Patents by Inventor Guijie Zhu

Guijie Zhu has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 11768353
    Abstract: An optical imaging system includes an optical lens group including, sequentially along an optical axis from an object side to an image side, a first lens, a second lens, a third lens, and a fourth lens; a lens barrel, the optical lens group is accommodated in the lens barrel; and a plurality of spacers including at least two spacers disposed between the third lens and the fourth lens; the diameter D of the lens barrel at an end towards the object side and a maximum effective radius DT11 of an object-side surface of the first lens satisfy 2×DT11/D?0.5.
    Type: Grant
    Filed: September 21, 2020
    Date of Patent: September 26, 2023
    Assignee: ZHEJIANG SUNNY OPTICAL CO., LTD
    Inventors: Xiaofang Wang, Guijie Zhu, Biao Xu, Qi Chen, Kaiyuan Zhang, Fujian Dai, Liefeng Zhao
  • Publication number: 20230157845
    Abstract: A femoral neck measuring method includes: measuring an affected limb after a femoral stem prosthesis is installed through an optical localization probe, and calculating an actual length of the femoral neck needed by the affected limb according to an osteotomy surface of the affected limb determined after the femoral stem prosthesis is installed; determining a femoral ball prosthesis and a femoral neck prosthesis to be selected according to the calculated actual length of the femoral neck and a length of a femoral neck of a healthy limb measured before surgery; and measuring a length of the affected limb after the femoral ball prosthesis and the femoral neck prosthesis are implanted, and restraining a length difference between the healthy limb and the affected limb by adjusting a length of the femoral neck of the affected limb.
    Type: Application
    Filed: October 26, 2022
    Publication date: May 25, 2023
    Applicants: Shantou University, The First Affiliated Hospital of Shantou University Medical College
    Inventors: Zhun Fan, Weibo Ning, Jiazi Liu, Jiaqi Zhu, Guijie Zhu, Jun Hu, Hongjiang Chen, Jiacheng Liu, Zhifeng Hao
  • Publication number: 20210109317
    Abstract: An optical imaging system includes an optical lens group including, sequentially along an optical axis from an object side to an image side, a first lens, a second lens, a third lens, and a fourth lens; a lens barrel, the optical lens group is accommodated in the lens barrel; and a plurality of spacers including at least two spacers disposed between the third lens and the fourth lens; the diameter D of the lens barrel at an end towards the object side and a maximum effective radius DT11 of an object-side surface of the first lens satisfy 2×DT11/D?0.5.
    Type: Application
    Filed: September 21, 2020
    Publication date: April 15, 2021
    Inventors: Xiaofang WANG, Guijie ZHU, Biao XU, Qi CHEN, Kaiyuan ZHANG, Fujian DAI, Liefeng ZHAO
  • Patent number: 10578580
    Abstract: The invention provides a capillary isoelectric focusing (cIEF) system based on a sandwich injection method for automated chemical mobilization. This system was coupled with an electrokinetically pumped nanoelectrospray interface to a mass spectrometer. The nanoelectrospray emitter employed an acidic sheath electrolyte. To realize automated focusing and mobilization, a plug of ammonium hydroxide was first injected into the capillary, followed by a section of mixed sample and ampholyte. As focusing progressed, the NH3H2O section was titrated to lower pH buffer by the acidic sheath buffer. Chemical mobilization started automatically once the ammonium hydroxide was consumed by the acidic sheath flow electrolyte.
    Type: Grant
    Filed: September 22, 2017
    Date of Patent: March 3, 2020
    Assignee: University of Notre Dame du Lac
    Inventors: Norman Dovichi, Guijie Zhu, Liangliang Sun
  • Patent number: 10416115
    Abstract: A method of coating the inside wall of a capillary with a polymeric material for capillary electrophoresis is disclosed. The method can include introducing a catalyst-free solution of a monomer and initiator, wherein the monomer is present in about 1-10% (w/v) and the initiator is present in 0.1-1% (w/v), into a capillary and thermally initiating polymerization of the monomer thereby providing a capillary comprising an internal polymeric coating for separating, identifying, and quantifying components of an analyte.
    Type: Grant
    Filed: June 20, 2016
    Date of Patent: September 17, 2019
    Assignee: University of Nortre Dame du Lac
    Inventors: Norman Dovichi, Guijie Zhu, Liangliang Sun
  • Publication number: 20190004010
    Abstract: The invention provides a capillary isoelectric focusing (cIEF) system based on a sandwich injection method for automated chemical mobilization. This system was coupled with an electrokinetically pumped nanoelectrospray interface to a mass spectrometer. The nanoelectrospray emitter employed an acidic sheath electrolyte. To realize automated focusing and mobilization, a plug of ammonium hydroxide was first injected into the capillary, followed by a section of mixed sample and ampholyte. As focusing progressed, the NH3H2O section was titrated to lower pH buffer by the acidic sheath buffer. Chemical mobilization started automatically once the ammonium hydroxide was consumed by the acidic sheath flow electrolyte.
    Type: Application
    Filed: September 22, 2017
    Publication date: January 3, 2019
    Applicant: UNIVERSITY OF NOTRE DAME DU LAC
    Inventors: Norman DOVICHI, Guijie ZHU, Liangliang SUN
  • Publication number: 20170363576
    Abstract: The invention provides a novel method of coating the inside of a capillary with a polymeric material. The method can include introducing a catalyst-free solution of a monomer and initiator, wherein the monomer is present in about 1-10% (w/v) and the initiator is present in 0.1-1% (w/v), into a capillary and thermally initiating polymerization of the monomer thereby providing a capillary comprising an internal polymeric coating for separating, identifying, and quantifying components of an analyte.
    Type: Application
    Filed: June 20, 2016
    Publication date: December 21, 2017
    Applicant: University of Notre Dame du Lac
    Inventors: Norman DOVICHI, Guijie ZHU, Liangliang SUN
  • Patent number: 9465014
    Abstract: The invention provides a sheath-flow interface for producing electrospray from a capillary. The electrospray generated by the interface can be used as the source of ions for mass spectrometry. Electrokinetic flow in the interface can move a sheath liquid past the end of a capillary so as to mix with an analyte effluent discharged from the capillary. The sheath liquid and analyte mixture can be directed to an electrospray emitter to generate an electrospray.
    Type: Grant
    Filed: April 5, 2015
    Date of Patent: October 11, 2016
    Assignee: University of Notre Dame du Lac
    Inventors: Norman Dovichi, Liangliang Sun, Guijie Zhu
  • Patent number: 9362102
    Abstract: The invention provides a sheath-flow interface for producing electrospray from a capillary. The electrospray generated by the interface can be used as the source of ions for mass spectrometry. Electrokinetic flow in the interface can move a sheath liquid past the end of a capillary so as to mix with an analyte effluent discharged from the capillary. The sheath liquid and analyte mixture can be directed to an electrospray emitter to generate an electrospray.
    Type: Grant
    Filed: July 7, 2015
    Date of Patent: June 7, 2016
    Assignee: University of Notre Dame du Lac
    Inventors: Norman Dovichi, Liangliang Sun, Guijie Zhu
  • Publication number: 20150311056
    Abstract: The invention provides a sheath-flow interface for producing electrospray from a capillary. The electrospray generated by the interface can be used as the source of ions for mass spectrometry. Electrokinetic flow in the interface can move a sheath liquid past the end of a capillary so as to mix with an analyte effluent discharged from the capillary. The sheath liquid and analyte mixture can be directed to an electrospray emitter to generate an electrospray.
    Type: Application
    Filed: July 7, 2015
    Publication date: October 29, 2015
    Applicant: University of Notre Dame de Lac
    Inventors: Norman Dovichi, Liangliang Sun, Guijie Zhu
  • Patent number: 9159537
    Abstract: Described herein is a method and system for on-line coupling of capillary isoelectric focusing (cIEF) to high-resolution mass spectrometry in which a sheath flow buffer comprising polar organic solvent and organic acid is used as both an immobilization solution for (cIEF) and an ionization solution for electrospray ionization (ESI).
    Type: Grant
    Filed: May 2, 2013
    Date of Patent: October 13, 2015
    Assignees: University of Notre Dame du Lac, Medimmune, LLC
    Inventors: James McGivney, Guijie Zhu, Norman Dovichi
  • Publication number: 20150233877
    Abstract: The invention provides a sheath-flow interface for producing electrospray from a capillary. The electrospray generated by the interface can be used as the source of ions for mass spectrometry. Electrokinetic flow in the interface can move a sheath liquid past the end of a capillary so as to mix with an analyte effluent discharged from the capillary. The sheath liquid and analyte mixture can be directed to an electrospray emitter to generate an electrospray.
    Type: Application
    Filed: April 5, 2015
    Publication date: August 20, 2015
    Applicant: UNIVERSITY OF NOTRE DAME DU LAC
    Inventors: Norman Dovichi, Liangliang Sun, Guijie Zhu
  • Publication number: 20150162177
    Abstract: Described herein is a method and system for on-line coupling of capillary isoelectric focusing (cIEF) to high-resolution mass spectrometry in which a sheath flow buffer comprising polar organic solvent and organic acid is used as both an immobilization solution for (cIEF) and an ionization solution for electrospray ionization (ESI).
    Type: Application
    Filed: May 2, 2013
    Publication date: June 11, 2015
    Inventors: James McGivney, Guijie Zhu, Norman Dovichi