Patents by Inventor Guenther Bonn

Guenther Bonn has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20230361317
    Abstract: A redox flow battery, comprising a first electrolyte storage (1), a second electrolyte storage (2), an electrochemical cell connected to said first and second electrolyte storages (1, 2), wherein said electrochemical cell comprises a first half-cell and a second half-cell, wherein said first half-cell comprises a cathode (7), wherein said second half-cell comprises an anode (8), wherein said first and second half-cells are separated from each other by an ion exchange membrane (9), wherein said first electrolyte storage comprises an aqueous solution comprising an iron complex of a compound of formula I and stereoisomers of compound of formula I.
    Type: Application
    Filed: April 16, 2020
    Publication date: November 9, 2023
    Inventors: Philipp SCHRÖDER, Dagmar OBENDORF, Günther BONN, Noemi AGUILÓ-AGUAYO, Dorian RHOMBERG, Thomas DROZDZIK, Thomas BECHTOLD
  • Publication number: 20230285937
    Abstract: This invention employs solid phase extraction media and column methods to apply external and internal standards and compounds. Analytical standard or compounds including PFAS are adsorbed to a solid phase extraction media and are stored indefinitely. The standards or compounds remain stable on the solid phase extraction media without decomposing. The standards or compounds may be removed from the solid phase extraction media with an elution solvent or reagent.
    Type: Application
    Filed: May 16, 2023
    Publication date: September 14, 2023
    Inventors: Thomas Jakschitz, Douglas T. Gjerde, Guenther Bonn
  • Publication number: 20230278010
    Abstract: This invention employs columns and methods to apply external and internal standards and compounds. Analytical standard or compounds are adsorbed to a solid phase extraction media and are stored indefinitely. The standards or compounds remain stable on the solid phase extraction media without decomposing. The standards or compounds may be removed from the solid phase extraction media with a solvent.
    Type: Application
    Filed: May 8, 2023
    Publication date: September 7, 2023
    Inventors: Thomas Jakschitz, Douglas T. Gjerde, Guenther Bonn
  • Patent number: 11656209
    Abstract: This invention employs columns and methods to apply external and internal standards and compounds. Analytical standard or compounds are adsorbed to a solid phase extraction media and are stored indefinitely. The standards or compounds remain stable on the solid phase extraction media without decomposing. The standards or compounds may be removed from the solid phase extraction media with a solvent.
    Type: Grant
    Filed: October 24, 2019
    Date of Patent: May 23, 2023
    Inventors: Thomas Jakschitz, Douglas T. Gjerde, Guenther Bonn
  • Publication number: 20210072201
    Abstract: This invention employs columns and methods to apply external and internal standards and compounds. Analytical standard or compounds are adsorbed to a solid phase extraction media and are stored indefinitely. The standards or compounds remain stable on the solid phase extraction media without decomposing. The standards or compounds may be removed from the solid phase extraction media with a solvent.
    Type: Application
    Filed: October 24, 2019
    Publication date: March 11, 2021
    Inventors: Thomas Jakschitz, Douglas T. Gjerde, Guenther Bonn
  • Patent number: 9120847
    Abstract: The invention provides methods and apparatus for the selective isolation of phosphorylated and glycosylated proteins and their fragments. A lanthanide metal cation is used to precipitate proteins or protein fragments containing phospho groups and/or glyco groups. The sample preparation method can be used for many types of biological samples, including HeLa cells, food, and human cerebrospinal fluid. The proteins are isolated, recovered and ready for analysis by mass spectrometry or other analytical methods allowing detection limits down to the femtomole level. The method and apparatus are valuable tools in the field of protein analysis and diagnostics.
    Type: Grant
    Filed: January 17, 2013
    Date of Patent: September 1, 2015
    Inventors: Matthias Rainer, Douglas T. Gjerde, Guenther Bonn
  • Publication number: 20140329991
    Abstract: The invention provides methods and apparatus for the selective isolation of phosphorylated and glycosylated proteins and their fragments. A lanthanide metal cation is used to precipitate proteins or protein fragments containing phospho groups and/or glyco groups. The sample preparation method can be used for many types of biological samples, including HeLa cells, food, and human cerebrospinal fluid. The proteins are isolated, recovered and ready for analysis by mass spectrometry or other analytical methods allowing detection limits down to the femtomole level. The method and apparatus are valuable tools in the field of protein analysis and diagnostics.
    Type: Application
    Filed: January 17, 2013
    Publication date: November 6, 2014
    Inventors: Matthias Rainer, Fabio Polato, Douglas T. Gjerde, Guenther Bonn
  • Patent number: 8835612
    Abstract: The invention provides methods and apparatus for the selective isolation of phosphorylated and glycosylated proteins and their fragments. Metal cation is used to precipitate proteins or protein fragments containing phospho groups and/or glyco groups. The sample preparation method can be used for several types of biological samples, including HeLa cells, food, and human cerebrospinal fluid. The proteins are isolated, recovered and ready for analysis by mass spectrometry or other analytical methods allowing detection limits down to the femtomole level. The method and apparatus are valuable tools in the field of protein analysis and diagnostics.
    Type: Grant
    Filed: October 10, 2011
    Date of Patent: September 16, 2014
    Inventors: Fabio Polato, Mathias Rainer, Douglas T. Gjerde, Guenther Bonn
  • Publication number: 20140251918
    Abstract: An automated or semi-automated method was developed for the isolation of proteins using lanthanide metals. Phosphoproteins and glycoproteins can be isolated from complex biological samples using filtration with novel column configurations.
    Type: Application
    Filed: March 10, 2014
    Publication date: September 11, 2014
    Inventors: Matthias Rainer, Lee Hoang, Douglas T. Gjerde, Guenther Bonn
  • Publication number: 20140200330
    Abstract: The invention provides methods and apparatus for the selective isolation of phosphorylated and glycosylated proteins and their fragments. A lanthanide metal cation is used to precipitate proteins or protein fragments containing phospho groups and/or glyco groups. The sample preparation method can be used for many types of biological samples, including HeLa cells, food, and human cerebrospinal fluid. The proteins are isolated, recovered and ready for analysis by mass spectrometry or other analytical methods allowing detection limits down to the femtomole level. The method and apparatus are valuable tools in the field of protein analysis and diagnostics.
    Type: Application
    Filed: January 17, 2013
    Publication date: July 17, 2014
    Inventors: Matthias Rainer, Fabio Polato, Douglas T. Gjerde, Guenther Bonn
  • Patent number: 8753661
    Abstract: A base body contains a substrate that is at least partially coated with a carbon-containing layer. The carbon-containing layer is at least partially functionalized with a molecule that is bound directly or via at least one linker or functional group to the carbon-containing layer. The base body, which has a functionalized carbon-containing surface, is capable of influencing biological processes during a corresponding functionalization.
    Type: Grant
    Filed: December 7, 2005
    Date of Patent: June 17, 2014
    Assignee: Diacoating GmbH
    Inventors: Doris Steinmüller-Nethl, Detlef Steinmüller, Frank Rudolf Kloss, Robert Gassner, Günther Bonn, Christian Wolfgang Huck, Muhammed Najam-Ul-Haq, Matthias Rainer, Günther Stecher
  • Publication number: 20140147502
    Abstract: The present invention relates to an antibacterial agent and a hydrolysate made of at least one extract that has been produced by extraction using ethanol/water from dried plant material of: a) at least one of the plants selected from the group consisting of: Verbena officinalis L., Sambucus nigra L., Primula veris L., Primula elatior (L.) Hill, and Gentiana lutea L.; and a mixture thereof; or b) a mixture of: Verbena officinalis L., Sambucus nigra L., Primula veris L., Gentiana lutea L., and Rumicis herba; and subsequent removal of the ethanol/water extraction agent, wherein the hydrolysate can be obtained from the extract via hydrolytic treatment using a mineral acid. The hydrolyzates according to the invention show a pronounced antibacterial effect against germs relevant to the skin, ears, nose, and throat and respiratory systems.
    Type: Application
    Filed: January 31, 2014
    Publication date: May 29, 2014
    Applicant: Bionorica AG
    Inventors: Guenther Bonn, Guenther Stecher, Michael A. Popp, Robert Mayer
  • Patent number: 8734857
    Abstract: The present invention relates to an antibacterial agent and a hydrolysate made of at least one extract that has been produced by extraction using ethanol/water from dried plant material of: a) at least one of the plants selected from the group consisting of: Verbena officinalis L., Sambucus nigra L., Primula veris L., Primula elatior (L.) Hill, and Gentiana lutea L.; and a mixture thereof; or b) a mixture of: Verbena officinalis L., Sambucus nigra L., Primula veris L., Gentiana lutea L., and Rumicis herba; and subsequent removal of the ethanol/water extraction agent, wherein the hydrolysate can be obtained from the extract via hydrolytic treatment using a mineral acid. The hydrolyzates according to the invention show a pronounced antibacterial effect against germs relevant to the skin, ears, nose, and throat and respiratory systems.
    Type: Grant
    Filed: October 30, 2008
    Date of Patent: May 27, 2014
    Assignee: Bionorica SE
    Inventors: Guenther Bonn, Guenther Stecher, Michael A. Popp, Robert Mayer
  • Patent number: 8586641
    Abstract: The present invention relates to a monolithic organic copolymer prepared by copolymerization of at least one monomer of the group consisting of styrene, (C1-C3)alkylstyrene, (meth)acrylic acid and esters thereof with a crosslinker in the presence of a macroporogen and a microporogen, wherein a) the sum of said at least one monomer of the group and the crosslinker is 10-20%, preferably 10-15%, by volume of the reaction mixture, with the rest being essentially macroporogen and microporogen, and the degree of said copolymerization is at least 70%, preferably at least 90%, more preferably at least 99%, or b) the sum of said at least one monomer of the group and the crosslinker is 30-50%, preferably 35-45%, by volume of the reaction mixture, with the rest being essentially macroporogen and microporogen, and the degree of said copolymerization is in the range of 25-60%, preferably 35-50%.
    Type: Grant
    Filed: October 19, 2006
    Date of Patent: November 19, 2013
    Assignee: Leopold-Franzens-Universitat Innsbruck
    Inventors: Lukas Trojer, Günther Bonn
  • Publication number: 20120255894
    Abstract: Method for covalently attaching polymeric monoliths to polyether ether ketone (PEEK) surfaces The present invention provides a method of covalently attaching a polymeric monolith to the internal surface of polyether ether ketone (PEEK) tubing and column housings, comprising the steps of: (a) reducing the ketone group of the PEEK to a hydroxyl group to obtain a modified PEEK, (b) optionally reacting the hydroxyl group obtained in step (a) with a compound having an active vinyl group to form a modified PEEK selected from the group of acrylate modified PEEK, methacrylate modified PEEK, styrene modified PEEK and epoxy modified PEEK, and (c) reacting the modified PEEK obtained in step (a) or (b) with a polymer or polymerization mixture for forming the polymeric monolith. Hereby, the mechanical stability and solvent durability of larger diameter monolithic columns as well as their overall performance are improved.
    Type: Application
    Filed: December 20, 2010
    Publication date: October 11, 2012
    Applicant: UNIVERSITAET INNSBRUCK
    Inventors: Guenther Bonn, Samuel Clark Ligon
  • Publication number: 20120088906
    Abstract: The invention provides methods and apparatus for the selective isolation of phosphorylated and glycosylated proteins and their fragments. Metal cation is used to precipitate proteins or protein fragments containing phospho groups and/or glyco groups. The sample preparation method can be used for several types of biological samples, including HeLa cells, food, and human cerebrospinal fluid. The proteins are isolated, recovered and ready for analysis by mass spectrometry or other analytical methods allowing detection limits down to the femtomole level. The method and apparatus are valuable tools in the field of protein analysis and diagnostics.
    Type: Application
    Filed: October 10, 2011
    Publication date: April 12, 2012
    Inventors: Fabio Polato, Mathias Rainer, Douglas T. Gjerde, Guenther Bonn
  • Patent number: 8105513
    Abstract: The present invention relates to a pipette tip which is fitted with a porous organic monolith which is doped with active particles. Due to a unique polymerization method, the extraction tips stay highly permeable which allows sample to pass through the monolithic bed. The extraction tip represents an ideal tool for solid phase extraction, especially for desalting, isolating and purifying biomolecules such as peptides and proteins.
    Type: Grant
    Filed: June 5, 2009
    Date of Patent: January 31, 2012
    Inventors: Alexander Bonn, Guenther Bonn, Christian Huck, Bernhard Maerk, Harald Sonderegger, Mathias Rainer, Douglas T. Gjerde
  • Patent number: 8053247
    Abstract: The invention provides methods and apparatus for automated sample preparation for MALDI-TOF MS using columns in combination with a liquid handling system. The samples are typically biological such as serum or urine. The columns typically include a bed of media positioned within a modified pipette tip. In some embodiments, the invention provides methods for storing the prepared samples.
    Type: Grant
    Filed: October 10, 2007
    Date of Patent: November 8, 2011
    Assignee: PhyNexus, Inc.
    Inventors: Isabel Feuerstein, Günther Bonn, Douglas T. Gjerde, Christian Huck, Guenther Stecher
  • Publication number: 20100323013
    Abstract: The present invention relates to an antibacterial agent and a hydrolysate made of at least one extract that has been produced by extraction using ethanol/water from dried plant material of: a) at least one of the plants selected from the group consisting of: Verbena officinalis L., Sambucus nigra L., Primula veris L., Primula elatior (L.) Hill, and Gentiana lutea L.; and a mixture thereof; or b) a mixture of: Verbena officinalis L., Sambucus nigra L., Primula veris L., Gentiana lutea L., and Rumicis herba; and subsequent removal of the ethanol/water extraction agent, wherein the hydrolysate can be obtained from the extract via hydrolytic treatment using a mineral acid. The hydrolyzates according to the invention show a pronounced antibacterial effect against germs relevant to the skin, ears, nose, and throat and respiratory systems.
    Type: Application
    Filed: October 30, 2008
    Publication date: December 23, 2010
    Applicant: BIONORICA SE
    Inventors: Guenther Bonn, Guenther Stecher, Michael A. Popp, Robert Mayer
  • Patent number: 7715002
    Abstract: A method is provided for characterizing a scientific material, such as a silicate material, a polymer material and/or nanomaterial. The method can include the steps of irradiating a measuring light of a predetermined wavelength range into material specimens, recording the measuring light reflected and/or reemitted by the material specimens, determining a ratio depending on the wave lengths of irradiated to detected measuring light (spectrum), and numerical-mathematical processing of spectral data of single material specimens for determining the characteristic features of the material specimens.
    Type: Grant
    Filed: January 23, 2007
    Date of Patent: May 11, 2010
    Assignee: Bionorica AG
    Inventors: Michael A. Popp, Guenther Bonn, Christian W. Huck