Abstract: A computer-implemented method for forming a search query includes receiving a search request for searching at least one output document based on a first input document, extract a first metadata from the first input document, a second metadata from at least one second input document, and a third metadata from synonyms of the first and second metadata, form a first set of metadata by combining the first, second and third metadata, rank a first set of categories, wherein a category associated with a highest number of input documents is ranked highest, forming a second set of categories by excluding a predefined number of categories, forming a second set of metadata by excluding at least one definition metadata from the first set of metadata, and forming a search query by combining the second set of metadata and second set of categories.

Abstract: A computer-implemented method for forming a search query includes receiving a search request for searching at least one output document based on a first input document, extract a first metadata from the first input document, a second metadata from at least one second input document, and a third metadata from synonyms of the first and second metadata, form a first set of metadata by combining the first, second and third metadata, rank a first set of categories, wherein a category associated with a highest number of input documents is ranked highest, forming a second set of categories by excluding a predefined number of categories, forming a second set of metadata by excluding at least one definition metadata from the first set of metadata, and forming a search query by combining the second set of metadata and second set of categories.

Abstract: A process for the resolution of isomeric tramadol mixtures comprising: providing a purification stock comprising both cis and trans tramadol; contacting the purification stock with an acid under conditions effective to form an acid salt of the cis and trans tramadol in the purification stock; and separating the cis tramadol acid salt from the trans tramadol to obtain a purified cis tramadol acid salt; and optionally converting the cis tramadol acid salt to cis tramadol or to a pharmaceutically active salt thereof.

Abstract: Disclosed herein is a process for preparation of carvedilol substantially free from its bis-impurity comprises the reaction of 4-(2,3-epoxypropoxy)carbazole and 2-(2-methoxyphenoxy)ethylamine in a polar aprotic solvent media; followed by isolation of carvediol from the reaction mass as an acid addition salt and subsequent conversion into pure carvedilol.