Patents by Inventor Guillermo Leon

Guillermo Leon has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 10562958
    Abstract: A method for producing injectable pharmaceutical formulations of blood-derived protein materials includes the steps of fractioning the source material in a polymer/salt aqueous two-phase system in the presence of phenol, purifying the top phase of the system by means of precipitation with caprylic acid and purifying the bottom phase by means of thermocoagulation, increasing the purity of the materials in both phases through chromatography, removing viral particles by means of the nanofiltration of both preparations, and formulating, stabilizing, and packaging the resulting materials.
    Type: Grant
    Filed: April 8, 2011
    Date of Patent: February 18, 2020
    Assignee: UNIVERSIDAD DE COSTA RICA
    Inventors: Álvaro Segura Ruiz, Mariángela Vargas Arroyo, Guillermo León Montero, Mauren Villalta Arrieta, María Herrera Vega, Yamileth Angulo Ugalde
  • Publication number: 20190192418
    Abstract: Pure saponins and processes for making such saponins are described herein. In addition, cosmetic compositions, such as skin care compositions, comprising such saponins and methods for improving skin health and appearance with such skincare compositions are also described herein.
    Type: Application
    Filed: March 1, 2019
    Publication date: June 27, 2019
    Applicant: BIOPROCOL, BIOPROCESOS DE COLOMBIA SAS
    Inventors: German Alfredo SCHAFER ELEJALDE, Guillermo Leon PALACIO GONZALEZ, Carlos Esteban ARISTIZABAL ALZATE
  • Patent number: 10265264
    Abstract: Pure saponins and processes for making such saponins are described herein. In addition, cosmetic compositions, such as skin care compositions, comprising such saponins and methods for improving skin health and appearance with such skincare compositions are also described herein.
    Type: Grant
    Filed: December 1, 2015
    Date of Patent: April 23, 2019
    Assignee: BIOPROCOL, BIOPROCESOS DE COLOMBIA SAS
    Inventors: German Alfredo Schafer Elejalde, Guillermo Leon Palacio Gonzalez, Carlos Esteban Aristizabal Alzate
  • Patent number: 10031184
    Abstract: The present invention discloses a method for the detection and diagnosis of faults in running electric machines.
    Type: Grant
    Filed: March 4, 2014
    Date of Patent: July 24, 2018
    Assignees: Universidad Nacional de Colombia, Empresas Publicas de Medellin E.S.P.
    Inventors: Raúl Esteban Jimenez Mejia, Guillermo León Mesa Betancur
  • Publication number: 20170348222
    Abstract: Pure saponins and processes for making such saponins are described herein. In addition, cosmetic compositions, such as skin care compositions, comprising such saponins and methods for improving skin health and appearance with such skincare compositions are also described herein.
    Type: Application
    Filed: December 1, 2015
    Publication date: December 7, 2017
    Inventors: German Alfredo SCHAFER ELEJALDE, Guillermo Leon PALACIO GONZALEZ, Carlos Esteban ARISTIZABAL ALZATE
  • Publication number: 20160150789
    Abstract: The present invention relates to an efficient process to obtain a Saponin and Sapogenin rich extract from fruits of Sonalum genus plants. The process presents a rational consumption of raw materials and energy resources, including polarity modifying agents which facilitate extraction and purification processes, which in turn increases its efficiency. The obtained Solasodine glycosides have biological antitumor and antibiotic activity, and can be used as precursors for the synthesis of pharmaceuticals, as active ingredients in medicinal compositions, cosmetics, veterinary products and bioproducts.
    Type: Application
    Filed: March 17, 2015
    Publication date: June 2, 2016
    Inventors: German Alfredo Schafer Elejalde, Guillermo León Palacio González, Carlos Esteban Aristizábal Alzate
  • Publication number: 20160018467
    Abstract: The present invention discloses a method for the detection and diagnosis of faults in running electric machines.
    Type: Application
    Filed: March 4, 2014
    Publication date: January 21, 2016
    Inventors: Raúl Esteban JIMENEZ MEJIA, Guillermo León MESA BETANCUR
  • Publication number: 20140121357
    Abstract: A method for producing injectable pharmaceutical formulations of blood-derived protein materials includes the steps of fractioning the source material in a polymer/salt aqueous two-phase system in the presence of phenol, purifying the top phase of the system by means of precipitation with caprylic acid and purifying the bottom phase by means of thermocoagulation, increasing the purity of the materials in both phases through chromatography, removing viral particles by means of the nanofiltration of both preparations, and formulating, stabilizing, and packaging the resulting materials.
    Type: Application
    Filed: April 8, 2011
    Publication date: May 1, 2014
    Applicant: UNIVERSIDAD DE COSTA RICA
    Inventors: Alvaro Segura Ruiz, Mariángela Vargas Arroyo, Guillermo Leon Montero, Mauren Villalta Arrieta, Maria Herrera Vega, Yamileth Angulo Ugalde
  • Patent number: D806312
    Type: Grant
    Filed: October 28, 2015
    Date of Patent: December 26, 2017
    Assignee: LA AURORA S.A.
    Inventor: Guillermo Leon