Patents by Inventor Gugene Kang

Gugene Kang has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • GENERATION OF PRIMORDIAL GERM CELLS AND METHODS OF USING THE SAME
    Publication number: 20230242871
    Abstract: Provided herein are, inter alia, compositions and methods for generating a population of PGCs with improved efficiencies and line-to-line consistency. Inductive signals are temporally dynamic: WNT activation for 12 hours incipiently differentiates primed hPSCs into posterior epiblast, while subsequently, sharp WNT inhibition together with BMP activation specifies PGCs. hPSC-derived PGCs can be easily purified by virtue of their CXCR4+PDGFR?-GARP-surface-marker profile.
    Type: Application
    Filed: May 28, 2021
    Publication date: August 3, 2023
    Inventors: Vittorio Sebastiano, Kyle M. Loh, Gugene Kang