Patents by Inventor Guisheng Zhang

Guisheng Zhang has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Etomidate derivative and intermediate, preparation method and use thereof
    Patent number: 10392352
    Abstract: The present invention discloses an etomidate derivative of Formula 1, or a pharmaceutically acceptable salt, a polymorph, or a solvate thereof, a pharmaceutical composition and a kit comprising the same, as well as intermediates and methods for preparing the same, and use thereof. The etomidate derivative of the present invention not only has good anesthetic activity, rapid onset, and short duration of action, but also shows little inhibition to the secretion of corticosteroids in animals, and therefore has both favorable anesthetic effect and safety profiles.
    Type: Grant
    Filed: October 10, 2016
    Date of Patent: August 27, 2019
    Assignee: JIANGSU NHWALUOKANG PHARMCEUTICAL RESEARCH AND DEVELOPMENT CO., LTD.
    Inventors: Qingeng Li, Tao Wang, Lingguo Zeng, Guisheng Zhang, Xiangqing Xu, Liang Ren
  • ETOMIDATE DERIVATIVE AND INTERMEDIATE, PREPARATION METHOD AND USE THEREOF
    Publication number: 20180297958
    Abstract: The present invention discloses an etomidate derivative of Formula 1, or a pharmaceutically acceptable salt, a polymorph, or a solvate thereof, a pharmaceutical composition and a kit comprising the same, as well as intermediates and methods for preparing the same, and use thereof. The etomidate derivative of the present invention not only has good anesthetic activity, rapid onset, and short duration of action, but also shows little inhibition to the secretion of corticosteroids in animals, and therefore has both favorable anesthetic effect and safety profiles.
    Type: Application
    Filed: October 10, 2016
    Publication date: October 18, 2018
    Inventors: Qingeng Li, Tao Wang, Lingguo Zeng, Guisheng Zhang, Xiangqing Xu, Liang Ren
  • Multidrug resistant anticancer anthracyclines
    Patent number: 7737123
    Abstract: Daunorubicin (“DNR”) compounds synthesized with uncommon sugars exhibit enhanced effectiveness in treating various drug-resistant cancers.
    Type: Grant
    Filed: May 12, 2006
    Date of Patent: June 15, 2010
    Assignee: The Ohio State University Research Foundation
    Inventors: Guisheng Zhang, Lanyan Fang, Peng George Wang, Duxin Sun
  • Multidrug resistant anticancer anthracyclines
    Publication number: 20060276418
    Abstract: Daunorubicin (“DNR”) compounds synthesized with uncommon sugars exhibit enhanced effectiveness in treating various drug-resistant cancers.
    Type: Application
    Filed: May 12, 2006
    Publication date: December 7, 2006
    Applicant: The Ohio State University Research Foundation
    Inventors: Guisheng Zhang, Lanyan Fang, Peng Wang, Duxin Sun