Patents by Inventor Guido Tricot

Guido Tricot has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • COMPOSITIONS AND METHODS FOR CANCER THERAPY
    Publication number: 20220160679
    Abstract: The invention provides compositions and methods to treat relapsed multiple myeloma with pharmacological ascorbic acid or a pharmaceutically acceptable salt thereof, and one or more anti-cancer therapies.
    Type: Application
    Filed: December 6, 2021
    Publication date: May 26, 2022
    Applicant: UNIVERSITY OF IOWA RESEARCH FOUNDATION
    Inventors: Fenghuang Zhan, Ivana Frech, Guido Tricot
  • Compositions and methods for cancer therapy
    Patent number: 11298338
    Abstract: The invention provides compositions and methods to treat a hyperproliferative disorder with ascorbate or a pharmaceutically acceptable salt thereof, and one or more anti-cancer therapies.
    Type: Grant
    Filed: June 6, 2017
    Date of Patent: April 12, 2022
    Assignee: UNIVERSITY OF IOWA RESEARCH FOUNDATION
    Inventors: Fenghuang Zhan, Ivana Frech, Guido Tricot
  • METHODS FOR IDENTIFYING MYELOMA TUMOR-INITIATING CELLS AND TARGETED THERAPY
    Publication number: 20200209247
    Abstract: In certain embodiments, the present invention provides a method of treating cancer in a patient comprising administering an effective amount of a therapeutic agent to the patient, wherein the cancer was determined to contain cells comprising cell marker CD24+. In certain embodiments, the cancer cells also comprise cell markers CD38+ and/or CD45?.
    Type: Application
    Filed: September 17, 2018
    Publication date: July 2, 2020
    Applicant: UNIVERSITY OF IOWA RESEARCH FOUNDATION
    Inventors: Ivana Frech, Fenghuang Zhan, Guido Tricot
  • COMPOSITIONS AND METHODS FOR CANCER THERAPY
    Publication number: 20190216771
    Abstract: The invention provides compositions and methods to treat a hyperproliferative disorder with ascorbate or a pharmaceutically acceptable salt thereof, and one or more anti-cancer therapies.
    Type: Application
    Filed: June 6, 2017
    Publication date: July 18, 2019
    Applicant: University Of Iowa Research Foundation
    Inventors: Fenghuang ZHAN, Ivana FRECH, Guido TRICOT
  • MULTIPLE MYELOMA PROGNOSIS AND TREATMENT
    Publication number: 20120184494
    Abstract: Disclosed herein are diagnostic and prognostic methods for determining the overall survival, and therapeutic regimes, for multiple myeloma patients. The methods involve the detection of PTHR1 gene expression alone or in combination with other clinical factors. The tests are suitable for diagnosing and monitoring treatment of patients having or suspected of having multiple myeloma. The disclosure also relates to proteasome inhibitors and other activators of PTHR1, for the treatment of multiple myeloma.
    Type: Application
    Filed: November 10, 2011
    Publication date: July 19, 2012
    Inventors: Maurizio Zangari, Fenghuang Zhan, Guido Tricot
  • MATERIALS AND METHODS FOR THE IDENTIFICATION OF DRUG-RESISTANT CANCERS AND TREATMENT OF SAME
    Publication number: 20120178089
    Abstract: Disclosed herein are diagnostic methods for identifying cancer and predicting drug resistance. The assays involve the detection of NEK2 gene expression alone or in combination with other genes or clinical factors. The test is suitable for diagnosing and monitoring treatment of subjects having or suspected of having a neoplastic disease, such as multiple myeloma. The disclosure also relates to inhibitors of NEK2 for the treatment of cancer, including drug-resistant multiple myeloma.
    Type: Application
    Filed: December 22, 2011
    Publication date: July 12, 2012
    Inventors: Fenghuang Zhan, Maurizio Zangari, Guido Tricot