Abstract: A control method and a control system based on a mobile robot are provided, which correspondingly obtain first feature information and second feature information according to a specific target object and a face region of the user present in region environment, and a delivery request message is sent to the mobile robot; the obstacle presence information is obtained during moving process of mobile robot along the moving path so as to adjust moving state of mobile robot; the corresponding third feature information is obtained according to the image of current region of mobile robot; whether the mobile robot performs an article unloading operation is controlled according to a comparison result between the third feature information and the second feature information; the efficient transportation paths are chose according to the moving path of the mobile robot, and the real-time situation of the destinations may be verified.