Patents by Inventor Guido Furlotti

Guido Furlotti has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • 1H-indazole-3-carboxamide compounds as glycogen synthase kinase 3 beta inhibitors
    Patent number: 11472795
    Abstract: The present invention relates to the 1H-indazole-3-carboxamide compounds as glycogen synthase kinase 3 beta (GSK-3?) inhibitors and to their use in the treatment of GSK-3?-related disorders such as, for example, (i) insulin-resistance disorders; (ii) neurodegenerative diseases; (iii) mood disorders; (iv) schizophrenic disorders; (v) cancerous disorders; (vi) inflammation, (vii) osteoporosis, (viii) cardiac hypertrophy, (ix) epilepsies and (x) neuropathic pain.
    Type: Grant
    Filed: May 6, 2019
    Date of Patent: October 18, 2022
    Assignee: AZIENDE CHIMICHE RIUNITE ANGELINI FRANCESCO—A.C.R.A.F. S.p.A.
    Inventors: Guido Furlotti, Claudia Cavarischia, Rosa Buonfiglio, Rosella Ombrato, Tommaso Iacoangeli
  • 1H-INDAZOLE-3-CARBOXAMIDE COMPOUNDS AS GLYCOGEN SYNTHASE KINASE 3 BETA INHIBITORS
    Publication number: 20210053956
    Abstract: The present invention relates to the 1H-indazole-3-carboxamide compounds as glycogen synthase kinase 3 beta (GSK-3?) inhibitors and to their use in the treatment of GSK-3?-related disorders such as, for example, (i) insulin-resistance disorders; (ii) neurodegenerative diseases; (iii) mood disorders; (iv) schizophrenic disorders; (v) cancerous disorders; (vi) inflammation, (vii) osteoporosis, (viii) cardiac hypertrophy, (ix) epilepsies and (x) neuropathic pain.
    Type: Application
    Filed: May 6, 2019
    Publication date: February 25, 2021
    Applicant: AZIENDE CHIMICHE RIUNITE ANGLELINI FRANCESCO - A.C.R.A.F. S.p.A
    Inventors: Guido FURLOTTI, Claudia CAVARISCHIA, Rosa BUONFIGLIO, Rosella OMBRATO, Tommaso IACOANGELI
  • CONTINUOUS PROCESS FOR THE PREPARATION OF TRAZODONE
    Publication number: 20210032243
    Abstract: The present invention relates to an improved process for the preparation of trazodone. In particular, the present invention relates to a continuous process for the preparation of trazodone. More in particular, the present invention relates to a new method for the preparation of trazodone, said method comprising at least one step consisting of a continuous process performed in a flow reactor.
    Type: Application
    Filed: February 5, 2019
    Publication date: February 4, 2021
    Applicant: AZIENDE CHIMICHE RIUNITE ANGELINI FRANCESCO A.C.R.A.F. S.p.A.
    Inventors: Tommaso IACOANGELI, Leonardo Mario MORO, Giuliano CARACCIOLO TORCHIAROLO, Claudia CAVARISCHIA, Guido FURLOTTI
  • Antibacterial compounds
    Patent number: 10640488
    Abstract: The present invention relates to novel antibacterial compounds, pharmaceutical compositions containing them and their use as antimicrobials.
    Type: Grant
    Filed: June 5, 2017
    Date of Patent: May 5, 2020
    Assignee: AZIENDE CHIMICHE RIUNITE ANGELINI FRANCESCO A.C.R.A.F. S.p.A.
    Inventors: Rosella Ombrato, Gabriele Magaro', Barbara Garofalo, Guido Furlotti, Giorgina Mangano, Alessandra Capezzone de Joannon
  • Antibacterial compounds
    Patent number: 10633366
    Abstract: The present invention relates to novel antibacterial compounds (1) as defined below, pharmaceutical compositions containing them and their use as antimicrobials. A compound of formula (1): A-L1-Y-L2-R—B, wherein A is a cyclic group having one of the following formulae (I), (II) and (III), and wherein B is cyclic group having one of the following formulae (IV) to (IX).
    Type: Grant
    Filed: June 5, 2017
    Date of Patent: April 28, 2020
    Assignee: AZIENDE CHIMICHE RIUNITE ANGELINI FRANCESCO A.C.R.A.F. S.p.A.
    Inventors: Rosella Ombrato, Gabriele Magaro, Barbara Garofalo, Guido Furlotti, Giorgina Mangano, Alessandra Capezzone De Joannon
  • NEW ANTIBACTERIAL COMPOUNDS
    Publication number: 20200095225
    Abstract: The present invention relates to novel antibacterial compounds, pharmaceutical compositions containing them and their use as antimicrobials.
    Type: Application
    Filed: June 5, 2017
    Publication date: March 26, 2020
    Applicant: AZIENDE CHIMICHE RIUNITE ANGELINI FRANCESCO A.C.R.A.F. S.p.A.
    Inventors: Rosella OMBRATO, Gabriele MAGARO, Barbara GAROFALO, Guido FURLOTTI, Giorgina MANGANO, Alessandra CAPEZZONE DE JOANNON
  • NEW ANTIBACTERIAL COMPOUNDS
    Publication number: 20190256495
    Abstract: The present invention relates to novel antibacterial compounds, pharmaceutical compositions containing them and their use as antimicrobials.
    Type: Application
    Filed: June 5, 2017
    Publication date: August 22, 2019
    Applicant: AZIENDE CHIMICHE RIUNITE ANGELINI FRANCESCO A.C.R.A.F. S.p.A.
    Inventors: Rosella OMBRATO, Gabriele MAGARO, Barbara GAROFALO, Guido FURLOTTI, Giorgina MANGANO, Alessandra CAPEZZONE DE JOANNON
  • Antibacterial compounds
    Patent number: 10369130
    Abstract: The present invention relates to novel antibacterial compounds, pharmaceutical compositions containing them and their use as antimicrobials.
    Type: Grant
    Filed: December 11, 2015
    Date of Patent: August 6, 2019
    Assignee: AZIEN DE CHIMICHE RIUNITE ANGELINI FRANCESCO A.C.R.A.F. S.p.A.
    Inventors: Rosella Ombrato, Barbara Garofalo, Giorgina Mangano, Alessandra Capezzone De Joannon, Gaia Corso, Gabriele Magaro′, Guido Furlotti, Tommaso Iacoangeli
  • NEW ANTIBACTERIAL COMPOUNDS
    Publication number: 20190161472
    Abstract: The present invention relates to novel antibacterial compounds (1) as defined below, pharmaceutical compositions containing them and their use as antimicrobials. A compound of formula (1): A-L1-Y-L2-R-B, wherein A is a cyclic group having one of the following formulae (I), (II) and (III), and wherein B is cyclic group having one of the following formulae (IV) to (IX).
    Type: Application
    Filed: June 5, 2017
    Publication date: May 30, 2019
    Applicant: AZIENDE CHIMICHE RIUNITE ANGELINI FRANCESCO A.C.R.A.F. S.p.A.
    Inventors: Rosella OMBRATO, Gabriele MAGARO, Barbara GAROFALO, Guido FURLOTTI, Giorgina MANGANO, Alessandra CAPEZZONE DE JOANNON
  • Antibacterial compounds having broad spectrum of activity
    Patent number: 10221144
    Abstract: The present invention relates to novel antibacterial compounds, pharmaceutical compositions containing them and their use as antimicrobials.
    Type: Grant
    Filed: December 14, 2015
    Date of Patent: March 5, 2019
    Assignee: AZIENDE CHIMICHE RIUNITE ANGELINI FRANCESCO A.C.R.A.F. S.p.A.
    Inventors: Rosella Ombrato, Barbara Garofalo, Giorgina Mangano, Alessandra Capezzone De Joannon, Gaia Corso, Claudia Cavarischia, Guido Furlotti, Tommaso Iacoangeli
  • 1H-indazole-3-carboxamide compounds as glycogen synthase kinase 3 beta inhibitors
    Patent number: 10160746
    Abstract: The present invention relates to the 1H-indazole-3-carboxamide compounds as glycogen synthase kinase 3 beta (GSK-3?) inhibitors and to their use in the treatment of GSK-3?-related disorders such as, for example, (i) insulin-resistance disorders; (ii) neurodegenerative diseases; (iii) mood disorders; (iv) schizophrenic disorders; (v) cancerous disorders; (vi) inflammation, (vii) substance abuse disorders; (viii) epilepsies; and (ix) neuropathic pain.
    Type: Grant
    Filed: February 22, 2017
    Date of Patent: December 25, 2018
    Assignee: AZIENDE CHIMICHE RIUNITE ANGELINI FRANCESCO A.C.R.A.F. S.p.A.
    Inventors: Maria Alessandra Alisi, Nicola Cazzolla, Patrizia Dragone, Guido Furlotti, Caterina Maugeri, Rosella Ombrato, Francesca Mancini
  • 3-aminocarbazole compound, pharmaceutical composition containing it and preparation method therefor
    Patent number: 10005730
    Abstract: The present invention relates to novel benzoyl derivatives of 3-aminocarbazole, to a pharmaceutical composition containing them, to a method for preparing them and to the use of such compounds for the production of a drug that is useful in the treatment or prevention of disturbances associated with the production of prostaglandin E2 (PGE2), for instance inflammatory processes, pain, fever, tumours, Alzheimer's disease and atherosclerosis.
    Type: Grant
    Filed: December 15, 2015
    Date of Patent: June 26, 2018
    Assignee: AZIENDE CHIMICHE RIUNITE ANGELINI FRANCESCO A.C.R.A.F. S.p.A.
    Inventors: Maria Alessandra Alisi, Nicola Cazzolla, Isabella Coletta, Patrizia Dragone, Guido Furlotti, Barbara Garofalo, Angelo Guglielmotti, Giorgina Mangano, Caterina Maugeri
  • ANTIBACTERIAL COMPOUNDS HAVING BROAD SPECTRUM OF ACTIVITY
    Publication number: 20170369450
    Abstract: The present invention relates to novel antibacterial compounds, pharmaceutical compositions containing them and their use as antimicrobials.
    Type: Application
    Filed: December 14, 2015
    Publication date: December 28, 2017
    Applicant: AZIENDE CHIMICHE RIUNITE ANGELINI FRANCESCO A.C.R.A.F. S.p.A.
    Inventors: Rosella OMBRATO, Barbara GAROFALO, Giorgina MANGANO, Alessandra CAPEZZONE DE JOANNON, Gaia CORSO, Claudia CAVARISCHIA, Guido FURLOTTI, Tommaso IACOANGELI
  • ANTIBACTERIAL COMPOUNDS
    Publication number: 20170368017
    Abstract: The present invention relates to novel antibacterial compounds, pharmaceutical compositions containing them and their use as antimicrobials.
    Type: Application
    Filed: December 11, 2015
    Publication date: December 28, 2017
    Applicant: AZIENDE CHIMICHE RIUNITE ANGELINI FRANCESCO A.C.R.A.F. S.p.A.
    Inventors: Rosella OMBRATO, Barbara GAROFALO, Giorgina MANGANO, Alessandra CAPEZZONE DE JOANNON, Gaia CORSO, Gabriele MAGARO', Guido FURLOTTI, Tommaso IACOANGELI
  • Use of 1H-indazole-3-carboxamide compounds as glycogen synthase kinase 3 beta inhibitors
    Patent number: 9700551
    Abstract: The present invention relates to the new use of 1H-indazole-3-carboxamide compounds as glycogen synthase kinase 3 beta (GSK-3?) inhibitors and to their use in the treatment of GSK-3?-related disorders such as, for example, (i) insulin-resistance disorders; (ii) neurodegenerative diseases; (iii) mood disorders; (iv) schizophrenic disorders; (v) cancerous disorders; (vi) inflammation, (vii) substance abuse disorders; and (viii) epilepsies.
    Type: Grant
    Filed: August 13, 2015
    Date of Patent: July 11, 2017
    Assignee: AZIENDE CHIMICHE RIUNITE ANGELINI FRANCESCO A.C.R.A.F. S.P.A.
    Inventors: Maria Alessandra Alisi, Nicola Cazzolla, Barbara Garofalo, Guido Furlotti, Gabriele Magaro', Rosella Ombrato, Francesca Mancini
  • 1H-INDAZOLE-3-CARBOXAMIDE COMPOUNDS AS GLYCOGEN SYNTHASE KINASE 3 BETA INHIBITORS
    Publication number: 20170174657
    Abstract: The present invention relates to the 1H-indazole-3-carboxamide compounds as glycogen synthase kinase 3 beta (GSK-3?) inhibitors and to their use in the treatment of GSK-3?-related disorders such as, for example, (i) insulin-resistance disorders; (ii) neurodegenerative diseases; (iii) mood disorders; (iv) schizophrenic disorders; (v) cancerous disorders; (vi) inflammation, (vii) substance abuse disorders; (viii) epilepsies; and (ix) neuropathic pain.
    Type: Application
    Filed: March 7, 2017
    Publication date: June 22, 2017
    Applicant: AZIENDE CHIMICHE RIUNITE ANGELINI FRANCESCO A.C.R. A.F. S.P.A.
    Inventors: Maria Alessandra ALISI, Nicola CAZZOLLA, Patrizia DRAGONE, Guido FURLOTTI, Caterina MAUGERI, Rosella OMBRATO, Francesca MANCINI
  • 1H-INDAZOLE-3-CARBOXAMIDE COMPOUNDS AS GLYCOGEN SYNTHASE KINASE 3 BETA INHIBITORS
    Publication number: 20170157121
    Abstract: The present invention relates to the 1H-indazole-3-carboxamide compounds as glycogen synthase kinase 3 beta (GSK-3?) inhibitors and to their use in the treatment of GSK-3?-related disorders such as, for example, (i) insulin-resistance disorders; (ii) neurodegenerative diseases; (iii) mood disorders; (iv) schizophrenic disorders; (v) cancerous disorders; (vi) inflammation, (vii) substance abuse disorders; (viii) epilepsies; and (ix) neuropathic pain.
    Type: Application
    Filed: February 22, 2017
    Publication date: June 8, 2017
    Applicant: AZIENDE CHIMICHE RIUNITE ANGELINI FRANCESCO A.C.R.A.F. S.P.A.
    Inventors: Maria Alessandra ALISI, Nicola Cazzolla, Patrizia Dragone, Guido Furlotti, Caterina Maugeri, Rosella Ombrato, Francesca Mancini
  • Tricyclic indazole compound, method of preparation and pharmaceutical composition containing it
    Patent number: 9655906
    Abstract: Tricyclic indazole compound and its pharmaceutically acceptable salts of acid addition, use thereof, method and intermediates for preparing them, and a pharmaceutical composition containing them. The tricyclic indazole compound has the following general formula (I): in which R1, R2, L1, L2, X1, X2, X3, X4, X5, Y, W, m, and n have the meanings stated in the description.
    Type: Grant
    Filed: July 20, 2015
    Date of Patent: May 23, 2017
    Assignee: AZIENDE CHIMICHE RIUNITE ANGELINI FRANCESCO A.C.R.A.F. S.p.A.
    Inventors: Maria Alessandra Alisi, Nicola Cazzolla, Guido Furlotti, Beatrice Garrone, Gabriele Magaro, Giorgina Mangano
  • 1H-indazole-3-carboxamide compounds as glycogen synthase kinase 3 beta inhibitors
    Patent number: 9611249
    Abstract: The present invention relates to the 1H-indazole-3-carboxamide compounds having the following general formula (I) as glycogen synthase kinase 3 beta (GSK-3?) inhibitors and to their use in the treatment of GSK-3p-related disorders such as, for example, (i) insulin-resistance disorders; (ii) neurodegenerative diseases; (iii) mood disorders; (iv) schizophrenic disorders; (v) cancerous disorders; (vi) inflammation, (vii) substance abuse disorders; (viii) epilepsies; and (ix) neuropathic pain.
    Type: Grant
    Filed: February 7, 2013
    Date of Patent: April 4, 2017
    Assignee: AZIENDE CHIMICHE RIUNITE ANGELINI FRANCESCO A.C.R.A.F. S.P.A.
    Inventors: Maria Alessandra Alisi, Nicola Cazzolla, Patrizia Dragone, Guido Furlotti, Caterina Maugeri, Rosella Ombrato, Francesca Mancini
  • 3-AMINOCARBAZOLE COMPOUND, PHARMACEUTICAL COMPOSITION CONTAINING IT AND PREPARATION METHOD THEREFOR
    Publication number: 20160102056
    Abstract: The present invention relates to novel benzoyl derivatives of 3-aminocarbazole, to a pharmaceutical composition containing them, to a method for preparing them and to the use of such compounds for the production of a drug that is useful in the treatment or prevention of disturbances associated with the production of prostaglandin E2 (PGE2), for instance inflammatory processes, pain, fever, tumours, Alzheimer's disease and atherosclerosis.
    Type: Application
    Filed: December 15, 2015
    Publication date: April 14, 2016
    Applicant: AZIENDE CHIMICHE RIUNITE ANGELINI FRANCESCO A.C.R.A.F. S.p.A.
    Inventors: Maria Alessandra Alisi, Nicola Cazzolla, Isabella Coletta, Patrizia Dragone, Guido Furlotti, Barbara Garofalo, Angelo Guglielmotti, Giorgina Mangano, Caterina Maugeri