Abstract: The present invention relates to a three-dimensional bioprinter for printing and/or patterning a single type or multiple types of cells into different geometrical arrangements and other three-dimensional structures, such as tissues. The bioprinter comprises multiple heads that can each be loaded with a different cartridge containing a biomaterial or biological material such as cells in a solution or cells in a hydrogel. Each bioprinter head and cartridge has the ability to heat or cool using Peltier technology. The bioprinter also has the ability to auto calibrate on a bed plate configured to accept a petri dish or microtiter plate.

Abstract: The present invention relates to a three-dimensional bioprinter for printing and/or patterning a single type or multiple types of cells into different geometrical arrangements and other three-dimensional structures, such as tissues. The bioprinter comprises multiple heads that can each be loaded with a different cartridge containing a biomaterial or biological material such as cells in a solution or cells in a hydrogel. Each bioprinter head and cartridge has the ability to heat or cool using Peltier technology. The bioprinter also has the ability to auto calibrate on a bed plate configured to accept a petri dish or microtiter plate.

Abstract: A chalk vending machine or apparatus and a method of vending chalk are provided. A reservoir is used to store the chalk. A feeder is used to transfer the chalk from the reservoir to the customer. A payment system allows the customer to pay for the product. A mixer is added to prevent the chalk from self-compacting. Motion transfer and generation devices are used to actuate the feeder. Accessories such as a door and a window for the reservoir and a chute and tray for the feeder are added to enhance the usability of the apparatus.