Patents by Inventor Guifen Zhang

Guifen Zhang has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20070015760
    Abstract: The invention relates to 2,4-dichloropyrrolo[1,2-f][1,2,4]triazines, which are intermediates useful in preparing at least one 2,4-disubstituted pyrrolotriazine compound, and at least one method for making such intermediates.
    Type: Application
    Filed: June 27, 2006
    Publication date: January 18, 2007
    Inventors: Harold Mastalerz, Guifen Zhang
  • Publication number: 20070004734
    Abstract: Described herein is at least one pyrrolo[1,2-f][1,2,4]triazine-2,4(1H,3H)-dione, which is an intermediates useful in preparing 2,4-disubstituted pyrrolotriazine compounds, and at least one method for making such intermediate.
    Type: Application
    Filed: June 27, 2006
    Publication date: January 4, 2007
    Inventors: Harold Mastalerz, Guifen Zhang
  • Patent number: 7102003
    Abstract: The present invention provides compounds of formula I and pharmaceutically acceptable salts thereof. The compounds of the invention inhibit tyrosine kinase activity of growth factor receptors such as HER1, HER2 and HER4 thereby making them useful as antiproliferative agents. The compounds are also useful for the treatment of other diseases associated with signal transduction pathways operating through growth factor receptors.
    Type: Grant
    Filed: June 21, 2005
    Date of Patent: September 5, 2006
    Assignee: Bristol-Myers Squibb Company
    Inventors: Ashvinikumar V. Gavai, Harold Mastalerz, Jean-Paul Daris, Pierre Dextraze, Philippe Lapointe, Edward H. Ruediger, Dolatrai M. Vyas, Guifen Zhang
  • Publication number: 20060014745
    Abstract: The present invention provides compounds of formula I and pharmaceutically acceptable salts thereof. The compounds of the invention inhibit tyrosine kinase activity of growth factor receptors such as HER1, HER2 and HER4 thereby making them useful as antiproliferative agents. The compounds are also useful for the treatment of other diseases associated with signal transduction pathways operating through growth factor receptors.
    Type: Application
    Filed: June 21, 2005
    Publication date: January 19, 2006
    Inventors: Ashvinikumar Gavai, Harold Mastalerz, Jean-Paul Daris, Pierre Dextraze, Philippe Lapointe, Edward Ruediger, Dolatrai Vyas, Guifen Zhang
  • Publication number: 20050209235
    Abstract: The present invention provides compounds of formula I and pharmaceutically acceptable salts thereof. The formula I compounds inhibit tyrosine kinase activity of growth factor receptors such as HER1, HER2 and HER4 thereby making them useful as antiproliferative agents. The formula I compounds are also useful for the treatment of other diseases associated with signal transduction pathways operating through growth factor receptors.
    Type: Application
    Filed: May 9, 2005
    Publication date: September 22, 2005
    Inventors: Harold Mastalerz, Guifen Zhang, James Tarrant, Gregory Vite
  • Patent number: 6908916
    Abstract: The present invention provides compounds of formula I and pharmaceutically acceptable salts thereof. The formula I compounds inhibit tyrosine kinase activity of growth factor receptors such as HER1, HER2 and HER4 thereby making them useful as antiproliferative agents. The formula I compounds are also useful for the treatment of other diseases associated with signal transduction pathways operating through growth factor receptors.
    Type: Grant
    Filed: November 14, 2002
    Date of Patent: June 21, 2005
    Assignee: Bristol Myers Squibb Company
    Inventors: Harold Mastalerz, Guifen Zhang, James G. Tarrant, Gregory D. Vite
  • Publication number: 20030186983
    Abstract: The present invention provides compounds of formula I 1
    Type: Application
    Filed: November 14, 2002
    Publication date: October 2, 2003
    Inventors: Harold Mastalerz, Guifen Zhang, James G. Tarrant, Gregory D. Vite