Patents by Inventor Gulsu Sener Yildirim

Gulsu Sener Yildirim has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Sustained release of bioactive factors from zwitterionic hydrogels
    Patent number: 10653783
    Abstract: Methods of producing microporous zwitterionic cryogels are described, wherein the cryogels are useful for sustaining release of therapeutic agents. The disclosed cryogels overcome several limitations associated with existing compositions, for example the disclosed cryogels have high loading efficiencies and a sustained release profile with minimal burst of up to 4 months or more. The characteristics of the disclosed cryogels can be varied by altering monomer (e.g. zwitterion) and crosslinker selection. The amount of monomer contained in the hydrogel may also be varied to aid in controlling the cryogel's chemistry.
    Type: Grant
    Filed: November 9, 2017
    Date of Patent: May 19, 2020
    Inventors: Melissa D. Krebs, Gulsu Sener Yildirim
  • SUSTAINED RELEASE OF BIOACTIVE FACTORS FROM ZWITTERIONIC HYDROGELS
    Publication number: 20180221490
    Abstract: Methods of producing microporous zwitterionic cryogels are described, wherein the cryogels are useful for sustaining release of therapeutic agents. The disclosed cryogels overcome several limitations associated with existing compositions, for example the disclosed cryogels have high loading efficiencies and a sustained release profile with minimal burst of up to 4 months or more. The characteristics of the disclosed cryogels can be varied by altering monomer (e.g. zwitterion) and crosslinker selection. The amount of monomer contained in the hydrogel may also be varied to aid in controlling the cryogel's chemistry.
    Type: Application
    Filed: November 9, 2017
    Publication date: August 9, 2018
    Inventors: Melissa D. Krebs, Gulsu Sener Yildirim