Patents by Inventor Guido Trione

Guido Trione has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Procedure for the production of tiacumicin B
    Patent number: 9970041
    Abstract: The present invention relates to a procedure for the production of tiacumicin B comprising fermentation of a micro-organism capable of producing tiacumicin B, in particular of the species Dactylosporangium aurantiacum or Actinoplanes deccanensis, in a culture broth containing emulsifiers, such as ethoxylated castor oil, in combination with antifoaming products and vegetable oils.
    Type: Grant
    Filed: July 30, 2013
    Date of Patent: May 15, 2018
    Assignee: OLON S.P.A.
    Inventors: Guido Trione, Antonella Malcangi
  • Procedure For The Production Of Tiacumicin B
    Publication number: 20150203889
    Abstract: The present invention relates to a procedure for the production of tiacumicin B comprising fermentation of a micro-organism capable of producing tiacumicin B, in particular of the species Dactylosporangium aurantiacum or Actinoplanes deccanensis, in a culture broth containing emulsifiers, such as ethoxylated castor oil, in combination with antifoaming products and vegetable oils.
    Type: Application
    Filed: July 30, 2013
    Publication date: July 23, 2015
    Applicant: OLON S.P.A.
    Inventors: Guido Trione, Antonella Malcangi
  • PROCEDURE FOR THE PRODUCTION OF TIACUMICIN B
    Publication number: 20130266986
    Abstract: The present invention relates to a process for the production of tiacumicin B which comprises fermentation of a micro-organism of the species Dactylosporangium aurantiacum in a culture broth containing polysaccharides such as cellulose and derivatives thereof.
    Type: Application
    Filed: April 3, 2013
    Publication date: October 10, 2013
    Applicant: OLON S.p.A.
    Inventors: Antonella Malcangi, Guido Trione
  • Process for the production of daptomycin
    Patent number: 8313922
    Abstract: The present invention relates to an improved process for the production of Daptomycin by fermentation with Streptomyces roseosporus, in the presence of n-decanal or Cuphea oil as sources of the n-decanoyl side chain. These reagents allow to reduce toxicity effects on the bacteria and to avoid the use of solvents in the feeding solution.
    Type: Grant
    Filed: July 30, 2009
    Date of Patent: November 20, 2012
    Assignee: Antibioticos S.p.A.
    Inventors: Gianluca Bertetti, Antonella Malcangi, Roberto Muraca, Guido Trione, Alessia Rossi
  • PROCESS FOR THE PRODUCTION OF DAPTOMYCIN
    Publication number: 20100047873
    Abstract: The present invention relates to an improved process for the production of Daptomycin by fermentation with Streptomyces roseosporus, in the presence of n-decanal or Cuphea oil as sources of the n-decanoyl side chain. These reagents allow to reduce toxicity effects on the bacteria and to avoid the use of solvents in the feeding solution.
    Type: Application
    Filed: July 30, 2009
    Publication date: February 25, 2010
    Applicant: ANTIBIOTICOS S.p.A
    Inventors: Gianluca BERTETTI, Antonella Malcangi, Roberto Muraca, Guido Trione, Alessia Rossi