Patents by Inventor Gunter Blobel

Gunter Blobel has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • ISOLATION OF LIVING CELLS AND PREPARATION OF CELL LINES BASED ON DETECTION AND QUANTIFICATION OF PRESELECTED CELLULAR RIBONUCLEIC ACID SEQUENCES
    Publication number: 20150143563
    Abstract: The invention is directed to reliable and efficient detection of mRNAs as well as other RNAs in living cells and its use to identify and, if desired, separate cells based on their desired characteristics. Such methods greatly simplify and reduce the time necessary to carry out previously-known procedures, and offers new approaches as well, such as selecting cells that generate a particular protein or antisense oligonucleotide, generating cell lines that express multiple proteins, generating cell lines with knock-out of one or more protein, and others.
    Type: Application
    Filed: January 16, 2015
    Publication date: May 21, 2015
    Inventors: Kambiz Shekdar, Gunter Blobel
  • ISOLATION OF LIVING CELLS AND PREPARATION OF CELL LINES BASED ON DETECTION AND QUANTIFICATION OF PRESELECTED CELLULAR RIBONUCLEIC ACID SEQUENCES
    Publication number: 20100212040
    Abstract: The invention is directed to reliable and efficient detection of mRNAs as well as other RNAs in living cells and its use to identify and, if desired, separate cells based on their desired characteristics. Such methods greatly simplify and reduce the time necessary to carry out previously-known procedures, and offers new approaches as well, such as selecting cells that generate a particular protein or antisense oligonucleotide, generating cell lines that express multiple proteins, generating cell lines with knock-out of one or more protein, and others.
    Type: Application
    Filed: April 30, 2010
    Publication date: August 19, 2010
    Applicant: CHROMOCELL CORPORATION
    Inventors: Kambiz Shekdar, Gunter Blobel
  • Isolation of living cells and preparation of cell lines based on detection and quantification of preselected cellular ribonucleic acid sequences
    Publication number: 20060147937
    Abstract: The invention is directed to reliable and efficient detection of mRNAs as well as other RNAs in living cells and its use to identify and, if desired, separate cells based on their desired characteristics. Such methods greatly simplify and reduce the time necessary to carry out previously-known procedures, and offers new approaches as well, such as selecting cells that generate a particular protein or antisense oligonucleotide, generating cell lines that express multiple proteins, generating cell lines with knock-out of one or more protein, and others.
    Type: Application
    Filed: September 2, 2003
    Publication date: July 6, 2006
    Inventors: Kambiz Shekdar, Gunter Blobel
  • Isolation of living cells and preparation of cell lines based on detection and quantification of preselected cellular ribonucleic acid sequences
    Patent number: 6692965
    Abstract: The invention is directed to reliable and efficient detection of mRNAs as well as other RNAs in living cells and its use to identify and, if desired, separate cells based on their desired characteristics. Such methods greatly simplify and reduce the time necessary to carry out previously-known procedures, and offers new approaches as well, such as selecting cells that generate a particular protein or antisense oligonucleotide, generating cell lines that express multiple proteins, generating cell lines with knock-out of one or more protein, and others.
    Type: Grant
    Filed: November 22, 2000
    Date of Patent: February 17, 2004
    Assignee: Chromocell Corporation
    Inventors: Kambiz Shekdar, Gunter Blobel
  • Monoclonal antibodies to nucleolar protein
    Patent number: 5811247
    Abstract: The invention relates to a hybridoma cell line which produces a monoclonal antibody which cross reacts with both yeast and human fibrillarin. Diagnostic kits are also described. These are useful in diagnosing diseases such as scleroderma.
    Type: Grant
    Filed: February 28, 1994
    Date of Patent: September 22, 1998
    Assignee: The Rockefeller University
    Inventors: John Aris, Gunter Blobel
  • Nucleic acid sequence which codes for and expresses human fibrillarin and uses thereof
    Patent number: 5310892
    Abstract: Substantially pure nucleic acid sequences coding for human fibrillarin have been identified and isolated. The isolated material is used to generate the protein in vitro, which is then used to identify autoimmune antibodies in patients suffering from scleroderma.
    Type: Grant
    Filed: December 10, 1990
    Date of Patent: May 10, 1994
    Assignee: The Rockefeller University
    Inventors: John Aris, Gunter Blobel