Patents by Inventor Guido Melzer

Guido Melzer has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Adhesion receptor antagonists
    Patent number: 5532255
    Abstract: Compounds of the formula ##STR1## in which R.sup.1, X and Y have the meanings defined herein, and their salts, inhibit the binding of fibrinogen to the fibrinogen receptor and can be used for treating thrombosis, stroke, cardiac infarction, inflammations, arteriosclerosis, osteoporosis and tumors.
    Type: Grant
    Filed: April 29, 1994
    Date of Patent: July 2, 1996
    Assignee: Merck Patent Gesellschaft mit beschrankter Haftung
    Inventors: Peter Raddatz, Joachim Gante, Horst Juraczyk, Hanns Wurziger, Helmut Prucher, Sabine Bernotat-Danielowski, Guido Melzer
  • Lipid lowering and anti-thrombotic 6-arylpyridazin-3-ones and a process for their preparation
    Patent number: 4289774
    Abstract: Compounds of the formula ##STR1## wherein R.sup.1 is 4-biphenylyl, 4-phenoxyphenyl or 4-biphenylyl or 4-phenoxyphenyl substituted in the 4'-position by F, Cl, Br or I; R.sup.2 is H, C.sub.1-4 -alkyl, hydroxy-C.sub.1-4 -alkyl or pyridyl; R.sup.3 and R.sup.6 are each H or alkyl of 1-4 carbon atoms, or together are--(CH.sub.2).sub.4 --; and R.sup.4 and R.sup.5 are each H or together are a C--C bond; at least one of the radicals R.sup.2, R.sup.3 and R.sup.6 being other than hydrogen, possess valuable pharmacological properties, e.g., lower lipid levels and are anti-thrombotic.
    Type: Grant
    Filed: October 19, 1979
    Date of Patent: September 15, 1981
    Assignee: Merck Patent Gesellschaft mit beschrankter Haftung
    Inventors: Erich Schacht, Hans-Adolf Kurmeier, Joachim Gante, Reinhard Lissner, Guido Melzer, Dieter Orth