Patents by Inventor Gudrun Werner

Gudrun Werner has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • HETEROCYCLIC AMIDES FOR USE AS PHARMACEUTICALS
    Publication number: 20100261758
    Abstract: Compounds of Formula (I) wherein R1 is aryl, cyclohexyl or heterocyclyl, or (C1-4)alkyl substituted by aryl, cyclohexyl or heterocyclyl, R2 is defined heterocyclyl, R3 is alkyl, aryl, cyclohexyl or heterocyclyl, or (C1-4)alkyl substituted by aryl, cyclohexyl or heterocyclyl, R4 is H or alkyl, or R3 and R4 together with the carbon atom to which they are attached are cycloalkyl fused with aryl, and their use as pharmaceuticals.
    Type: Application
    Filed: March 28, 2007
    Publication date: October 14, 2010
    Applicant: NOVARTIS AG
    Inventors: Luca Arista, Klemens Hogenauer, Niko Schmiedeberg, Gudrun Werner, Herbert Jaksche
  • N-arylsulfonyl-2,3-dihydro-1H-indoles and the use thereof as CCR9 inhibitors
    Patent number: 7781481
    Abstract: N-(benzenesulphonyl)-2,3-dihydro-1H-indols, wherein the indol is substituted by cyano, carboxy or alkylcarbonyloxy and their use as therapeutical agents.
    Type: Grant
    Filed: December 22, 2006
    Date of Patent: August 24, 2010
    Assignee: Novartis AG
    Inventors: Jose M. Carballido Herrera, Herbert Jaksche, Philipp Lehr, Gudrun Werner, Anthony Winiski
  • Inhibitors of CCR9 activity
    Patent number: 7759390
    Abstract: Compounds of formula I, wherein one of R1 and R2 is thienyl which is substituted by halogen and the other of R1 and R2 is substituted phenyl, wherein the substituents are as defined in the claims, with the proviso that the phenyl group is substituted by at least a cyano, carboxy or (C1-4)alkyloxycarbonyl group, are inhibitors of CCR9 activity and useful for therapeutic treatment.
    Type: Grant
    Filed: December 22, 2006
    Date of Patent: July 20, 2010
    Assignee: Novartis AG
    Inventors: Jose M. Carballido Herrera, Herbert Jaksche, Philipp Lehr, Gudrun Werner, Anthony Winiski
  • Receptor In Dendritic Cells
    Publication number: 20090317827
    Abstract: The present invention provides the use of GPR91 as a target in dendritic cells.
    Type: Application
    Filed: May 2, 2006
    Publication date: December 24, 2009
    Applicant: NOVARTIS AG
    Inventors: José M. Carballido Herrera, Günther Lametschwandtner, Gudrun Werner, Antal Rot
  • Receptor in Dendritic Cells
    Publication number: 20090215044
    Abstract: GPBAR1 for use as a target for selective inhibition of Th1 mediated immune responses.
    Type: Application
    Filed: June 9, 2006
    Publication date: August 27, 2009
    Inventor: Gudrun Werner
  • GPR18 as a Biomaker for TH1 Mediated Immune Response
    Publication number: 20090208997
    Abstract: The present invention provides the use of GPR18 in diseases or disorders mediated by Th1 cell activation.
    Type: Application
    Filed: May 2, 2006
    Publication date: August 20, 2009
    Inventors: José M. Carballido Herrera, Claudia Guenther, Günther Lametschwandtner, Gudrun Werner
  • Inhibitors of Ccr9 Activity
    Publication number: 20080312313
    Abstract: A compound of formula (I), wherein the residues have various meanings, useful as pharmaceuticals.
    Type: Application
    Filed: December 22, 2006
    Publication date: December 18, 2008
    Inventors: Jose M. Carballido Herrera, Herbert Jaksche, Philipp Lehr, Gudrun Werner, Anthony Winiski
  • Inhibitors of Ccr9 Activity
    Publication number: 20080300295
    Abstract: Compounds of formula I, wherein one of R1 and R2 is thienyl which is substituted by halogen and the other of R1 and R2 is substituted phenyl, wherein the substituents are as defined in the claims, with the proviso that the phenyl group is substituted by at least a cyano, carboxy or (C1-4)alkyloxycarbonyl group, are inhibitors of CCR9 activity and useful for therapeutic treatment.
    Type: Application
    Filed: December 22, 2006
    Publication date: December 4, 2008
    Inventors: Jose M. Carballido Herrera, Herbert Jaksche, Philipp Lehr, Gudrun Werner, Anthony Winiski
  • Inhibitors of Ccr9 Activity
    Publication number: 20080275114
    Abstract: Compounds of formula (I), in which R1 and R2 are independently a substituted phenyl group, where the substituents are as defined in the claims and with the proviso that at least one of the substituents is a cyano, carboxy or (C1-4)alkoxycarbonyl group, are inhibitors of CCR9 activity useful for therapeutic treatment, particularly of irritable bowel disease.
    Type: Application
    Filed: December 22, 2006
    Publication date: November 6, 2008
    Inventors: Jose M. Carballido Herrera, Herbert Jaksche, Philipp Lehr, Gudrun Werner, Anthony Winiski
  • Inhibitors of Ccr9 Activity
    Publication number: 20080269312
    Abstract: N-(benzenesulphonyl)-2,3-dihydro-1H-indols, wherein the indol is substituted by cyano, carboxy or alkylcarbonyloxy and their use as therapeutical agents.
    Type: Application
    Filed: December 12, 2006
    Publication date: October 30, 2008
    Inventors: Jose M. Carballido Herrera, Herbert Jaksche, Philipp Lehr, Gudrun Werner, Anthony Winiski
  • NOVEL G-PROTEIN COUPLED RECEPTORS AND DNA SEQUENCES THEREOF
    Publication number: 20070275391
    Abstract: The present invention relates to in particular immune modulatory polypeptides and polynucleotides, recombinant materials and methods for their production. Such polypeptides and polynucleotides are of interest in relation to methods of treatment of diseases whereby immune responses initiated by dendritic cells (DC), monocytes or lymphocytes, play a causal or contributory role.
    Type: Application
    Filed: September 29, 2006
    Publication date: November 29, 2007
    Inventors: Gung-Wei Chirn, Uwe Dengler, Frank Kolbinger, Quicheng Ma, Nanguneri Nirmala, Klaus Seuwen, Gudrun Werner
  • Organic compounds
    Publication number: 20060233818
    Abstract: Dendritic cell (DC) genes and polypeptides and their function in the identification of compounds which are (ant)agonists; and (ant)agonists to DC polypeptides.
    Type: Application
    Filed: June 19, 2006
    Publication date: October 19, 2006
    Inventors: Gudrun Werner, William Phares, Markus Jaritz, Hilmar Lapp, Frank Kalthoff
  • Novel g-protein coupled receptors and dna sequences thereof
    Publication number: 20050107589
    Abstract: The present invention relates to in particular immune modulatory polypeptides and polynucleotides, recombinant materials and methods for their production. Such polypeptides and polynucleotides are of interest in relation to methods of treatment of diseases whereby immune responses initiated by dendritic cells (DC), monocytes or lymphocytes, play a causal or contributory role.
    Type: Application
    Filed: December 16, 2002
    Publication date: May 19, 2005
    Inventors: Gung-Wei Chirn, Uwe Dengler, Frank Kolbinger, Qicheng Ma, Nanguneri Nirmala, Klaus Seuwen, Gudrun Werner
  • Organic compounds
    Publication number: 20030124575
    Abstract: Dendritic cell (DC) genes and polypeptide and their function in the identification of compounds which are (ant)agonists; and (ant)agonists to DC polypeptides.
    Type: Application
    Filed: November 19, 2002
    Publication date: July 3, 2003
    Inventors: Gudrun Werner, William F. Phares, Markus Jaritz, Hilmar Lapp, Frank Stephan Kalthoff