Patents by Inventor Guiyuan Lei

Guiyuan Lei has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • GENE EXPRESSION MARKERS FOR PREDICTING RESPONSE TO INTERLEUKIN-6 RECEPTOR-INHIBITING MONOCLONAL ANTIBODY DRUG TREATMENT
    Publication number: 20120009177
    Abstract: This invention provides methods, compositions, and kits relating to gene product biomarkers where gene expression levels are correlated with therapeutic response of rheumatoid arthritis patients to treatment with an IL-6 receptor antagonist, such as an IL6-R antibody. The methods, compositions, and kits of the invention can be used to identify rheumatoid arthritis patients who are likely, or not likely, to respond to IL-6 receptor antagonist treatments.
    Type: Application
    Filed: June 6, 2011
    Publication date: January 12, 2012
    Applicant: Roche Molecular Systems, Inc.
    Inventors: Adam Platt, Jianmei Wang, Guiyuan Lei, Laurent Essioux, Wei-min Liu, P. Mickey Williams