Patents by Inventor Guixia Hao

Guixia Hao has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Optimized thionin protects plants against bacterial infections
    Patent number: 10378024
    Abstract: Two small proteins with anti-bacterial activity are generated and called optimized thionin and optimized pro-thionin. Optimized pro-thionin contains a signal sequence for intracellular trafficking of the protein and is cleaved off to yield optimized thionin. Genetically altered plants and their progeny expressing a polynucleotide encoding optimized pro-thionin or optimized thionin resist diseases caused by bacteria.
    Type: Grant
    Filed: June 29, 2017
    Date of Patent: August 13, 2019
    Assignee: The United States of America, as Represented by the Secretary of Agriculture
    Inventors: Eddie W Stover, Goutam Gupta, Guixia Hao
  • OPTIMIZED THIONIN PROTECTS PLANTS AGAINST BACTERIAL INFECTIONS
    Publication number: 20170314038
    Abstract: Two small proteins with anti-bacterial activity are generated and called optimized thionin and optimized pro-thionin. Optimized pro-thionin contains a signal sequence for intracellular trafficking of the protein and is cleaved off to yield optimized thionin. Genetically altered plants and their progeny expressing a polynucleotide encoding optimized pro-thionin or optimized thionin resist diseases caused by bacteria.
    Type: Application
    Filed: June 29, 2017
    Publication date: November 2, 2017
    Inventors: Eddie W Stover, Goutam Gupta, Guixia Hao
  • Thionin-D4E1 chimeric protein protects plants against bacterial infections
    Patent number: 9725734
    Abstract: The generation of a chimeric protein containing a first domain encoding either a pro-thionon or thionin, a second domain encoding D4E1 or pro-D4E1, and a third domain encoding a peptide linker located between the first domain and second domain is described. Either the first domain or the second domain is located at the amino terminal of the chimeric protein and the other domain (second domain or first domain, respectively) is located at the carboxyl terminal. The chimeric protein has antibacterial activity. Genetically altered plants and their progeny expressing a polynucleotide encoding the chimeric protein resist diseases caused by bacteria.
    Type: Grant
    Filed: April 21, 2015
    Date of Patent: August 8, 2017
    Assignees: The United States of America, as represented by the Secretary of Agriculture, Los Alamos National Security, LLC
    Inventors: Eddie W Stover, Goutam Gupta, Guixia Hao
  • THIONIN-D4E1 CHIMERIC PROTEIN PROTECTS PLANTS AGAINST BACTERIAL INFECTIONS
    Publication number: 20160312241
    Abstract: The generation of a chimeric protein containing a first domain encoding either a pro-thionon or thionin, a second domain encoding D4E1 or pro-D4E1, and a third domain encoding a peptide linker located between the first domain and second domain is described. Either the first domain or the second domain is located at the amino terminal of the chimeric protein and the other domain (second domain or first domain, respectively) is located at the carboxyl terminal. The chimeric protein has antibacterial activity. Genetically altered plants and their progeny expressing a polynucleotide encoding the chimeric protein resist diseases caused by bacteria.
    Type: Application
    Filed: April 21, 2015
    Publication date: October 27, 2016
    Inventors: Eddie W Stover, Goutam X Gupta, Guixia Hao