Patents by Inventor Guillerno Corrales Morales

Guillerno Corrales Morales has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Enzymatic method of producing 4-O-?-D-galactopyranosyl-D-xylose, 4-O-?-D-galactopyranosyl-D-xylose obtained using said method, compositions contain same and the use thereof in evaluating intestinal lactase
    Patent number: 7537909
    Abstract: An enzymatic process to obtain 4-O-?-D-galactopyranosyl-D-xylose useful in compositions or solutions in the in vivo evaluation of intestinal lactose activity in humans, that comprises the steps of preparing a reaction mixture of D-xylose, a ?-D-galactopyranoside and a reaction medium that comprises water buffered to a pH between 5.0 and 9.0; adding 10 to 1,000 units of ?-D-galactosidase per gram of ?-D-galactopyranoside; subjecting the reaction mixture to a reaction or a temperature between a temperature higher than the freezing point of the reaction mixture and 45° C., for 2 to 48 hours; for the reaction by deactivation of the ?-D-galactosidase; and to isolate and crystallize the fractions that contain 4-O-?-D-galactopyranosyl-D-xylose from a crystallization mixture selected between mixtures of acetone/methanol in a ratio between 5/1 to 20/1 and mixtures of acetone/water in a ratio between 5/1 to 20/1.
    Type: Grant
    Filed: December 17, 2003
    Date of Patent: May 26, 2009
    Assignees: Consejo Superior de Investigaciones Cientificas, Universidad Autonoma de Madrid
    Inventors: Francisco Javier Cañada Vicinay, Guillerno Corrales Morales, Alfonso Fernández-Mayoralas Alvarez, Manuel Martín Lomas, Juan José Aragón Reyes
  • Enzymatic method of producing 4-O-B-D-galactopyranosyl-D-xylose, 4-O-B-D-galactopyranosyl-D-xylose obtained using said method, compositions contain same and the use thereof in evaluating intestinal lactase
    Publication number: 20040241811
    Abstract: An enzymatic process to obtain 4-O-&bgr;-D-galactopyranosyl-D-xylose useful in compositions or solutions in the in vivo evaluation of intestinal lactose activity in humans, that comprises the steps of preparing a reaction mixture of D-xylose, a &bgr;-D-galactopyranoside and a reaction medium that comprises water buffered to a pH between 5.0 and 9.0; adding 10 to 1,000 units of &bgr;-D-galactosidase per gram of &bgr;-D-galactopyranoside; subjecting the reaction mixture to a reaction or a temperature between a temperature higher than the freezing point of the reaction mixture and 45° C., for 2 to 48 hours; for the reaction by deactivation of the &bgr;-D-galactosidase; and to isolate and crystallize the fractions that contain 4-O-&bgr;-D-galactopyranosyl-D-xylose from a crystallization mixture selected between mixtures of acetone/methanol in a ratio between 5/1 to 20/1 and mixtures of acetone/water in a ratio between 5/1 to 20/1.
    Type: Application
    Filed: December 17, 2003
    Publication date: December 2, 2004
    Inventors: Francisco Javier Canada Vicinay, Guillerno Corrales Morales, Alfonso Fernandez-Mayorales Alvarez, Manuel Martin Lomas, Juan Jose Aragon Reyes