Abstract: An actuator (1) having an energy accumulator (6), with which an emergency drive (5) can be supplied, is configured to be tensioned by an electric motor (2). The motor (2) displaces at least one engaging element (41, 42) of the energy accumulator (6), on which a restoring force of the energy accumulator (6) acts, along an actuating travel in normal operating mode.

Abstract: The present invention relates to compounds of formula (I) or formula (II) or pharmaceutically acceptable salt, solvate or hydrate thereof, wherein said compound of formula (I) and said compound of formula II each comprises at least one ONO2 or ONO moiety; R1 is C1-C3alkyl; R2 is H, C1-C6alkyl, C3-C6cycloalkyl, C1-C2alkoxy, C2-C4alkenyl; R3 is C1-C4alkyl optionally substituted with C1-C2alkoxy, C3-C4cycloalkyl, C2-C4alkenyl; R4 and R5 are each independently H or C1-C6alkyl optionally substituted with F, OH, ONO, ONO2, COOH, C1-C3alkoxy, C3-C6cycloalkyl; or together with the nitrogen atom to which they are attached form a heterocyclic ring, wherein preferably said heterocyclic ring is selected from aziridine, azetidine, pyrollidine, piperidine, morpholine, piperazine, homo-piperazine, 2,5-diazabicyclo[2,2,1]heptane and 3,7-diazabicyclo[3,3,0]octane, wherein said heterocyclic ring is optionally substituted with independently one or more R6; R6 is C1-C6alkyl optionally substituted with independently one or more h

Abstract: An apparatus is disclosed. The apparatus includes an operating table column head assembly, a patient support surface assembly that is movable relative to the operating table column head assembly, and an actuating cylinder configured to move the patient support surface assembly relative to the operating table column head assembly, the actuating cylinder including a piston rod. A first gear rack is attached to the operating table column head assembly and a second gear rack is attached to the patient support surface assembly. A gear assembly is disposed on the piston rod of the actuating cylinder. The gear assembly engages with the first gear rack and the second gear rack. The first gear rack and the second gear rack move in substantially opposite directions relative to the gear assembly, when the actuating cylinder is actuated.

Abstract: Rotation unit (16) for connecting to an operating table for rotation of a patient's leg about its longitudinal axis, wherein the rotation unit (16) comprises: an interface (24) for attachment of the foot of the patient's leg on the rotation unit (16); a rotor, to which the interface (24) is connected in a torsionally resistant manner and which is used for rotation of the interface (24) and thus of the patient's leg about the longitudinal axis; a stator (42), on which the rotor is rotatably mounted, such that the rotor can rotate relative to the stator; a rotary handle (22) for rotation of the rotor; and a locking assembly (26) for blocking the rotation of the rotor relative to the stator. The locking assembly (26) can be actuated by means of an action on the rotary handle.

Abstract: A self-locking spindle traction mechanism for use in surgical procedures has a longitudinal axis (L). The mechanism may include an operating end, a connecting end for connecting a surgical accessory, and a threaded spindle drive. The spindle drive may include a spindle having an external thread, and a spindle nut that is seated on the spindle and has an internal thread. The mechanism may include a slide that is movable along the longitudinal axis by a relative rotation between the spindle and the spindle nut, a drive device that is situated on the operating end for rotationally driving the threaded spindle drive, and a gear. The gear may be connected between the drive device and the threaded spindle drive, so that the gear is configured for stepping up the speed of a rotational movement of the drive device and delivering it to the threaded spindle drive.

Abstract: This invention pertains generally to compounds of Formula (A), as further described herein, which act as beta-lactamase inhibitors, and salts, crystalline forms and formulations thereof. In certain aspects, the invention pertains to methods of using such compounds in combination with a beta-lactam antibiotic to treat infections caused by Gram-negative bacteria, including drug-resistant strains.

Abstract: A medical support arm may include a holding end, a coupling end, a coupling-end pivot joint for swiveling the support arm about a pivot axis (A1) and tilting the support arm about a tilt axis (A2), and a clamping mechanism with which the pivot joint can be locked or released as desired. The pivot joint allows the support arm to rotate exclusively about the tilt axis (A2) and the pivot axis (A1). A tilting device may have a tilting element and a cylindrical sliding surface on which the tilting element is seated. A pivot mechanism can have a guide ring and at least one ring guide surface that receives the guide ring. A tilting element, as part of the clamping mechanism, may be provided as a gripper clamp that secures both the tilting device and the pivot mechanism against rotation by clamping the central body.

Abstract: An operating table clamp is disclosed. The operating table clamp has a base body, a clamp assembly disposed on the base body, the clamp assembly having at least one bearing member configured to bear against the operating table member, and an activating member that is connected to the clamp assembly, the clamp assembly being brought by the activating member into a locked state in which the bearing member of the clamp assembly bears against the operating table member. In the locked state of the clamp assembly, the bearing member engages with an edge region of the operating table member, the edge region including an edge that is disposed between a first operating table member surface and a second operating table member surface, the first and second operating table member surfaces being angled relative to each other.

Abstract: The invention relates to an operating table column (10) for an operating table (100), said operating table column comprising a basic body (12) and a column head (14) to which a patient support (103) may be connected. Further, the operating table column (10) comprises a first linear actuator (20) and a second linear actuator (22) which are independently adjustable for changing the position of the column head (14) relative to the basic body (12). The first linear actuator (20) and the second linear actuator (22) each are oriented and arranged so as to perform an actuating motion in vertical direction when activated. The first linear actuator (20) is mechanically connected to the column head (14) via a first connecting area (30), and the second linear actuator (22) is mechanically connected to the column head (14) via a second connecting area (32).

Abstract: This invention pertains generally to compounds of Formula (A), as further described herein, which act as beta-lactamase inhibitors, and salts, crystalline forms and formulations thereof. In certain aspects, the invention pertains to methods of using such compounds in combination with a beta-lactam antibiotic to treat infections caused by Gram-negative bacteria, including drug-resistant strains.

Abstract: A device for height adjustment of an operating table, including a lifting carriage which is movable relative to a chassis of the operating table, including a primary guide having a first longitudinal axis about which the lifting carriage is rotatable, including a secondary guide having a second longitudinal axis, and including a guide means which is connected to the chassis of the operating table and which has a contact area in which the guide means contacts the secondary guide in a contact area of the secondary guide.

Abstract: This invention pertains generally to compounds of Formula (A), as further described herein, which act as beta-lactamase inhibitors, and salts, crystalline forms and formulations thereof. In certain aspects, the invention pertains to methods of using such compounds in combination with a beta-lactam antibiotic to treat infections caused by Gram-negative bacteria, including drug-resistant strains.

Abstract: An operating table base for an operating table is disclosed. The operating table base comprises at least two transport rollers that are moveable between a retracted position, in the base, and an extracted position, extending from the base. The operating table rests on at least one support element of the operating table when the rollers are in the retracted position. The operating table is movable on the transport rollers when the rollers are in the extracted position. The operating table base includes a first mechanical adjusting unit for moving the first transport roller between the retracted position and the extracted position and a second mechanical adjusting unit for moving the second transport roller between the retracted position and the extracted position. Both the first and the second adjusting units are actuatable by a first drive unit which is connected to the first and the second adjusting units via a mechanical connecting means.

Abstract: This invention pertains generally to compounds of Formula (A), as further described herein, which act as beta-lactamase inhibitors, and salts, crystalline forms and formulations thereof. In certain aspects, the invention pertains to methods of using such compounds in combination with a beta-lactam antibiotic to treat infections caused by Gram-negative bacteria, including drug-resistant strains.

Abstract: An apparatus is disclosed. The apparatus includes an operating table column head assembly, a patient support surface assembly that is movable relative to the operating table column head assembly, and an actuating cylinder configured to move the patient support surface assembly relative to the operating table column head assembly, the actuating cylinder including a piston rod. A first gear rack is attached to the operating table column head assembly and a second gear rack is attached to the patient support surface assembly. A gear assembly is disposed on the piston rod of the actuating cylinder. The gear assembly engages with the first gear rack and the second gear rack. The first gear rack and the second gear rack move in substantially opposite directions relative to the gear assembly, when the actuating cylinder is actuated.

Abstract: An extension device includes a patient support surface and an extension beam (16) that can be connected via an interface (14) to the patient support surface and that has a holder for a feed rod arrangement. The patient support surface has at least two longitudinal beams (10) parallel to each other that carry a pelvic support plate. The interface (14) includes a coupling part (36) on the support surface side and a coupling part (38) on the beam side rigidly connected to the extension beam (16). The coupling part (36) on the support surface side on one of the longitudinal beams (10) is supported such that it can pivot about an axis perpendicular to the pelvic support plate, and whereby the coupling part (36) on the support surface side can be locked by a locking device, which may be actuated by remote actuation, against a rotation about its pivot axis relative to the longitudinal beam (10).

Abstract: An operating table clamp is disclosed. The operating table clamp has a base body, a clamp assembly disposed on the base body, the clamp assembly having at least one bearing member configured to bear against the operating table member, and an activating member that is connected to the clamp assembly, the clamp assembly being brought by the activating member into a locked state in which the bearing member of the clamp assembly bears against the operating table member. In the locked state of the clamp assembly, the bearing member engages with an edge region of the operating table member, the edge region including an edge that is disposed between a first operating table member surface and a second operating table member surface, the first and second operating table member surfaces being angled relative to each other.

Abstract: The present invention describes new pyrrolo pyrimidine derivatives and pharmaceutically acceptable salts thereof which appear to interact with Bruton's tyrosine kinase (Btk). Accordingly, the novel pyrrolo pyrimidines may be effective in the treatment of autoimmune disorders, inflammatory diseases, allergic diseases, airway diseases, such as asthma and chronic obstructive pulmonary disease (COPD), transplant rejection, cancers e.g. of hematopoietic origin or solid tumors.

Abstract: The invention relates to an operating table column (10) for an operating table (100), said operating table column comprising a basic body (12) and a column head (14) to which a patient support (103) may be connected. Further, the operating table column (10) comprises a first linear actuator (20) and a second linear actuator (22) which are independently adjustable for changing the position of the column head (14) relative to the basic body (12). The first linear actuator (20) and the second linear actuator (22) each are oriented and arranged so as to perform an actuating motion in vertical direction when activated. The first linear actuator (20) is mechanically connected to the column head (14) via a first connecting area (30), and the second linear actuator (22) is mechanically connected to the column head (14) via a second connecting area (32).

Abstract: A device for height adjustment of an operating table (10), including a lifting carriage (40) which is movable relative to a chassis (38) of the operating table (10), including a primary guide (32, 33) having a first longitudinal axis (L1) about which the lifting carriage (40) is rotatable, including a secondary guide (34a) having a second longitudinal axis (L2), and including a guide means (36) which is connected to the chassis (38) of the operating table (10) and which has a contact area in which the guide means (36) contacts the secondary guide (34a) in a contact area of the secondary guide (34a).