Patents by Inventor Guanzheng Luo

Guanzheng Luo has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • KEY GENES, MICRORNAS, OTHER NON-CODING RNAS AND COMBINATION THEREOF FOR IDENTIFYING AND REGULATING THE PLURIPOTENT STATUS OF CELLS
    Publication number: 20130035241
    Abstract: Key genes, microRNAs, other non-coding RNAs and a combination thereof for identifying and regulating pluripotency of cells are provided. The key genes, microRNAs, other non-coding RNAs and a combination thereof are highly expressed in full pluripotent stem cells but are significantly suppressed or silenced in partially pluripotent stem cells. The genes, microRNAs and other non-coding RNAs are those of a chromosome imprinted Dlk1-Dio3 region located on the long arm of mouse chromosome 12, and are homologous genes, microRNAs and other non-coding RNAs having 70-100% homology with them in genomic syntenic regions of other mammals. Also provided are uses of the genes, microRNAs, other non-coding RNAs and combination thereof in identifying the pluripotent status of stem cells and regulating pluripotency of cells; in typing stem cells; regulating pluripotency of cells, pluripotent states and levels of cells; treating diseases; and developing drug targets for tumor treatment and antitumor drugs.
    Type: Application
    Filed: April 7, 2010
    Publication date: February 7, 2013
    Applicant: INSTITUTE OF ZOOLOGY, CHINESE ACADEMY OF SCIENCES
    Inventors: Qi Zhou, Xiujie Wang, Liu Wang, Lei Liu, Xiaoyang Zhao, Wei Yang, Guanzheng Luo, Zhuo LV, Qinyuan Zheng, Huajun Wu, Wei Li