Patents by Inventor Guido Van Den Broeck

Guido Van Den Broeck has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Chimaeric gene coding for a transit peptide and a heterologous polypeptide
    Patent number: 5728925
    Abstract: Chimaeric DNA sequence which encodes: 1) a transit peptide of a cytoplasmic precursor of a chloroplast protein or polypeptide of a plant and 2) a protein or polypeptide that is heterologous to the transit peptide. The chimaeric DNA sequence can be used as a vector for transforming a plant cell so that a chimaeric precursor of the heterologous protein or polypeptide is produced in the cytoplasm of the cell and the chimaeric precursor then transports the heterologous protein or polypeptide in vivo into a chloroplast of the cell.
    Type: Grant
    Filed: April 28, 1995
    Date of Patent: March 17, 1998
    Assignees: Plant Genetic Systems, N.V., Bayer A.G.
    Inventors: Luis Herrera-Estrella, Guido Van Den Broeck, Marc Van Montagu, Peter Schreier, Jeff Schell, Hans J. Bohnert, Anthony R. Cashmore, Michael P. Timko, Albert P. Kausch
  • Chimaeric gene coding for a transit peptide and a heterologous peptide
    Patent number: 5717084
    Abstract: A chimaeric DNA sequence comprising:a) a nucleic acid sequence coding for a chimaeric protein or polypeptide comprising in sequence:1) a transit peptide of a cytoplasmatic precursor of a chloroplast protein or polypeptide of a plant species, and,2) a protein or polypeptide of interest which is different from a mature chloroplast protein or polypeptide contained in a natural cytoplasmatic precursor thereof, and,b) a promoter upstream of the nucleic acid sequence recognized by polymerases endogenous to a plant, whereby the chimaeric DNA sequence can be expressed in cells of the plant under the control of the promoter and the protein or polypeptide of interest can be translocated in the chloroplasts of the cells of the plant.
    Type: Grant
    Filed: June 6, 1995
    Date of Patent: February 10, 1998
    Assignees: Plant Genetic Systems, N.V., Bayer A.G.
    Inventors: Luis Herrera-Estrella, Guido Van Den Broeck, Marc Van Montagu, Peter Schreier, Jeff Schell, Hans J. Bohnert, Anthony R. Cash more, Michael P. Timko, Albert P. Kausch