Patents by Inventor Gui-Dong Zhu

Gui-Dong Zhu has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Microstrip filter
    Patent number: 8248191
    Abstract: A filter includes a circuit board, a low-pass filter circuit, and a high-pass filter circuit. The circuit board includes at least one metal layer, and a dielectric layer attached on the at least one metal layer. The low-pass filter circuit is defined in the metal layer, and includes a main line that has two parallel portions, and a modulating circuit serving as a capacitor connected to the main line of the low-pass filter circuit. The high-pass filter circuit defined in the metal layer includes a main line that has two parallel portions and is connected to the low-pass filter circuit, and a modulating circuit serving as a conductor connected to the main line of the high-pass filter circuit.
    Type: Grant
    Filed: February 3, 2010
    Date of Patent: August 21, 2012
    Assignees: Hong Fu Jin Precision Industry (ShenZhen) Co., Ltd., Hon Hai Precision Industry Co., Ltd.
    Inventors: Guang-Ze Li, Gui-Dong Zhu
  • 2-substituted-1H-benzimidazole-4-carboxamides are PARP inhibitors
    Patent number: 8217070
    Abstract: Compounds of Formula (I) inhibit the PARP enzyme and are useful for treating a disease or a disorder associated with PARP. Also disclosed are pharmaceutical compositions comprising compounds of Formula (I), methods of treatment comprising compounds of Formula (I), and methods of inhibiting the PARP enzyme comprising compounds of Formula (I).
    Type: Grant
    Filed: April 22, 2010
    Date of Patent: July 10, 2012
    Assignee: Abbott Laboratories
    Inventors: Gui-Dong Zhu, Virajkumar B. Gandhi, Jianchun Gong, Thomas D. Penning, Vincent L. Giranda, Sheela Thomas
  • Poly(ADP-ribose)polymerase inhibitors
    Patent number: 8143284
    Abstract: Compounds which inhibit the activity of poly(ADP-ribose)polymerase, compositions containing the compounds and methods of treating diseases using the compounds is disclosed.
    Type: Grant
    Filed: October 4, 2007
    Date of Patent: March 27, 2012
    Assignee: Abbott Laboratories
    Inventors: Virajkumar B. Gandhi, Vincent Louis Giranda, Thomas D. Penning, Gui-Dong Zhu
  • BENZIMIDAZOLE POLY(ADP RIBOSE)POLYMERASE INHIBITORS
    Publication number: 20120046303
    Abstract: Compounds which inhibit the activity of poly(ADP-ribose)polymerase (PARP), compositions containing the compounds and methods of treating diseases using them are disclosed.
    Type: Application
    Filed: October 27, 2011
    Publication date: February 23, 2012
    Applicant: ABBOTT LABORATORIES
    Inventors: Virajkumar B. Gandhi, Vincent L. Giranda, Jianchun Gong, Thomas D. Penning, Gui-Dong Zhu
  • Benzimidazole poly(ADP ribose)polymerase inhibitors
    Patent number: 8067613
    Abstract: Compounds which inhibit the activity of poly(ADP-ribose)polymerase (PARP), compositions containing the compounds and methods of treating diseases using them are disclosed.
    Type: Grant
    Filed: July 15, 2008
    Date of Patent: November 29, 2011
    Assignee: Abbott Laboratories
    Inventors: Virajkumar B. Gandhi, Vincent L. Giranda, Jianchun Gong, Thomas D Penning, Gui-Dong Zhu
  • PHTHALAZIN-(2H)-ONE INHIBITORS OF KINASES
    Publication number: 20110257187
    Abstract: The present invention relates to compounds of formula (I) or pharmaceutical acceptable salts, wherein R1a, R1b, R1c, X, Y, Z, n, and m are defined in the description. The present invention relates also to compositions containing said compounds which are useful for inhibiting kinases such as Cdc7 and methods of treating diseases such as cancer.
    Type: Application
    Filed: April 14, 2011
    Publication date: October 20, 2011
    Applicant: ABBOTT LABORATORIES
    Inventors: Gui-Dong Zhu, Virajkumar B. Gandhi, Alexander R. Shoemaker, Thomas D. Penning, Jianchun Gong
  • PYRROLOPYRAZINONE INHIBITORS OF KINASES
    Publication number: 20110257189
    Abstract: The present invention relates to compounds of formula (I) or pharmaceutical acceptable salts, wherein R1a, R1b, R1c, X, Y, Z, n, and m are defined in the description. The present invention relates also to compositions containing said compounds which are useful for inhibiting kinases such as Cdc7 and methods of treating diseases such as cancer.
    Type: Application
    Filed: April 14, 2011
    Publication date: October 20, 2011
    Applicant: ABBOTT LABORATORIES
    Inventors: Gui-Dong Zhu, Virajkumar B. Gandhi, Alexander R. Shoemaker, Thomas D. Penning, Jianchun Gong
  • 2-{(R)-2-methylpyrrolidin-2-yl)-1H-benzimidazole-4-carboxamide crystalline form 2
    Patent number: 8013168
    Abstract: 2-((R)-2-Methylpyrrolidin-2-yl)-1H-benzimidazole-4-carboxamide Crystalline Form 2, ways to make it, compositions comprising it and made using it, and methods of treating patients having disease using it are disclosed.
    Type: Grant
    Filed: October 10, 2008
    Date of Patent: September 6, 2011
    Assignee: Abbott Laboratories
    Inventor: Gui-Dong Zhu
  • Substituted 1H-benzimidazole-4-carboxamides are potent PARP inhibitors
    Patent number: 7999117
    Abstract: The present invention relates to 1H-benzimidazole-4-carboxamides of formula (I), their preparation, and their use as inhibitors of the enzyme poly(ADP-ribose)polymerase for the preparation of drugs.
    Type: Grant
    Filed: March 30, 2009
    Date of Patent: August 16, 2011
    Inventors: Vincent L. Giranda, Thomas D. Penning, Virajkumar B. Gandhi, Sheela A. Thomas, Gui-Dong Zhu, Jianchun Gong
  • ENCRYPTED SIGNAL DETECTION CIRCUIT AND VIDEO DEVICE USING THE SAME
    Publication number: 20110194689
    Abstract: A video device includes a video signal generation circuit, an encrypted signal detection circuit and a central processing unit (CPU). The encrypted signal detection circuit detects encrypted messages in video signals output from the video signal generation circuit and outputs stable trigger control signals to the CPU, which includes an amplifier circuit, a separation circuit, a reverse circuit, a delay circuit and a trigger circuit. The video signals are amplified via the amplifier circuit and negative phase pulse signals are extracted from the video signals via the separation circuit. The reverse circuit converts the negative phase pulse signals to positive phase pulse signals that are delayed via the delay circuit. The trigger circuit outputs the stable trigger control signals based on the delayed positive phase pulse circuit.
    Type: Application
    Filed: April 14, 2010
    Publication date: August 11, 2011
    Applicants: HONG FU JIN PRECISION INDUSTRY (ShenZhen) CO., LTD ., HON HAI PRECISION INDUSTRY CO., LTD.
    Inventor: GUI-DONG ZHU
  • MICROSTRIP FILTER
    Publication number: 20110068883
    Abstract: A filter includes a circuit board, a low-pass filter circuit, and a high-pass filter circuit. The circuit board includes at least one metal layer, and a dielectric layer attached on the at least one metal layer. The low-pass filter circuit is defined in the metal layer, and includes a main line that has two parallel portions, and a modulating circuit serving as a capacitor connected to the main line of the low-pass filter circuit. The high-pass filter circuit defined in the metal layer includes a main line that has two parallel portions and is connected to the low-pass filter circuit, and a modulating circuit serving as a conductor connected to the main line of the high-pass filter circuit.
    Type: Application
    Filed: February 3, 2010
    Publication date: March 24, 2011
    Applicants: HONG FU JIN PRECISION INDUSTRY (ShenZhen) CO., LTD, HON HAI PRECISION INDUSTRY CO., LTD.
    Inventors: GUANG-ZE LI, GUI-DONG ZHU
  • PYRROLOPYRAZINE INHIBITORS OF KINASES
    Publication number: 20110015172
    Abstract: The present invention relates to compounds of formula (I) or pharmaceutical acceptable salts, wherein R1a, R1b, X, and Y are defined in the description. The present invention relates also to compositions containing said compounds which are useful for inhibiting kinases such as Cdc7 and methods of treating diseases such as cancer.
    Type: Application
    Filed: July 15, 2010
    Publication date: January 20, 2011
    Applicant: ABBOTT LABORATORIES
    Inventors: Thomas D. Penning, Virajkumar B. Gandhi, Gui-Dong Zhu, Yunsong Tong, Keith W. Woods, Chunqiu Lai, Jane Gong, Alan S. Florjancic
  • 2-SUBSTITUTED-1H-BENZIMIDAZOLE-4-CARBOXAMIDES ARE PARP INHIBITORS
    Publication number: 20100234425
    Abstract: Compounds of Formula (I) inhibit the PARP enzyme and are useful for treating a disease or a disorder associated with PARP. Also disclosed are pharmaceutical compositions comprising compounds of Formula (I), methods of treatment comprising compounds of Formula (I), and methods of inhibiting the PARP enzyme comprising compounds of Formula (I).
    Type: Application
    Filed: April 22, 2010
    Publication date: September 16, 2010
    Applicant: ABBOTT LABORATORIES
    Inventors: Gui-Dong Zhu, Virajkumar B. Gandhi, Jianchun Gong, Thomas D. Penning, Vincent L. Giranda, Sheela Thomas
  • 2-substituted-1 h-benzimidazile-4-carboxamides are PARP inhibitors
    Patent number: 7728026
    Abstract: Compounds of Formula (I) inhibit the PARP enzyme and are useful for treating a disease or a disorder associated with PARP. Also disclosed are pharmaceutical compositions comprising compounds of Formula (I), method of treatment comprising compounds of Formula (I), and methods of inhibiting the PARP enzyme comprising compound of Formula (I).
    Type: Grant
    Filed: April 11, 2006
    Date of Patent: June 1, 2010
    Assignee: Abbott Laboratories, Inc.
    Inventors: Gui-Dong Zhu, Virajkumar B. Gandhi, Jianchun Gong, Thomas D. Penning, Vincent L. Giranda, Sheela Thomas
  • Substituted 1H-benzimidazole-4-carboxamides are potent PARP inhibitors
    Patent number: 7595406
    Abstract: Compounds of Formula (I) inhibit the PARP enzyme and are useful for treating a disease or a disorder associated with PARP. Also disclosed are pharmaceutical compositions comprising compounds of Formula (I), methods of treatment comprising compounds of Formula (I), and methods of inhibiting the PARP enzyme comprising compounds of Formula (I).
    Type: Grant
    Filed: July 30, 2007
    Date of Patent: September 29, 2009
    Assignee: Abbott Laboratories Inc.
    Inventors: Thomas D. Penning, Sheela A. Thomas, Gui-Dong Zhu, Jianchun Gong, Vincent L. Giranda, Viraj B. Gandhi
  • SUBSTITUTED 1H-BENZIMIDAZOLE-4-CARBOXAMIDES ARE POTENT PARP INHIBITORS
    Publication number: 20090186877
    Abstract: The present invention relates to 1H-benzimidazole-4-carboxamides of formula (I), their preparation, and their use as inhibitors of the enzyme poly(ADP-ribose)polymerase for the preparation of drugs.
    Type: Application
    Filed: March 30, 2009
    Publication date: July 23, 2009
    Applicant: Abbott Laboratories
    Inventors: Vincent L. Giranda, Thomas D. Penning, Virajkumar B. Gandhi, Sheela A. Thomas, Gui-Dong Zhu, Jianchun Gong
  • 1H-benzimidazole-4-carboxamides substituted with a quaternary carbon at the 2-position are potent PARP inhibitors
    Patent number: 7550603
    Abstract: Compounds of Formula (I) inhibit the PARP enzyme and are useful for treating a disease or a disorder associated with PARP. Also disclosed are pharmaceutical compositions comprising compounds of Formula (I), methods of treatment comprising compounds of Formula (I), and methods of inhibiting the PARP enzyme comprising compounds of Formula (I).
    Type: Grant
    Filed: April 11, 2006
    Date of Patent: June 23, 2009
    Assignee: Abbott Laboratories Inc.
    Inventors: Gui-Dong Zhu, Jianchun Gong, Virajkumar B. Gandhi, Thomas D. Penning, Vincent L. Giranda
  • 2-{(R)-2-METHYLPYRROLIDIN-2-YL)-1H-BENZIMIDAZOLE-4-CARBOXAMIDE CRYSTALLINE FORM 2
    Publication number: 20090099246
    Abstract: 2-((R)-2-Methylpyrrolidin-2-yl)- I H-benzimidazole-4-carboxamide Crystalline Form 2, ways to make it, compositions comprising it and made using it, and methods of treating patients having disease using it are disclosed.
    Type: Application
    Filed: October 10, 2008
    Publication date: April 16, 2009
    Applicant: ABBOTT LABORATORIES
    Inventor: Gui-Dong Zhu
  • BENZIMIDAZOLE POLY(ADP RIBOSE)POLYMERASE INHIBITORS
    Publication number: 20090030016
    Abstract: Compounds which inhibit the activity of poly(ADP-ribose)polymerase (PARP), compositions containing the compounds and methods of treating diseases using them are disclosed.
    Type: Application
    Filed: July 15, 2008
    Publication date: January 29, 2009
    Applicant: ABBOTT LABORATORIES
    Inventors: Virajkumar B. Gandhi, Vincent L. Giranda, Jianchun Gong, Thomas D. Penning, Gui-Dong Zhu
  • Substituted 1H-benzimidazole-4-carboxamides are potent PARP inhibitors
    Patent number: 7462724
    Abstract: Compounds of Formula (I) inhibit the PARP enzyme and are useful for treating a disease or a disorder associated with PARP. Also disclosed are pharmaceutical compositions comprising compounds of Formula (I), methods of treatment comprising compounds of Formula (I), and methods of inhibiting the PARP enzyme comprising compounds of Formula (I).
    Type: Grant
    Filed: November 15, 2006
    Date of Patent: December 9, 2008
    Assignee: Abbott Laboratories
    Inventors: Thomas D. Penning, Sheela A. Thomas, Gui-Dong Zhu, Jianchun Gong, Vincent L. Giranda, Viraj B. Gandhi