurosurgical Institute
    Inventors: Wei ZHANG, Tao JIANG, You ZHAI, Guanzhang LI
  • Publication number: 20230322940
    Abstract: The disclosure relates to an anti-CD44 single-chain antibody and use thereof in preparing a drug for treating a tumor. The amino acid sequence of the anti-CD44 single-chain antibody includes a sequence shown in SEQ ID NO. 1. T lymphocytes expressing the anti-CD44 single-chain antibody provided in the present disclosure can specifically kill CD44-positive tumor cells and have high specificity as well as strong killing ability.
    Type: Application
    Filed: July 30, 2021
    Publication date: October 12, 2023
    Applicant: Beijing Neurosurgical Institute
    Inventors: Wei ZHANG, Tao JIANG, You ZHAI, Guanzhang LI
  • Publication number: 20230310603
    Abstract: The disclosure relates to an anti-CD133 single-chain antibody. The amino acid sequence of the anti-CD133 single-chain antibody comprises a sequence shown in SEQ ID NO. 1. T lymphocytes expressing the anti-CD133 single-chain antibody can specifically kill CD133-positive tumor cells and have higher specificity and stronger killing ability.
    Type: Application
    Filed: July 30, 2021
    Publication date: October 5, 2023
    Applicant: Beijing Neurosurgical Institute
    Inventors: Wei ZHANG, Tao JIANG, You ZHAI, Guanzhang LI
  • Publication number: 20230295294
    Abstract: The disclosure relates to an anti-TIM3 single-chain antibody. The amino acid sequence of the anti-TIM3 single-chain antibody is a sequence shown in SEQ ID NO. 1. T lymphocytes expressing the anti-TIM3 single-chain antibody can effectively kill tumor cells.
    Type: Application
    Filed: July 30, 2021
    Publication date: September 21, 2023
    Applicant: Beijing Neurosurgical Institute
    Inventors: Wei ZHANG, Tao JIANG, You ZHAI, Guanzhang LI