Abstract: The present application discloses a surgical instrument. The surgical instrument includes an end effector, a connecting assembly, and a tip driving unit. The connecting assembly includes a plurality of connecting units connected in sequence, and the end effector is connected to the connecting assembly. The tip driving unit includes a flexible rod and a driving wire, the driving wire extends out of the flexible rod and is connected to the end effector. The flexible rod extends through the connecting assembly, and at least one end of the flexible rod is a free end. Due to the flexible rod, friction of the driving wire in a moving state can be reduced, thereby a life of the driving wire can be prolonged, and an accurate movement of the driving wire can be maintained.