Patents by Inventor Guillermo Leon Montero

Guillermo Leon Montero has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Method for producing injectable formulations of blood-derived protein materials, and materials obtained using said method
    Patent number: 10562958
    Abstract: A method for producing injectable pharmaceutical formulations of blood-derived protein materials includes the steps of fractioning the source material in a polymer/salt aqueous two-phase system in the presence of phenol, purifying the top phase of the system by means of precipitation with caprylic acid and purifying the bottom phase by means of thermocoagulation, increasing the purity of the materials in both phases through chromatography, removing viral particles by means of the nanofiltration of both preparations, and formulating, stabilizing, and packaging the resulting materials.
    Type: Grant
    Filed: April 8, 2011
    Date of Patent: February 18, 2020
    Assignee: UNIVERSIDAD DE COSTA RICA
    Inventors: Álvaro Segura Ruiz, Mariángela Vargas Arroyo, Guillermo León Montero, Mauren Villalta Arrieta, María Herrera Vega, Yamileth Angulo Ugalde
  • METHOD FOR PRODUCING INJECTABLE FORMULATIONS OF BLOOD-DERIVED PROTEIN MATERIALS, AND MATERIALS OBTAINED USING SAID METHOD
    Publication number: 20140121357
    Abstract: A method for producing injectable pharmaceutical formulations of blood-derived protein materials includes the steps of fractioning the source material in a polymer/salt aqueous two-phase system in the presence of phenol, purifying the top phase of the system by means of precipitation with caprylic acid and purifying the bottom phase by means of thermocoagulation, increasing the purity of the materials in both phases through chromatography, removing viral particles by means of the nanofiltration of both preparations, and formulating, stabilizing, and packaging the resulting materials.
    Type: Application
    Filed: April 8, 2011
    Publication date: May 1, 2014
    Applicant: UNIVERSIDAD DE COSTA RICA
    Inventors: Alvaro Segura Ruiz, Mariángela Vargas Arroyo, Guillermo Leon Montero, Mauren Villalta Arrieta, Maria Herrera Vega, Yamileth Angulo Ugalde