Patents by Inventor Guanzhen WANG

Guanzhen WANG has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 11709123
    Abstract: A method for analyzing nucleated red blood cells in a blood sample includes obtaining fluorescence signals and scattered light signals of cells in a blood sample; classifying and counting ghost particles, white blood cells, and nucleated red blood cells in the blood sample according to the fluorescence signals and the scattered light signals; obtaining a characteristic value of a characteristic particle population related to the nucleated red blood cells; and ascertaining a final nucleated red blood cell detection result according to the classifying and counting result of the nucleated red blood cells and the characteristic value of the characteristic particle group.
    Type: Grant
    Filed: June 21, 2021
    Date of Patent: July 25, 2023
    Assignee: Shenzhen Mindray Bio-Medical Electronics Co., Ltd.
    Inventors: Guanzhen Wang, Bo Ye, Huan Qi
  • Patent number: 11609175
    Abstract: The present invention falls within the field of medical apparatuses. Disclosed are a method and a device for identifying platelet aggregation, and a flow cytometer, which are used for accurately giving an alarm about a platelet aggregation during blood cell analysis.
    Type: Grant
    Filed: December 18, 2019
    Date of Patent: March 21, 2023
    Assignee: SHENZHEN MINDRAY BIO-MEDICAL ELECTRONICS CO., LTD.
    Inventors: Guanzhen Wang, Bo Ye, Jiantao Di
  • Publication number: 20210318222
    Abstract: A blood cell parameter correction method includes: obtaining the optical signal information of the particles in the blood sample; according to the pulse width information in the optical signal information, dividing the particles in the blood sample to obtain particle distribution information; according to the preset correction rule, correcting the particle distribution information to obtain the corrected particle distribution information; wherein, the correction rule is related to the pulse width information in the optical signal information, and provided is also a blood sample analyzer executing the method, and storage medium storing the program executing the method.
    Type: Application
    Filed: June 23, 2021
    Publication date: October 14, 2021
    Inventors: Bo YE, Guanzhen WANG, Jin LI
  • Publication number: 20210318223
    Abstract: A method for analyzing nucleated red blood cells in a blood sample includes obtaining fluorescence signals and scattered light signals of cells in a blood sample; classifying and counting ghost particles, white blood cells, and nucleated red blood cells in the blood sample according to the fluorescence signals and the scattered light signals; obtaining a characteristic value of a characteristic particle population related to the nucleated red blood cells; and ascertaining a final nucleated red blood cell detection result according to the classifying and counting result of the nucleated red blood cells and the characteristic value of the characteristic particle group.
    Type: Application
    Filed: June 21, 2021
    Publication date: October 14, 2021
    Inventors: Guanzhen WANG, Bo YE, Huan QI
  • Patent number: 10983042
    Abstract: A cell analyzer and a sorting method for the cell analyzer are disclosed. Multiple optical signals generated by each of particles irradiated with light in a blood sample in a detection region are collected. The particles includes a first category of particles and a second category of particles. For each of the particles, Intensities of a first group of optical signals, which includes at least two optical signals selected from the multiple optical signals, and a pulse width of a second group of optical signals, which includes at least one optical signal selected from the multiple optical signals are acquired. For each of the particles, one or more reinforcement signals related to the particle are calculated based on an intensity of a first optical signal selected from the first group of optical signals and a pulse width of a second optical signal selected from the second group of optical signals, where the first optical signal is as same as or different from the second optical signal.
    Type: Grant
    Filed: February 26, 2020
    Date of Patent: April 20, 2021
    Assignee: Shenzhen Mindray Bio-Medical Electronics Co., Ltd
    Inventors: Bo Ye, Guanzhen Wang, Jiantao Di, Ying Zhang, Huan Qi
  • Patent number: 10883916
    Abstract: A cell analyzer and a sorting method for the cell analyzer are disclosed. Multiple optical signals generated by each of particles irradiated with light in a blood sample in a detection region are collected. The particles includes a first category of particles and a second category of particles. For each of the particles, Intensities of a first group of optical signals, which includes at least two optical signals selected from the multiple optical signals, and a pulse width of a second group of optical signals, which includes at least one optical signal selected from the multiple optical signals are acquired. For each of the particles, one or more reinforcement signals related to the particle are calculated based on an intensity of a first optical signal selected from the first group of optical signals and a pulse width of a second optical signal selected from the second group of optical signals, where the first optical signal is as same as or different from the second optical signal.
    Type: Grant
    Filed: February 26, 2020
    Date of Patent: January 5, 2021
    Assignee: Shenzhen Mindray Bio-Medical Electronics Co., Ltd.
    Inventors: Bo Ye, Guanzhen Wang, Jiantao Di, Ying Zhang, Huan Qi
  • Publication number: 20200191701
    Abstract: A cell analyzer and a sorting method for the cell analyzer are disclosed. Multiple optical signals generated by each of particles irradiated with light in a blood sample in a detection region are collected. The particles includes a first category of particles and a second category of particles. For each of the particles, Intensities of a first group of optical signals, which includes at least two optical signals selected from the multiple optical signals, and a pulse width of a second group of optical signals, which includes at least one optical signal selected from the multiple optical signals are acquired. For each of the particles, one or more reinforcement signals related to the particle are calculated based on an intensity of a first optical signal selected from the first group of optical signals and a pulse width of a second optical signal selected from the second group of optical signals, where the first optical signal is as same as or different from the second optical signal.
    Type: Application
    Filed: February 26, 2020
    Publication date: June 18, 2020
    Inventors: Bo YE, Guanzhen WANG, Jiantao DI, Ying ZHANG, Huan QI
  • Publication number: 20200191700
    Abstract: A cell analyzer and a sorting method for the cell analyzer are disclosed. Multiple optical signals generated by each of particles irradiated with light in a blood sample in a detection region are collected. The particles includes a first category of particles and a second category of particles. For each of the particles, Intensities of a first group of optical signals, which includes at least two optical signals selected from the multiple optical signals, and a pulse width of a second group of optical signals, which includes at least one optical signal selected from the multiple optical signals are acquired. For each of the particles, one or more reinforcement signals related to the particle are calculated based on an intensity of a first optical signal selected from the first group of optical signals and a pulse width of a second optical signal selected from the second group of optical signals, where the first optical signal is as same as or different from the second optical signal.
    Type: Application
    Filed: February 26, 2020
    Publication date: June 18, 2020
    Inventors: Bo YE, Guanzhen WANG, Jiantao DI, Ying ZHANG, Huan QI
  • Publication number: 20200132589
    Abstract: The present invention falls within the field of medical apparatuses. Disclosed are a method and a device for identifying platelet aggregation, and a flow cytometer, which are used for accurately giving an alarm about a platelet aggregation during blood cell analysis.
    Type: Application
    Filed: December 18, 2019
    Publication date: April 30, 2020
    Applicant: SHENZHEN MINDRAY BIO-MEDICAL ELECTRONICS CO., LTD.
    Inventors: Guanzhen WANG, Bo YE, Jiantao DI
  • Patent number: 10627332
    Abstract: A cell analyzer and a sorting method for the cell analyzer are disclosed. Multiple optical signals generated by each of particles irradiated with light in a blood sample in a detection region are collected. The particles includes a first category of particles and a second category of particles. For each of the particles, Intensities of a first group of optical signals, which includes at least two optical signals selected from the multiple optical signals, and a pulse width of a second group of optical signals, which includes at least one optical signal selected from the multiple optical signals are acquired. For each of the particles, one or more reinforcement signals related to the particle are calculated based on an intensity of a first optical signal selected from the first group of optical signals and a pulse width of a second optical signal selected from the second group of optical signals, where the first optical signal is as same as or different from the second optical signal.
    Type: Grant
    Filed: May 16, 2019
    Date of Patent: April 21, 2020
    Assignee: Shenzhen Mindray Bio-Medical Electronics Co., Ltd.
    Inventors: Bo Ye, Guanzhen Wang, Jiantao Di, Ying Zhang, Huan Qi
  • Publication number: 20190277746
    Abstract: A cell analyzer and a sorting method for the cell analyzer are disclosed. Multiple optical signals generated by each of particles irradiated with light in a blood sample in a detection region are collected. The particles includes a first category of particles and a second category of particles. For each of the particles, Intensities of a first group of optical signals, which includes at least two optical signals selected from the multiple optical signals, and a pulse width of a second group of optical signals, which includes at least one optical signal selected from the multiple optical signals are acquired. For each of the particles, one or more reinforcement signals related to the particle are calculated based on an intensity of a first optical signal selected from the first group of optical signals and a pulse width of a second optical signal selected from the second group of optical signals, where the first optical signal is as same as or different from the second optical signal.
    Type: Application
    Filed: May 16, 2019
    Publication date: September 12, 2019
    Inventors: Bo YE, Guanzhen WANG, Jiantao DI, Ying ZHANG, Huan QI
  • Patent number: 10330584
    Abstract: A cell analyzer and a particle sorting method and device are disclosed. The method comprises: acquiring a pulse width of at least one optical signal according to a detected optical signal, selecting at least one optical signal as a combined optical signal, and respectively calculating a signal intensity of the combined optical signal with the pulse width in a combinatorial way to obtain at least one reinforcement signal, where a difference between a first category of particles and a second categories of particles in the reinforcement signal is increased relative to a difference therebetween in the combined optical signal; and on the basis of the reinforcement signal and at least another signal, forming a new scatter diagram, where the at least another signal is one of other reinforcement signals and the optical signal, distinguishing the first category of particles from the second category of particles according to the new scatter diagram.
    Type: Grant
    Filed: August 11, 2017
    Date of Patent: June 25, 2019
    Assignee: Shenzhen Mindray Bio-Medical Electronics Co., Ltd.
    Inventors: Bo Ye, Guanzhen Wang, Jiantao Di, Ying Zhang, Huan Qi
  • Publication number: 20170350804
    Abstract: A cell analyzer and a particle sorting method and device are disclosed. The method comprises: acquiring a pulse width of at least one optical signal according to a detected optical signal, selecting at least one optical signal as a combined optical signal, and respectively calculating a signal intensity of the combined optical signal with the pulse width in a combinatorial way to obtain at least one reinforcement signal, where a difference between a first category of particles and a second categories of particles in the reinforcement signal is increased relative to a difference therebetween in the combined optical signal; and on the basis of the reinforcement signal and at least another signal, forming a new scatter diagram, where the at least another signal is one of other reinforcement signals and the optical signal, distinguishing the first category of particles from the second category of particles according to the new scatter diagram.
    Type: Application
    Filed: August 11, 2017
    Publication date: December 7, 2017
    Inventors: Bo YE, Guanzhen WANG, Jiantao DI, Ying ZHANG, Huan QI