Patents by Inventor Guijie Zhu
Guijie Zhu has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Patent number: 11768353Abstract: An optical imaging system includes an optical lens group including, sequentially along an optical axis from an object side to an image side, a first lens, a second lens, a third lens, and a fourth lens; a lens barrel, the optical lens group is accommodated in the lens barrel; and a plurality of spacers including at least two spacers disposed between the third lens and the fourth lens; the diameter D of the lens barrel at an end towards the object side and a maximum effective radius DT11 of an object-side surface of the first lens satisfy 2×DT11/D?0.5.Type: GrantFiled: September 21, 2020Date of Patent: September 26, 2023Assignee: ZHEJIANG SUNNY OPTICAL CO., LTDInventors: Xiaofang Wang, Guijie Zhu, Biao Xu, Qi Chen, Kaiyuan Zhang, Fujian Dai, Liefeng Zhao
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Publication number: 20230157845Abstract: A femoral neck measuring method includes: measuring an affected limb after a femoral stem prosthesis is installed through an optical localization probe, and calculating an actual length of the femoral neck needed by the affected limb according to an osteotomy surface of the affected limb determined after the femoral stem prosthesis is installed; determining a femoral ball prosthesis and a femoral neck prosthesis to be selected according to the calculated actual length of the femoral neck and a length of a femoral neck of a healthy limb measured before surgery; and measuring a length of the affected limb after the femoral ball prosthesis and the femoral neck prosthesis are implanted, and restraining a length difference between the healthy limb and the affected limb by adjusting a length of the femoral neck of the affected limb.Type: ApplicationFiled: October 26, 2022Publication date: May 25, 2023Applicants: Shantou University, The First Affiliated Hospital of Shantou University Medical CollegeInventors: Zhun Fan, Weibo Ning, Jiazi Liu, Jiaqi Zhu, Guijie Zhu, Jun Hu, Hongjiang Chen, Jiacheng Liu, Zhifeng Hao
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Publication number: 20210109317Abstract: An optical imaging system includes an optical lens group including, sequentially along an optical axis from an object side to an image side, a first lens, a second lens, a third lens, and a fourth lens; a lens barrel, the optical lens group is accommodated in the lens barrel; and a plurality of spacers including at least two spacers disposed between the third lens and the fourth lens; the diameter D of the lens barrel at an end towards the object side and a maximum effective radius DT11 of an object-side surface of the first lens satisfy 2×DT11/D?0.5.Type: ApplicationFiled: September 21, 2020Publication date: April 15, 2021Inventors: Xiaofang WANG, Guijie ZHU, Biao XU, Qi CHEN, Kaiyuan ZHANG, Fujian DAI, Liefeng ZHAO
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Patent number: 10578580Abstract: The invention provides a capillary isoelectric focusing (cIEF) system based on a sandwich injection method for automated chemical mobilization. This system was coupled with an electrokinetically pumped nanoelectrospray interface to a mass spectrometer. The nanoelectrospray emitter employed an acidic sheath electrolyte. To realize automated focusing and mobilization, a plug of ammonium hydroxide was first injected into the capillary, followed by a section of mixed sample and ampholyte. As focusing progressed, the NH3H2O section was titrated to lower pH buffer by the acidic sheath buffer. Chemical mobilization started automatically once the ammonium hydroxide was consumed by the acidic sheath flow electrolyte.Type: GrantFiled: September 22, 2017Date of Patent: March 3, 2020Assignee: University of Notre Dame du LacInventors: Norman Dovichi, Guijie Zhu, Liangliang Sun
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Patent number: 10416115Abstract: A method of coating the inside wall of a capillary with a polymeric material for capillary electrophoresis is disclosed. The method can include introducing a catalyst-free solution of a monomer and initiator, wherein the monomer is present in about 1-10% (w/v) and the initiator is present in 0.1-1% (w/v), into a capillary and thermally initiating polymerization of the monomer thereby providing a capillary comprising an internal polymeric coating for separating, identifying, and quantifying components of an analyte.Type: GrantFiled: June 20, 2016Date of Patent: September 17, 2019Assignee: University of Nortre Dame du LacInventors: Norman Dovichi, Guijie Zhu, Liangliang Sun
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Publication number: 20190004010Abstract: The invention provides a capillary isoelectric focusing (cIEF) system based on a sandwich injection method for automated chemical mobilization. This system was coupled with an electrokinetically pumped nanoelectrospray interface to a mass spectrometer. The nanoelectrospray emitter employed an acidic sheath electrolyte. To realize automated focusing and mobilization, a plug of ammonium hydroxide was first injected into the capillary, followed by a section of mixed sample and ampholyte. As focusing progressed, the NH3H2O section was titrated to lower pH buffer by the acidic sheath buffer. Chemical mobilization started automatically once the ammonium hydroxide was consumed by the acidic sheath flow electrolyte.Type: ApplicationFiled: September 22, 2017Publication date: January 3, 2019Applicant: UNIVERSITY OF NOTRE DAME DU LACInventors: Norman DOVICHI, Guijie ZHU, Liangliang SUN
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Publication number: 20170363576Abstract: The invention provides a novel method of coating the inside of a capillary with a polymeric material. The method can include introducing a catalyst-free solution of a monomer and initiator, wherein the monomer is present in about 1-10% (w/v) and the initiator is present in 0.1-1% (w/v), into a capillary and thermally initiating polymerization of the monomer thereby providing a capillary comprising an internal polymeric coating for separating, identifying, and quantifying components of an analyte.Type: ApplicationFiled: June 20, 2016Publication date: December 21, 2017Applicant: University of Notre Dame du LacInventors: Norman DOVICHI, Guijie ZHU, Liangliang SUN
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Patent number: 9465014Abstract: The invention provides a sheath-flow interface for producing electrospray from a capillary. The electrospray generated by the interface can be used as the source of ions for mass spectrometry. Electrokinetic flow in the interface can move a sheath liquid past the end of a capillary so as to mix with an analyte effluent discharged from the capillary. The sheath liquid and analyte mixture can be directed to an electrospray emitter to generate an electrospray.Type: GrantFiled: April 5, 2015Date of Patent: October 11, 2016Assignee: University of Notre Dame du LacInventors: Norman Dovichi, Liangliang Sun, Guijie Zhu
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Patent number: 9362102Abstract: The invention provides a sheath-flow interface for producing electrospray from a capillary. The electrospray generated by the interface can be used as the source of ions for mass spectrometry. Electrokinetic flow in the interface can move a sheath liquid past the end of a capillary so as to mix with an analyte effluent discharged from the capillary. The sheath liquid and analyte mixture can be directed to an electrospray emitter to generate an electrospray.Type: GrantFiled: July 7, 2015Date of Patent: June 7, 2016Assignee: University of Notre Dame du LacInventors: Norman Dovichi, Liangliang Sun, Guijie Zhu
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Publication number: 20150311056Abstract: The invention provides a sheath-flow interface for producing electrospray from a capillary. The electrospray generated by the interface can be used as the source of ions for mass spectrometry. Electrokinetic flow in the interface can move a sheath liquid past the end of a capillary so as to mix with an analyte effluent discharged from the capillary. The sheath liquid and analyte mixture can be directed to an electrospray emitter to generate an electrospray.Type: ApplicationFiled: July 7, 2015Publication date: October 29, 2015Applicant: University of Notre Dame de LacInventors: Norman Dovichi, Liangliang Sun, Guijie Zhu
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Patent number: 9159537Abstract: Described herein is a method and system for on-line coupling of capillary isoelectric focusing (cIEF) to high-resolution mass spectrometry in which a sheath flow buffer comprising polar organic solvent and organic acid is used as both an immobilization solution for (cIEF) and an ionization solution for electrospray ionization (ESI).Type: GrantFiled: May 2, 2013Date of Patent: October 13, 2015Assignees: University of Notre Dame du Lac, Medimmune, LLCInventors: James McGivney, Guijie Zhu, Norman Dovichi
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Publication number: 20150233877Abstract: The invention provides a sheath-flow interface for producing electrospray from a capillary. The electrospray generated by the interface can be used as the source of ions for mass spectrometry. Electrokinetic flow in the interface can move a sheath liquid past the end of a capillary so as to mix with an analyte effluent discharged from the capillary. The sheath liquid and analyte mixture can be directed to an electrospray emitter to generate an electrospray.Type: ApplicationFiled: April 5, 2015Publication date: August 20, 2015Applicant: UNIVERSITY OF NOTRE DAME DU LACInventors: Norman Dovichi, Liangliang Sun, Guijie Zhu
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Publication number: 20150162177Abstract: Described herein is a method and system for on-line coupling of capillary isoelectric focusing (cIEF) to high-resolution mass spectrometry in which a sheath flow buffer comprising polar organic solvent and organic acid is used as both an immobilization solution for (cIEF) and an ionization solution for electrospray ionization (ESI).Type: ApplicationFiled: May 2, 2013Publication date: June 11, 2015Inventors: James McGivney, Guijie Zhu, Norman Dovichi