Abstract: A data transmission/reception system includes a data transmission circuit and a data reception circuit. The data transmission circuit includes a pattern detection unit configured to detect a pattern of data to be loaded on inner lines among a plurality of transmission lines and generate an inversion signal, and a transmission unit configured to transmit data to the plurality of transmission lines and the inversion signal to an inversion line, and invert some of the data to be loaded on the inner lines in response to the inversion signal. The data reception circuit is configured to invert the data inverted by the transmission unit among the data transferred to the plurality of transmission lines, in response to the inversion signal.