Patents by Inventor Guishao TANG

Guishao TANG has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Diglycosylated benzophenoxazine photosensitizer and preparation method and use thereof
    Patent number: 11357852
    Abstract: Disclosed are a diglycosylated benzophenoxazine photosensitizer, and a preparation method and use thereof. The present invention greatly improves the enriched concentration of the photosensitizer in tumor cells by taking full advantage of the enhanced uptake and enhanced glycolysis of carbohydrates by tumor cells and the glycosylation of a selenium-containing benzophenoxazine compound, thereby improving the targeting of a diglycosylated benzophenoxazine photosensitizer involved in the present invention in the treatment of cutaneous tumors and also significantly decreasing the toxic and side effects of the photodynamic therapy. The present invention can efficiently and rapidly inhibit the proliferation of cells of cutaneous squamous cell carcinoma and essentially cause no damage to normal cells.
    Type: Grant
    Filed: November 16, 2017
    Date of Patent: June 14, 2022
    Assignee: The Third Xiangva Hospital of Central South University
    Inventors: Jing Chen, Jinhua Huang, Jian Kang, Zhen Wang, An Liu, Xiangzhi Song, Kehua Guo, Siqi Ma, Jian Huang, Liyang Kang, Chengxin Zuo, Shengbo Yang, Yihao Li, Jiahao Li, Jiayao Pan, Guishao Tang
  • DIGLYCOSYLATED BENZOPHENOXAZINE PHOTOSENSITIZER AND PREPARATION METHOD AND USE THEREOF
    Publication number: 20200297846
    Abstract: Disclosed are a diglycosylated benzophenoxazine photosensitizer, and a preparation method and use thereof. The present invention greatly improves the enriched concentration of the photosensitizer in tumor cells by taking full advantage of the enhanced uptake and enhanced glycolysis of carbohydrates by tumor cells and the glycosylation of a selenium-containing benzophenoxazine compound, thereby improving the targeting of a diglycosylated benzophenoxazine photosensitizer involved in the present invention in the treatment of cutaneous tumors and also significantly decreasing the toxic and side effects of the photodynamic therapy. The present invention can efficiently and rapidly inhibit the proliferation of cells of cutaneous squamous cell carcinoma and essentially cause no damage to normal cells.
    Type: Application
    Filed: November 16, 2017
    Publication date: September 24, 2020
    Inventors: Jing CHEN, Jinhua HUANG, Jian KANG, Zhen WANG, An LIU, Xiangzhi SONG, Kehua GUO, Siqi MA, Jian HUANG, Liyang KANG, Chengxin ZUO, Shengbo YANG, Yihao LI, Jiahao LI, Jiayao PAN, Guishao TANG