Patents by Inventor Gunnar James Hanson

Gunnar James Hanson has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • ANTISENSE-INDUCED EXON2 INCLUSION IN ACID ALPHA-GLUCOSIDASE
    Publication number: 20220170024
    Abstract: The present disclosure relates to antisense oligomers and related compositions and methods for inducing exon inclusion as a treatment for glycogen storage disease type II (GSD-II) (also known as Pompe disease, glycogenosis II, acid maltase deficiency (AMD), acid alpha-glucosidase deficiency, and lysosomal alpha-glucosidase deficiency), and more specifically relates to inducing inclusion of exon 2 and thereby restoring levels of enzymatically active acid alpha-glucosidase (GAA) protein encoded by the GAA gene.
    Type: Application
    Filed: December 15, 2021
    Publication date: June 2, 2022
    Inventors: Stephen Donald WILTON, Sue FLETCHER, Gunnar James HANSON, Richard Keith BESTWICK
  • Antisense-induced exon2 inclusion in acid alpha-glucosidase
    Patent number: 11236338
    Abstract: The present disclosure relates to antisense oligomers and related compositions and methods for inducing exon inclusion as a treatment for glycogen storage disease type II (GSD-II) (also known as Pompe disease, glycogenosis II, acid maltase deficiency (AMD), acid alpha-glucosidase deficiency, and lysosomal alpha-glucosidase deficiency), and more specifically relates to inducing inclusion of exon 2 and thereby restoring levels of enzymatically active acid alpha-glucosidase (GAA) protein encoded by the GAA gene.
    Type: Grant
    Filed: September 5, 2014
    Date of Patent: February 1, 2022
    Assignees: SAREPTA THERAPEUTICS, INC., MURDOCH UNIVERSITY
    Inventors: Stephen Donald Wilton, Sue Fletcher, Gunnar James Hanson, Richard Keith Bestwick
  • ANTISENSE-INDUCED EXON2 INCLUSION IN ACID ALPHA-GLUCOSIDASE
    Publication number: 20180216111
    Abstract: The present disclosure relates to antisense oligomers and related compositions and methods for inducing exon inclusion as a treatment for glycogen storage disease type II (GSD-II) (also known as Pompe disease, glycogenosis II, acid maltase deficiency (AMD), acid alpha-glucosidase deficiency, and lysosomal alpha-glucosidase deficiency), and more specifically relates to inducing inclusion of exon 2 and thereby restoring levels of enzymatically active acid alpha-glucosidase (GAA) protein encoded by the GAA gene.
    Type: Application
    Filed: February 29, 2016
    Publication date: August 2, 2018
    Inventors: Stephen Donald WILTON, Sue FLETCHER, Gunnar James HANSON, Richard Keith BESTWICK, Frederick J. SCHNELL
  • ANTISENSE-INDUCED EXON2 INCLUSION IN ACID ALPHA-GLUCOSIDASE
    Publication number: 20160208264
    Abstract: The present disclosure relates to antisense oligomers and related compositions and methods for inducing exon inclusion as a treatment for glycogen storage disease type II (GSD-II) (also known as Pompe disease, glycogenosis II, acid maltase deficiency (AMD), acid alpha-glucosidase deficiency, and lysosomal alpha-glucosidase deficiency), and more specifically relates to inducing inclusion of exon 2 and thereby restoring levels of enzymatically active acid alpha-glucosidase (GAA) protein encoded by the GAA gene.
    Type: Application
    Filed: September 5, 2014
    Publication date: July 21, 2016
    Inventors: Stephen Donald Wilton, Sue Fletcher, Gunnar James Hanson, Richard Keith Bestwick
  • ANTISENSE-INDUCED EXON2 INCLUSION IN ACID ALPHA-GLUCOSIDASE
    Publication number: 20150197534
    Abstract: The present disclosure relates to antisense oligomers and related compositions and methods for inducing exon inclusion as a treatment for glycogen storage disease type II (GSD-II) (also known as Pompe disease, glycogenosis II, acid maltase deficiency (AMD), acid alpha-glucosidase deficiency, and lysosomal alpha-glucosidase deficiency), and more specifically relates to inducing inclusion of exon 2 and thereby restoring levels of enzymatically active acid alpha-glucosidase (GAA) protein encoded by the GAA gene.
    Type: Application
    Filed: September 5, 2014
    Publication date: July 16, 2015
    Inventors: Stephen Donald Wilton, Sue Fletcher, Gunnar James Hanson, Richard Keith Bestwick
  • Dimeric Smac Mimetics
    Publication number: 20130344026
    Abstract: The invention provides small molecule mimics of the Smac peptide that are dimers or dimer-like compounds having two binding domains connected by a linker. These compounds are useful to promote apoptosis. The invention includes pharmaceutical compositions comprising such compounds and methods to use them to treat conditions including cancer and autoimmune disorders.
    Type: Application
    Filed: August 22, 2013
    Publication date: December 26, 2013
    Inventors: Haizhou Sun, Xiaoming Xu, Ming Zhou, Susan Harran, Gunnar James Hanson, Lai Wang
  • Dimeric Smac mimetics
    Patent number: 8551955
    Abstract: The invention provides small molecule mimics of the Smac peptide that are dimers or dimer-like compounds having two binding domains connected by a linker. These compounds are useful to promote apoptosis. The invention includes pharmaceutical compositions comprising such compounds and methods to use them to treat conditions including cancer and autoimmune disorders.
    Type: Grant
    Filed: October 28, 2010
    Date of Patent: October 8, 2013
    Assignee: Joyant Pharmaceuticals, Inc.
    Inventors: Haizhou Sun, Xiaoming Xu, Ming Zhou, Susan Harran, Gunnar James Hanson, Lai Wang
  • Diazonamide analogs
    Patent number: 8476256
    Abstract: Novel diazonamide analogs having anti-mitotic activity, useful for the treatment of cancer and other proliferative disorders are provided.
    Type: Grant
    Filed: March 26, 2012
    Date of Patent: July 2, 2013
    Assignee: Joyant Pharmaceuticals, Inc.
    Inventors: Gunnar James Hanson, Ming Zhou, Qi Wei, Charles Caldwell
  • Indoline anti-cancer agents
    Patent number: 8334311
    Abstract: Indoline compounds having anti-mitotic activity, useful for the treatment of cancer and other proliferative disorders are provided.
    Type: Grant
    Filed: July 25, 2011
    Date of Patent: December 18, 2012
    Assignee: Joyant Pharmaceuticals, Inc.
    Inventors: Gunnar James Hanson, Qi Wei, Charles Caldwell, Ming Zhou, Lai Wang, Susan Harran
  • Indoline Anti-Cancer Agents
    Publication number: 20120264763
    Abstract: Indoline compounds having anti-mitotic activity, useful for the treatment of cancer and other proliferative disorders are provided.
    Type: Application
    Filed: July 25, 2011
    Publication date: October 18, 2012
    Inventors: Gunnar James Hanson, Qi Wei, Charles Caldwell, Ming Zhou, Lai Wang, Susan Harran
  • Diazonamide Analogs
    Publication number: 20120196907
    Abstract: Novel diazonamide analogs having anti-mitotic activity, useful for the treatment of cancer and other proliferative disorders are provided.
    Type: Application
    Filed: March 26, 2012
    Publication date: August 2, 2012
    Inventors: Gunnar James Hanson, Ming Zhou, Qui Wei, Charles Caldwell
  • Diazonamide analogs
    Patent number: 8153619
    Abstract: Novel diazonamide analogs having anti-mitotic activity, useful for the treatment of cancer and other proliferative disorders are provided.
    Type: Grant
    Filed: May 22, 2009
    Date of Patent: April 10, 2012
    Assignee: Joyant Pharmaceuticals, Inc.
    Inventors: Gunnar James Hanson, Ming Zhou, Qi Wei, Charles Caldwell
  • Dimeric Smac Mimetics
    Publication number: 20110195043
    Abstract: The invention provides small molecule mimics of the Smac peptide that are dimers or dimer-like compounds having two binding domains connected by a linker These compounds are useful to promote apoptosis. The invention includes pharmaceutical compositions comprising such compounds and methods to use them to treat conditions including cancer and autoimmune disorders.
    Type: Application
    Filed: October 28, 2010
    Publication date: August 11, 2011
    Inventors: Haizhou Sun, Xiaoming Xu, Ming Zhou, Susan Harran, Gunnar James Hanson, Lai Wang
  • Indoline anti-cancer agents
    Patent number: 7989482
    Abstract: Indoline compounds having anti-mitotic activity, useful for the treatment of cancer and other proliferative disorders are provided.
    Type: Grant
    Filed: April 29, 2009
    Date of Patent: August 2, 2011
    Assignee: Joyant Pharmaceuticals, Inc.
    Inventors: Gunnar James Hanson, Qi Wei, Charles Caldwell, Ming Zhou, Lai Wang, Susan Harran
  • Diazonamide analogs with improved solubility
    Patent number: 7960420
    Abstract: Diazonamide A analogs, and the salts, esters and conjugates thereof, having improved aqueous solubility are provided. Also provided are pharmaceutical compositions, and methods for preparing and using such compounds and compositions for the treatment of proliferative diseases.
    Type: Grant
    Filed: December 19, 2008
    Date of Patent: June 14, 2011
    Assignee: Joyant Pharmaceuticals, Inc
    Inventors: Gunnar James Hanson, Qi Wei, Ming Zhou
  • INDOLINE ANTI-CANCER AGENTS
    Publication number: 20100035946
    Abstract: Indoline compounds having anti-mitotic activity, useful for the treatment of cancer and other proliferative disorders are provided.
    Type: Application
    Filed: April 29, 2009
    Publication date: February 11, 2010
    Inventors: Gunnar James Hanson, Qi Wei, Charles Caldwell, Ming Zhou, Lai Wang, Susan Harran
  • DIAZONAMIDE ANALOGS
    Publication number: 20100022607
    Abstract: Novel diazonamide analogs having anti-mitotic activity, useful for the treatment of cancer and other proliferative disorders are provided.
    Type: Application
    Filed: May 22, 2009
    Publication date: January 28, 2010
    Inventors: Gunnar James Hanson, Ming Zhou, Qi Wei, Charles Caldwell
  • DIAZONAMIDE ANALOGS WITH IMPROVED SOLUBILITY
    Publication number: 20090163446
    Abstract: Diazonamide A analogs, and the salts, esters and conjugates thereof, having improved aqueous solubility are provided. Also provided are pharmaceutical compositions, and methods for preparing and using such compounds and compositions for the treatment of proliferative diseases.
    Type: Application
    Filed: December 19, 2008
    Publication date: June 25, 2009
    Inventors: Gunnar James HANSON, Qi Wei, Ming Zhou