Patents by Inventor Guillaume Robert CARISSIMO

Guillaume Robert CARISSIMO has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • METHOD OF EVALUATING PROGRESSION OF AN INFECTIOUS DISEASE AND/OR INFLAMMATORY DISEASE
    Publication number: 20240369555
    Abstract: There is provided a method of evaluating risk of severe outcome of an infectious disease and/or an inflammatory disease in a patient, the method comprising: determining/measuring the number of one or more immune cells selected from the group consisting of VD2 T cells, CD8 T cells, and immature neutrophils in a sample obtained from the patient, wherein the patient has an enhanced risk of severe infectious disease and/or inflammatory disease outcome when: (i) the ratio of immature neutrophils to VD2 T cell is at least 2:1, and/or (ii) the ratio of immature neutrophils to CD8 T cell is at least 0.5:1. Also disclosed are method of treating a patient with a severe infectious disease and/or inflammatory disease and kit for use in methods thereof.
    Type: Application
    Filed: July 15, 2024
    Publication date: November 7, 2024
    Inventors: Guillaume Robert CARISSIMO, Immanuel Kwok Weng HAN, Weili XU, Lisa Fong Poh NG, Laurent RENIA, Anis LARBI, Lai Guan NG
  • Method of evaluating progression of an infectious disease and/or inflammatory disease
    Patent number: 12072335
    Abstract: There is provided a method of evaluating risk of severe outcome of an infectious disease and/or an inflammatory disease in a patient, the method comprising: determining/measuring the number of one or more immune cells selected from the group consisting of VD2 T cells, CD8 T cells, and immature neutrophils in a sample obtained from the patient, wherein the patient has an enhanced risk of severe infectious disease and/or inflammatory disease outcome when: (i) the ratio of immature neutrophils to VD2 T cell is at least 2:1, and/or (ii) the ratio of immature neutrophils to CD8 T cell is at least 0.5:1. Also disclosed are method of treating a patient with a severe infectious disease and/or inflammatory disease and kit for use in methods thereof.
    Type: Grant
    Filed: December 10, 2020
    Date of Patent: August 27, 2024
    Assignee: Agency for Science, Technology and Research
    Inventors: Guillaume Robert Carissimo, Immanuel Kwok Weng Han, Weili Xu, Lisa Fong Poh Ng, Laurent Renia, Anis Larbi, Lai Guan Ng
  • METHOD OF EVALUATING PROGRESSION OF AN INFECTIOUS DISEASE AND/OR INFLAMMATORY DISEASE
    Publication number: 20220187296
    Abstract: There is provided a method of evaluating risk of severe outcome of an infectious disease and/or an inflammatory disease in a patient, the method comprising: determining/measuring the number of one or more immune cells selected from the group consisting of VD2 T cells, CD8 T cells, and immature neutrophils in a sample obtained from the patient, wherein the patient has an enhanced risk of severe infectious disease and/or inflammatory disease outcome when: (i) the ratio of immature neutrophils to VD2 T cell is at least 2:1, and/or (ii) the ratio of immature neutrophils to CD8 T cell is at least 0.5:1. Also disclosed are method of treating a patient with a severe infectious disease and/or inflammatory disease and kit for use in methods thereof.
    Type: Application
    Filed: December 10, 2020
    Publication date: June 16, 2022
    Inventors: Guillaume Robert CARISSIMO, Immanuel Kwok Weng HAN, Weili XU, Lisa Fong Poh NG, Laurent RENIA, Anis LARBI, Lai Guan NG