Abstract: A method for computational drug target selection includes ingesting publication data from at least one publication data source, the publication data relating to a plurality of publication documents including historical publication documents and current publication documents. The method includes searching the publication data to provide an indication, for each of the publication documents, as to whether the respective publication document is associated with one or more drug targets. The method includes determining an expected publication parameter for each of the one or more drug targets based on the searched publication data from the historical publication documents, and determining an actual publication parameter for each of the one or more drug targets based on the searched publication data from the current publication documents. The method includes evaluating each of the one or more drug targets for selection based on its actual publication parameter relative to its expected publication parameter.

Abstract: Vital sign monitors are plagued by noisy photoplethysmography (PPG) data, making it difficult for the monitors to output consistently accurate readings. Noise in PPG signals is often caused by motion. The present disclosure provides improved techniques for reducing motion-related artifacts in optical/PPG measurements for vital signs monitoring. In general, techniques described herein are based on using measurements of reference sensors that include sensors other than optical sensors used for the optical measurements, e.g., biopotential sensors, bioimpedance sensors, and/or capacitive sensors. In particular, techniques described herein aim to filter PPG signals using substantially only the noise components of signals generated by reference sensors, by attenuating or altogether eliminating components of the signals generated by reference sensors which are indicative of the parameter the reference sensors are designed to measure.

Abstract: Vital sign monitors are plagued by noisy photoplethysmography (PPG) data, making it difficult for the monitors to output consistently accurate readings. Noise in PPG signals is often caused by motion. The present disclosure provides improved techniques for reducing motion-related artifacts in optical/PPG measurements for vital signs monitoring. In general, techniques described herein are based on using measurements of reference sensors that include sensors other than optical sensors used for the optical measurements, e.g., biopotential sensors, bioimpedance sensors, and/or capacitive sensors. In particular, techniques described herein aim to filter PPG signals using substantially only the noise components of signals generated by reference sensors, by attenuating or altogether eliminating components of the signals generated by reference sensors which are indicative of the parameter the reference sensors are designed to measure.

Abstract: An operational amplifier including: a differential pair of transistors coupled to a pair of input signals; and a pair of floating-gate transistors coupled to the differential pair of transistors, wherein the pair of floating-gate transistors are operable for reducing an offset voltage of the operational amplifier.

Abstract: An operational amplifier including: a differential pair of transistors coupled to a pair of input signals; and a pair of floating-gate transistors coupled to the differential pair of transistors, wherein the pair of floating-gate transistors are operable for reducing an offset voltage of the operational amplifier.

Abstract: An operational amplifier including: a differential pair of transistors coupled to a pair of input signals; and a pair of floating-gate transistors coupled to the differential pair of transistors, wherein the pair of floating-gate transistors are operable for reducing an offset voltage of the operational amplifier.

Abstract: An operational amplifier including: a differential pair of transistors coupled to a pair of input signals; and a pair of floating-gate transistors coupled to the differential pair of transistors, wherein the pair of floating-gate transistors are operable for reducing an offset voltage of the operational amplifier.

Abstract: Systems and methods are discussed for using a floating-gate MOSFET as a programmable reference circuit. One example of the programmable reference circuit is a programmable voltage reference source, while a second example of a programmable reference circuit is a programmable reference current source. The programmable voltage reference source and/or the reference current source may be incorporated into several types of circuits, such as comparator circuits, current-mirror circuits, and converter circuits. Comparator circuits and current-mirror circuits are often incorporated into circuits such as converter circuits. Converter circuits include analog-to-digital converters and digital-to-analog converters.

Abstract: Systems and methods are discussed for using a floating-gate MOSFET as a programmable reference circuit. One example of the programmable reference circuit is a programmable voltage reference source, while a second example of a programmable reference circuit is a programmable reference current source. The programmable voltage reference source and/or the reference current source may be incorporated into several types of circuits, such as comparator circuits, current-mirror circuits, and converter circuits. Comparator circuits and current-mirror circuits are often incorporated into circuits such as converter circuits. Converter circuits include analog-to-digital converters and digital-to-analog converters.