Patents by Inventor Guillermo Llamazares Prieto

Guillermo Llamazares Prieto has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 11142734
    Abstract: The present invention relates to a novel microfluidic device and a microfluidic system for culturing cell samples based on: one or more culture wells (2) forming cell housing volumes for three-dimensional cell culture; one or more capillary channels (1) for circulating cells and/or fluid media, said channels (1) being connected to the wells (2) as well perfusion means; and an inlet port (3) and an outlet port (3?) for seeding cells and/or for circulating fluid in said channel (1), said ports (3, 3?) being connected to the ends of each capillary channel (1). The novel configuration of the ports (3, 3?) and their corresponding channels (1) allows known microfluidic perfusion media to be improved, dispensing with the use of complex elements for injecting the fluid media, such as syringe pumps, for example. The invention also allows two-dimensional and three-dimensional culture studies to be performed simultaneously.
    Type: Grant
    Filed: November 4, 2016
    Date of Patent: October 12, 2021
    Assignees: UNIVERSIDAD DE ZARAGOZA, CENTRO DE INVESTIGACIÓN BIOMÉDICA EN RED (CIBER)
    Inventors: Luis J. Fernández Ledesma, Rosa Monge Prieto, Guillermo Llamazares Prieto, José María Ayuso Domínguez, María Virumbrales Muñoz, Jorge Santolaria Mazo, Ignacio Ochoa Garrido
  • Publication number: 20180327701
    Abstract: The present invention relates to a novel microfluidic device and a microfluidic system for culturing cell samples based on: one or more culture wells (2) forming cell housing volumes for three-dimensional cell culture; one or more capillary channels (1) for circulating cells and/or fluid media, said channels (1) being connected to the wells (2) as well perfusion means; and an inlet port (3) and an outlet port (3?) for seeding cells and/or for circulating fluid in said channel (1), said ports (3, 3?) being connected to the ends of each capillary channel (1). The novel configuration of the ports (3, 3?) and their corresponding channels (1) allows known microfluidic perfusion media to be improved, dispensing with the use of complex elements for injecting the fluid media, such as syringe pumps, for example. The invention also allows two-dimensional and three-dimensional culture studies to be performed simultaneously.
    Type: Application
    Filed: November 4, 2016
    Publication date: November 15, 2018
    Inventors: Luis J. Fernandez Ledesma, Rosa Monge Prieto, Guillermo Llamazares Prieto, Jose Maria Ayuso Dominguez, Maria Virumbrales Munoz, Jorge Santolaria Mazo, Ignacio Ochoa Garrido