Patents by Inventor Guido JUNGE

Guido JUNGE has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • SOLUBILIZED APYRASES, METHODS AND USE
    Publication number: 20250179447
    Abstract: The invention relates to design and therapeutic use of solubilized apyrase polypeptides, pharmaceuticals compositions, therapeutic uses and methods useful for preventing and treating tissue damage.
    Type: Application
    Filed: September 26, 2024
    Publication date: June 5, 2025
    Inventors: Agostino CIRILLO, Hilmar EBERSBACH, Boerje HARALDSSON, Thomas HUBER, Guido JUNGE, Regina LINK, Max WARNCKE, Chao ZOU
  • Methods For Prevention Of Graft Rejection In Xenotransplantation
    Publication number: 20250136706
    Abstract: The present invention relates to methods, treatment regimens, uses, kits and therapies for prevention of graft rejection in solid organ transplantation, particularly solid organ xenotransplantation, by administering an anti-CD40 antibody or a combination of an anti-CD40 antibody and an anti-C5 antibody.
    Type: Application
    Filed: October 2, 2024
    Publication date: May 1, 2025
    Applicants: Novartis AG, Emory University, The UAB Research Foundation
    Inventors: Guido JUNGE, James RUSH, Andrew B. ADAMS, Alfred Joseph TECTOR, III
  • DEGRADATION OF EXTRACELLULAR TARGETS
    Publication number: 20240309084
    Abstract: The present disclosure features bifunctional compounds for the degradation of extracellular targets, as well as compositions and related methods thereof.
    Type: Application
    Filed: January 18, 2022
    Publication date: September 19, 2024
    Inventors: Martin ALLAN, Jeffrey BAGDANOFF, David Weninger BARNES, John BLANKENSHIP, James BRADNER, Kevin CLAIRMONT, Brian GRANDA, Guido JUNGE, Thomas SMITH, Elisabetta TRAGGIAI, Max WARNCKE
  • METHOD OF TREATING AN AUTOIMMUNE HEMATOLOGICAL DISORDER
    Publication number: 20240277689
    Abstract: Described herein are methods of treating an autoimmune benign hematological disorder (e.g., ITP, CAD, wAIHA, and TTP) with the Factor B inhibitor LNP023 (iptacopan) or a pharmaceutically acceptable salt thereof, e.g. iptacopan hydrochloride.
    Type: Application
    Filed: June 17, 2022
    Publication date: August 22, 2024
    Inventors: Raghav CHAWLA, Thomas HOLBRO, Guido JUNGE, Anna Svenja SCHUBART WELLENSIEK
  • Methods For Prevention Of Graft Rejection In Xenotransplantation
    Publication number: 20230203176
    Abstract: The present invention relates to methods, treatment regimens, uses, kits and therapies for prevention of graft rejection in solid organ transplantation, particularly solid organ xenotransplantation, by administering an anti-CD40 antibody or a combination of an anti-CD40 antibody and an anti-C5 antibody.
    Type: Application
    Filed: September 16, 2022
    Publication date: June 29, 2023
    Inventors: Guido JUNGE, James RUSH, Andrew B. ADAMS, Alfred Joseph TECTOR, III
  • SOLUBILIZED APYRASES, METHODS AND USE
    Publication number: 20220356455
    Abstract: The invention relates to design and therapeutic use of solubilized apyrase polypeptides, pharmaceuticals compositions, therapeutic uses and methods useful for preventing and treating tissue damage.
    Type: Application
    Filed: July 17, 2019
    Publication date: November 10, 2022
    Inventors: Agostino CIRILLO, Hilmar EBERSBACH, Boerje HARALDSSON, Thomas HUBER, Guido JUNGE, Regina LINK, Max WARNCKE, Chao ZOU
  • Bispecific Antibodies for use in treatment of NLRC4-GOF inflammasomapathy
    Publication number: 20220177569
    Abstract: The invention relates to bivalent bispecific monoclonal antibodies (bbmAb) or variants thereof for use in the treatment or for use in alleviating the symptoms of an NLRC4 inflammasomopathy, such as an NLRC4-GOF inflammasomopathy in a subject in need thereof. This invention also relates to bivalent bispecific monoclonal antibodies (bbmAb) or variants thereof for use in the treatment or for use in alleviating the symptoms of AIFEC in a subject in need thereof.
    Type: Application
    Filed: November 16, 2021
    Publication date: June 9, 2022
    Inventors: Guido JUNGE, Michael KIFFE, Jiri KOVARIK, Richard STEIN, Frank WALDRON-LYNCH